La malatie di Alzheimer e je diagnosticade midiant di une cumbinazion di metodis, che a includin une valutazion mediche aprofondide, provis cognitivis e neuropsicologjichis, imagjins dal cerviel, e il procès di eliminazion di altris pussibilis causis.
1. Esami medic: un miedi al fâs une visite mediche e al cjape une storie mediche detaiade par sclarî altris pussibilis causis di pierdite di memorie o declin cognitîf, come problemis de tiroide, mancjancis di vitamine o tumôrs al cerviel.
2. provis cognitivis e neuropsicologjichis: chestis provis a valutin la memorie, il lengaç, la risoluzion di problemis e altris funzions cognitivis par determinâ la entitât dal decjadiment cognitiv e par diferenziâ tra la normâl pierdite di memorie pe etât e la demence.
3. Immagjinis dal cerviel: lis imagjins a risonance magnetiche (MRI) o lis scansions tomografichis computerizadis (CT) a puedin judâ a identificâ cambiaments struturâi intal cerviel che a puedin indicâ la malatie di Alzheimer.
Lis scansions tomografichis a emission di positrons (PET) a puedin ancje jessi dopradis par misurâ i nivei di ciertis proteinis associadis cu la malatie di Alzheimer.
4. Esam dal sanc: Lis ricercjis resintis a àn mostrât che cierts esams dal sanc a puedin judâ a diagnosticâ la malatie dal Alzheimer midiant la misurazion dai nivei di specifichis proteinis o dai biomarkers associâts cu la malatie.
5 Procès di eliminazion: stant che nol è un test definitîf unic pe malatie di Alzheimer, la diagnosi spes e impliche escludi altris pussibilis causis di sintoms come la demence.
Al è impuartant savê che une diagnosi definitive de malatie di Alzheimer e pues jessi fate dome dopo la muart cuntun esam dal tiessût dal cerviel. ❚
Dut câs, i metodis di diagnostiche presints a puedin dâ un alt nivel di sigurece pe diagnosi cliniche cuant che la persone e je ancjemò in vite.
La diagnosi precoce e je impuartante par scomençâ la cure e progjetâ pal futûr.
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Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.
Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.
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How is alzheimer diagnosed?
Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.
1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.
2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.
3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.
Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.
4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.
5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.
It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.
However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.
Early diagnosis is important for starting treatment and planning for the future.
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