Ada babarapa pilihan pangobatan nang tasadia gasan kanker prostat, tagantung lawan stadium wan agresivitas kanker, wan jua kasihatan sabarataan pasien wan pilihan pribadi.
Beberapa perawatan umum mencakup:
1. Pengawasan aktif: Pendekatan ini malibatakan memantau kanker secara cermat lawan pemeriksaan wan tes rutin, daripada langsung memulai perawatan.
mungkin cocok gasan lakian lawan kanker prostat resiko rendah.
2. Operasi: Prostatektomi adalah prosedur bedah gasan manghapus kelenjar prostat.
kawa digawi lawan bedah tabuka atawa laparoskopi (manggunaakan sayatan halus wan alat khusus).
3. Terapi radiasi: Perawatan ini memakai radiasi energi tinggi gasan membunuh sel kanker.
kawa disampaiakan sacara eksternal (dari mesin di luar awak) atawa internal (melalui implan nang diandak parak tumor).
4. Terapi hormon: Perawatan ini mengurangi tingkat hormon lakian (androgen) di tubuh, nang kawa melambatakan atawa menghentikan pertumbuhan kanker prostat.
kawa dipakai saurangan atawa digabung lawan perawatan lain.
5. Kemoterapi: Perawatan ngini mamakai obat gasan mambunuh sel kanker.
kawa dipakai gasan kanker prostat nang sudah maju nang sudah manyabar ka bagian awak nang lain.
6. Imunoterapi: Perawatan ini membantu sistem kekebalan gasan melawan kanker.
kawa dipakai gasan kanker prostat nang sudah lanjut nang kada manjawab lawan perawatan lain.
7. Terapi nang ditarget: Terapi ini menarget gen atau protein tertentu nang membantu sel kanker tumbuh wan bertahan hidup.
kawa dipakai gasan kanker prostat nang sudah lanjut nang kada manjawab lawan perawatan lain.
8. Krioterapi: Perawatan ini memakai dingin nang ekstrim gasan membekuakan lawan mematikan sel kanker.
kawa dipakai gasan kanker prostat stadium awal atawa gasan kanker nang babulik imbah perawatan lain.
9. Ultrasound fokus intensitas tinggi (HIFU): Perawatan ini memakai gelombang suara frekuensi tinggi gasan memanasakan lawan menghancurkan sel kanker.
kawa dipakai gasan kanker prostat stadium awal atawa gasan kanker nang babulik imbah perawatan lain.
10. Menunggu dengan waspada: Pendekatan ini malibatakan memantau kanker secara cermat lawan pemeriksaan wan tes rutin, tapi kada mamulai perawatan kecuali gejala muncul atawa baubah.
mungkin cocok gasan lakian nang labih tuha lawan kanker prostat nang tumbuh lambat lawan kondisi kesehatan nang serius lainnya.
Penting gasan mendiskusikan seberataan pilihan perawatan lawan tim kesehatan gasan manantuakan tindakan nang paling baik gasan satiap kasus.
Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.
Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.
Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.
Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.
Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.
de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.
Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.
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How to treat prostate cancer?
There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.
Some common treatments include:
1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.
It may be suitable for men with low-risk prostate cancer.
2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.
It can be done through open surgery or laparoscopically (using small incisions and specialized tools).
3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.
It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).
4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.
It can be used alone or in combination with other treatments.
5. Chemotherapy: This treatment uses drugs to kill cancer cells.
It may be used for advanced prostate cancer that has spread to other parts of the body.
6. Immunotherapy: This treatment helps the immune system fight cancer.
It may be used for advanced prostate cancer that has not responded to other treatments.
7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.
It may be used for advanced prostate cancer that has not responded to other treatments.
8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.
It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.
9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.
It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.
10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.
It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.
It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.
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