Patofisiologi kanker payudara mengacu bak perubahan abnormal bak proses dan mekanisme fisiologis normal nyang terjadi bak perkembangan dan perkembangan kanker payudara.
Nyo melibatkan studi mekanisme biologis ngen molekuler yang mendasari yang meuakibat pertumbuhan ngen penyebaran sel kanker yang hana terkontrol dalam jaringan payudara.
Nyoe termasuk faktor genetik, epigenetik, dan lingkungan nyang berkontribusi bak inisiasi, promosi, dan perkembangan kanker payudara.
Beberapa perubahan patofisiologis utama bak kanker payudara termasuk:
1. Mutasi genetik: Mutasi bak gen tertentu, lage BRCA1 ngon BRCA2, jeut ji tingkatkan resiko ji kembangkan kanker payudara.
Mutasi nyo jeut diwariskan atau ji peroleh selama udep sidroe ureng
2. Ketidakseimbangan hormon: Hormon, terutama estrogen, jeut berperan dalam perkembangan dan pertumbuhan kanker payudara.
Saboh hana seimbang tingkat hormon atawa paparan estrogen yang leubeh jeut ji tingkatkan resiko kanker payudara.
3. Peradangan: Peradangan kronis bak jaringan payudara jeut berkontribusi bak perkembangan kanker payudara dengan mendorong pertumbuhan dan kelangsungan hidup sel kanker.
4. Lingkungan mikro tumor: Lingkungan di sekitar tumor, termasuk matriks ekstraseluler, sel kekebalan, dan pembuluh darah, jeut mempengaruhi pertumbuhan dan penyebaran kanker payudara.
5. Metastasis: Kanker payudara jeut menyebar ke bagian laen tuboh melalui sistem limfatik atau aliran darah, yang jeut keu pembentukan tumor sekunder di organ yang jioh.
Meuphom patofisiologi kanker payudara sangat peunteng untuk geu kembangkan pencegahan, deteksi dini, dan strategi perawatan nyang efektif.
Underwood SM: Breast cancer in African American women: nursing essentials. ABNF J. , 17 (1): 3-14.
Paliwal SR, Paliwal R, Agrawal GP, Vyas SP: Liposomal nanomedicine for breast cancer therapy. Nanomedicine (Lond). 2011, 6 (6): 1085-100.
Rauch GM, Adrada BE: Comparison of Breast MR Imaging with Molecular Breast Imaging in Breast Cancer Screening, Diagnosis, Staging, and Treatment Response Evaluation. Magn Reson Imaging Clin N Am. 2018, 26 (2): 273-280.
Wei H, Wang H, Ji Q, Sun J, Tao L, Zhou X: NRBP1 is downregulated in breast cancer and NRBP1 overexpression inhibits cancer cell proliferation through Wnt/β-catenin signaling pathway. Onco Targets Ther. 2015, 8 (): 3721-30.
Eden JA: Human breast cancer stem cells and sex hormones--a narrative review. Menopause. 2010, 17 (4): 801-10.
Schneider BP, Winer EP, Foulkes WD, Garber J, Perou CM, Richardson A, Sledge GW, Carey LA: Triple-negative breast cancer: risk factors to potential targets. Clin Cancer Res. 2008, 14 (24): 8010-8.
['Peuneugah: medis']
['Situs web nyoe hanya dipeutaba untuk tujuan pendidikan dan informasi dan hana merupakan nasehat medis atau layanan profesional.']
['Informasi nyang geubri hana jeut dipakek untuk mendiagnosis atau meuobati masalah kesehatan atau peunyaket, dan awak nyang mita nasehat medis pribadi harus berkonsultasi deungen dokter berlisensi.']
['Neuronal net nyang ji peuhase jawaban keu pertanyaan, khusus jih hana akurat wate ji peugah tentang konten numerik. miseu jih, jumlah ureung nyang ji diagnosa deungen peunyaket tertentu.']
['Sabe-sabe mita saran dari dokter atau penyedia kesehatan laen nyang berkualitas teuntang kondisi medis. Han tom neutilek nasihat medis profesional atawa neuterlambat mita jih kareuna na sesuatu nyang kaleuh neubaca bak situs web nyoe. Meunyo droeneuh pike droeneuh na darurat medis, hubungi 911 atawa neujak u ruang gawat darurat paleng toe langsong. Hana hubungan dokter-pasien nyang dipeuget le situs web nyoe atawa penggunaan jih. BioMedLib maupun karyawan jih, atawa kontributor situs web nyoe, hana dipeuget representasi, nyata atawa tersirat, teuntang informasi nyang geubri disinoe atawa penggunaan jih.']
['Peuneugah: hak cipta']
['Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the DMCA) geubi recourse keu ureung po hak cipta nyang yakin bahwa materi nyang deuh bak internet ji langgar hak awak nyan di miyup undang-undang hak cipta AS. ']
['Meunyo droeneuh yakin ngon get bahwa asoe atawa bahan nyang geupeutamöng lam hubôngan ngon website atawa layanan kamoe meulangga hak cipta droeneuh, droeneuh (atawa agen droeneuh) jeuet neukirém beuneuri keu kamoe ngön neulakèe mangat asoe atawa bahan nyan geusampôh, atawa geupeublok akses keujih.']
['Peumaklum haroh dikirim seucara tuleh deungen email (nging bagian "Kontak" untuk alamat email).']
['DMCA peurlee bahwa bewara droeneuh teuntang dugaan pelanggaran hak cipta teumasok informasi berikut: (1) deskripsi karya yang dilindungi hak cipta yang merupakan subjek klaim pelanggaran; (2) deskripsi konten yang diduga melanggar dan informasi yang cukup untuk memungkinkan kamoe untuk meutumeng konten; (3) informasi kontak untuk droeneuh, termasuk alamat, nomor telepon dan alamat email droeneuh; (4) pernyataan droeneuh bahwa droeneuh yakin bahwa konten yang diklaim hana diizinkan le pemilik hak cipta, atau agen jih, atau oleh operasi hukum apapun; ']
['(5) saboh pernyataan dari droeneuh, yang diteken deungen hukuman sumpah palsu, bahwa informasi lam pemberitahuan nyan akurat dan bahwa droeneuh na wewenang untuk menegakkan hak cipta yang diklaim dilanggar;']
['dan (6) tanda jaroe fisik atawa elektronik dari nyang po hak cipta atawa sidroe ureng nyang berwenang untuk bertindak atas nama nyang po hak cipta. ']
['Meunye hana neupeutamong mandum informasi di ateuh jeut keu akibat teulat meungurus keluhan droeneuh.']
['Kontak']
['Neukirem kheueh email keukamoe ateuh peue-peue nyang neutanyong atawa saran.']
What is pathophysiology of breast cancer?
Pathophysiology of breast cancer refers to the abnormal changes in the normal physiological processes and mechanisms that occur in the development and progression of breast cancer.
It involves the study of the underlying biological and molecular mechanisms that lead to the uncontrolled growth and spread of cancer cells in the breast tissue.
This includes the genetic, epigenetic, and environmental factors that contribute to the initiation, promotion, and progression of breast cancer.
Some of the key pathophysiological changes in breast cancer include:
1. Genetic mutations: Mutations in certain genes, such as BRCA1 and BRCA2, can increase the risk of developing breast cancer.
These mutations can be inherited or acquired during a person's lifetime.
2. Hormonal imbalances: Hormones, particularly estrogen, can play a role in the development and growth of breast cancer.
An imbalance in hormone levels or exposure to excess estrogen can increase the risk of breast cancer.
3. Inflammation: Chronic inflammation in the breast tissue can contribute to the development of breast cancer by promoting the growth and survival of cancer cells.
4. Tumor microenvironment: The environment surrounding the tumor, including the extracellular matrix, immune cells, and blood vessels, can influence the growth and spread of breast cancer.
5. Metastasis: Breast cancer can spread to other parts of the body through the lymphatic system or bloodstream, leading to the formation of secondary tumors in distant organs.
Understanding the pathophysiology of breast cancer is crucial for developing effective prevention, early detection, and treatment strategies.
Disclaimer: medical
This web site is provided for educational and informational purposes only and does not constitute providing medical advice or professional services.
The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.
Please note the neural net that generates answers to the questions, is specially inaccurate when it comes to numeric content. For example, the number of people diagnosed with a specific disease.
Always seek the advice of your doctor or other qualified health provider regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If you think you may have a medical emergency, call 911 or go to the nearest emergency room immediately. No physician-patient relationship is created by this web site or its use. Neither BioMedLib nor its employees, nor any contributor to this web site, makes any representations, express or implied, with respect to the information provided herein or to its use.
Disclaimer: copyright
The Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the “DMCA”) provides recourse for copyright owners who believe that material appearing on the Internet infringes their rights under U.S. copyright law. If you believe in good faith that any content or material made available in connection with our website or services infringes your copyright, you (or your agent) may send us a notice requesting that the content or material be removed, or access to it blocked. Notices must be sent in writing by email (see 'Contact' section for email address) . The DMCA requires that your notice of alleged copyright infringement include the following information: (1) description of the copyrighted work that is the subject of claimed infringement; (2) description of the alleged infringing content and information sufficient to permit us to locate the content; (3) contact information for you, including your address, telephone number and email address; (4) a statement by you that you have a good faith belief that the content in the manner complained of is not authorized by the copyright owner, or its agent, or by the operation of any law; (5) a statement by you, signed under penalty of perjury, that the information in the notification is accurate and that you have the authority to enforce the copyrights that are claimed to be infringed; and (6) a physical or electronic signature of the copyright owner or a person authorized to act on the copyright owner’s behalf. Failure to include all of the above information may result in the delay of the processing of your complaint.
['Teuntang']
['BioMedLib ji pakek komputer otomatis (algoritma pembelajaran meusen) untuk ji peuget pasangan pertanyaan ngen jawaban.']
['Kamoe mulai deungen 35 juta publikasi biomedis PubMed/Medline. Meunan sit, halaman web RefinedWeb.']
