Kansa ya mu mala, iyo beta no kuti colorectal cancer, ipangwa pa mulandu wa kuti insandesande ishishipema shilakula mu mala nelyo mu mulomo.
Icilenga kansa ya mu mala te kuti twishibe bwino bwino, lelo kwaliba ifintu ifingi ifingalenga umuntu ukulalwala sana.
Ifi fintu ni fi:
1. Imyaka: Ubulwele bwa kansa ya ku mukoshi bulakula ilyo tulekula, kabili ubulwele bwa kansa bwaba sana ku bantu abacilile imyaka 50.
2. Ulupwa: Umuntu nga alikwata kansa ya mu mala nelyo ama polyps mu lupwa, kuti alwala sana.
3. Ubulwele bwa ku fyalwa fye: Ubulwele bwa ku fyalwa fye pamo nga familial adenomatous polyposis (FAP) na hereditary non-polyposis colorectal cancer (HNPCC), kuti bwalenga umuntu ukukwata kansa ya ku mala.
4. Ifyo abantu bekala: Ukulalya sana inama ishashika, ukufina, ukupeepa, no kunwa sana ubwalwa kuti kwalenga umuntu ukulalwala kansa ya ku mukoshi.
5. Ubulwele bwa kulepuka kwa mala: Ubulwele bwa kulepuka kwa mala ubwatwalilila, pamo nga ulcerative colitis na Crohn's disease, kuti bwalenga umuntu ukukwata kansa ya ku mala.
6. Ubulwele bwa shuga ubwa Type 2: Abalwala ubulwele bwa shuga ubwa Type 2 balaba sana na kansa ya mu mala.
7. Ukundapa kwa kulepula: Ukundapa kwa kulepula kwa kansa imbi mu mala kuti kwalenga umuntu ukukwata kansa ya ku mukoshi.
8. Umushobo: Abena Afrika na bena Amerika balikwata ubusanso bwa kukwata kansa ya ku mukoshi ukucila aba mishobo imbi.
Cacindama ukwishiba ukuti ukukwata cimo pali ifi ifilenga ubulwele bwa kansa te kuti kulenge umuntu ukukwata kansa ya ku mukoshi, kabili abantu bamo abakwata kansa ya ku mukoshi nalimo tabakwata ifilenga ubulwele bwa kansa.
Ukuceeceeta lyonse no kwishiba bwangu ubulwele kuti kwacingilila kansa ya ku mukoshi nelyo ukumwishiba bwangu ilyo fye yacili iyapola.
McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.
Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.
Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.
Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.
Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.
Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.
Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.
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What causes colon cancer?
Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.
The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.
These include:
1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.
2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.
3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.
4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.
5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.
6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.
7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.
8. Race: African Americans have a higher risk of developing colon cancer than other races.
It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.
Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.
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