The exact cause of prostate cancer is not known, but several factors have been identified that may increase the risk of developing the disease.
These include:
1. Age: The risk of prostate cancer increases with age, with most cases occurring in men over the age of 65.
2. Family history: Men with a family history of prostate cancer, particularly a father or brother with the disease, are at a higher risk.
3. Race: African American men have a higher risk of developing prostate cancer than men of other races.
4. Diet: A diet high in fat, particularly animal fat, may increase the risk of prostate cancer.
5. Obesity: Being overweight or obese may increase the risk of developing prostate cancer.
6. Hormones: High levels of testosterone and other male hormones may increase the risk of prostate cancer.
7. Inflammation: Chronic inflammation of the prostate, such as prostatitis, may increase the risk of prostate cancer.
8. Genetics: Certain inherited genetic mutations, such as those in the BRCA1 and BRCA2 genes, may increase the risk of prostate cancer.
It is important to note that having one or more of these risk factors does not mean that a man will definitely develop prostate cancer, and many men with prostate cancer have no known risk factors.
Additionally, research is ongoing to better understand the causes of prostate cancer and identify additional risk factors.
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Frydenberg M, Wijesinha S: Diagnosing prostate cancer - what GPs need to know. Aust Fam Physician. 2007, 36 (5): 345-7.
Shimodaira K, Nakashima J, Nakagami Y, Hirasawa Y, Hashimoto T, Satake N, Gondo T, Namiki K, Ohori M, Ohno Y: Prognostic Value of Platelet Counts in Patients with Metastatic Prostate Cancer Treated with Endocrine Therapy. Urol J. 2020, 17 (1): 42-49.
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