Kanker usus rayeuk, dituri sit seubagoe kanker kolorektal, disebabkan le pertumbuhan sel abnormal yang hana terkontrol di usus rayeuk atau rektum.
Penyebab pasti kanker usus rayeuk hana dituri, tapi padum-padum boh faktor jeut ji tingkatkan resiko peunyaket.
Nyoe termasuk:
1. Umu: Risiko kanker usus rayeuk meutamah deungen seumaken tuha, ngen sebagian rayek kasus terjadi bak ureung yang leubeh umu 50 thon.
2. Riwayat keluarga: Riwayat pribadi atawa keluarga kanker usus besar atau polip meningkatkan resiko peunyaket nyan.
3. Sindrom pewareh: Sindrom genetik pewareh tertentu, lage familial adenomatous polyposis (FAP) dan hereditary non-polyposis colorectal cancer (HNPCC), jeut ji tingkatkan resiko kanker usus besar.
4. Faktor gaya hidup: Diet yang le asoe mirah dan olahan, obesitas, merokok, dan konsumsi alkohol yang berlebihan jeut meningkatkan risiko kanker usus besar.
5. Penyakit radang usus: Penyakit radang usus jangka panyang, lage kolitis ulseratif dan penyakit Crohn, jeut ji tingkatkan resiko kanker usus.
6. Diabetes tipe 2: Ureueng nyang na diabetes tipe 2 leubeh jai resiko keunong kanker usus.
7. Terapi radiasi: Terapi radiasi untuk kanker laen di lambung jeut ji tingkatkan resiko kanker usus besar.
8. Ras: Afrika Amerika leubeh berisiko keunong kanker usus rayeuk daripada ras laen.
Penting untuk taingat bahwa na salah saboh atau leubeh dari faktor resiko nyo hana harus meuarti bahwa sidroe ureng akan mengembangkan kanker usus besar, dan padum droe ureng yang mengembangkan kanker usus besar mungken hana faktor resiko yang dituri.
Pemeriksaan rutin dan deteksi dini jeut membantu mencegah kanker usus besar atau mendeteksi jih bak tahap awai watee jeut diobati.
McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.
Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.
Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.
Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.
Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.
Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.
Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.
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['Kontak']
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What causes colon cancer?
Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.
The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.
These include:
1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.
2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.
3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.
4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.
5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.
6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.
7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.
8. Race: African Americans have a higher risk of developing colon cancer than other races.
It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.
Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.
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['Kamoe mulai deungen 35 juta publikasi biomedis PubMed/Medline. Meunan sit, halaman web RefinedWeb.']