Alzheimer se siekte word gediagnoseer deur 'n kombinasie van metodes, insluitend 'n deeglike mediese evaluering, kognitiewe en neuropsigologiese toetse, breinbeeldvorming en die proses om ander moontlike oorsake uit te skakel.
1. Mediese evaluering: 'n Dokter sal 'n fisiese ondersoek doen en 'n gedetailleerde mediese geskiedenis neem om ander moontlike oorsake van geheueverlies of kognitiewe agteruitgang uit te sluit, soos skildklierprobleme, vitamientekorte of breintumors.
2. Kognitiewe en neuropsigologiese toetse: Hierdie toetse beoordeel geheue, taal, probleemoplossing en ander kognitiewe funksies om die omvang van kognitiewe verswakking te bepaal en om te onderskei tussen normale ouderdomsverwante geheueverlies en demensie.
3. Breinbeelding: Magnetiese resonansiebeelding (MRI) of rekenaartomografie (CT) kan help om strukturele veranderinge in die brein te identifiseer wat op Alzheimer se siekte kan dui.
Positron-emissie-tomografie (PET) kan ook gebruik word om die vlakke van sekere proteïene wat met Alzheimer se siekte geassosieer word, te meet.
4. Bloedtoetse: Onlangse navorsing het getoon dat sekere bloedtoetse kan help om Alzheimer se siekte te diagnoseer deur die vlakke van spesifieke proteïene of biomarkers wat met die siekte geassosieer word, te meet.
5. Eliminasieproses: Aangesien daar nie 'n enkele definitiewe toets vir Alzheimer se siekte is nie, behels die diagnose dikwels dat ander moontlike oorsake van demensie-agtige simptome uitgesluit word.
Dit is belangrik om daarop te let dat 'n definitiewe diagnose van Alzheimer se siekte slegs na die dood gemaak kan word deur middel van 'n ondersoek van breinweefsel.
Huidige diagnostiese metodes kan egter 'n hoë vlak van sekerheid bied vir 'n kliniese diagnose terwyl die persoon nog lewe.
Vroeë diagnose is belangrik om met behandeling te begin en vir die toekoms te beplan.
Liu SS, Zhu SQ: [Correlation between Alzheimer disease and cataract]. Zhonghua Yan Ke Za Zhi. 2017, 53 (4): 314-316.
Gauthier S: Practical guidelines for the antemortem diagnosis of senile dementia of the Alzheimer type. Prog Neuropsychopharmacol Biol Psychiatry. 1985, 9 (5-6): 491-5.
Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.
[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.
Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.
Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.
Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.
Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.
Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.
Verwerping van verantwoordelikheid: mediese
Hierdie webwerf word slegs vir opvoedkundige en inligtingsdoeleindes verskaf en vorm nie die verskaffing van mediese advies of professionele dienste nie.
Die inligting wat verskaf word, moet nie gebruik word om 'n gesondheidsprobleem of siekte te diagnoseer of te behandel nie, en diegene wat persoonlike mediese advies soek, moet 'n gelisensieerde dokter raadpleeg.
Let asseblief daarop dat die neurale netwerk wat antwoorde op die vrae genereer, veral onakkuraat is wanneer dit kom by numeriese inhoud. Byvoorbeeld, die aantal mense wat met 'n spesifieke siekte gediagnoseer is.
Soek altyd die advies van jou dokter of ander gekwalifiseerde gesondheidsorgverskaffer oor 'n mediese toestand. Moet nooit professionele mediese advies ignoreer of vertraag om dit te soek as gevolg van iets wat jy op hierdie webwerf gelees het nie. As jy dink jy kan 'n mediese noodgeval hê, bel 911 of gaan onmiddellik na die naaste noodkamer. Geen dokter-pasiënt verhouding word geskep deur hierdie webwerf of die gebruik daarvan nie. Nie BioMedLib of sy werknemers, of enige bydraer tot hierdie webwerf, maak enige voorstellings, uitdruklik of implisiet, met betrekking tot die inligting wat hierin verskaf word of die gebruik daarvan.
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Kontak
Stuur asseblief vir ons 'n e-pos met enige vrae / voorstelle.
How is alzheimer diagnosed?
Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.
1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.
2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.
3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.
Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.
4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.
5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.
It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.
However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.
Early diagnosis is important for starting treatment and planning for the future.
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Please note the neural net that generates answers to the questions, is specially inaccurate when it comes to numeric content. For example, the number of people diagnosed with a specific disease.
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