What is pathophysiology of Colon cancer?

['Nan jaawal ndu']

Ko woni patofisioloji nyau cancer ɓernde?

Pathophysiology cancer ɓaandu ɗon nufa dabareji be dabareji je ɗon yahda be yahde be yahde cancer ɓaandu.

Kansaru ɓernde, je ɓe ɗon anndira bo'o be kolorektal, lati irin kansaru je fuɗɗata ha nder ɓernde mala nder rectum, je lati nder ɓaandu je ɗon mari ɓaandu je ɗon mari sembe.

Footi fuɗɗa bana ɓesdol je ɓe ewni polyp, je footi wartira nyau cancer ha wakati.

Pathophysiology cancer ɓaandu ɗon larna sababuji jur, bana saanjolji tagdi, nyauji, be sababuji wakkere.

Tagle footi saanja nder DNA cellji ɓaandu, je ɗon hokka ɓesdugo be sendirol cellji je wala hakkilgo.

Tagle je mari irin tagdi ndu footi mara ndu, footi bo'o mara ndu, e footi memma tagidaadi feere-feere je ɗon mari nafuda ha maunugo, sendugo, e" mo " ittugo tagirɗi.

Wullol nder ɓaandu, je footi wona ngam nyau bana inflammatory bowel disease, footi ɓesda sababu cancer ɓaandu.

Wullol je ɗon tokkita footi waɗa yo'o kujeji kemikal wurtina je ɗon ɓesda ɓesdol cellji be sendol, footi waɗa nyau cancer.

Kujeji je ɗon larni, bana nyamdu, dabare ngeendam, be wondugo be kujeji kemikal feere footi bo'o mballa wangugo nyau cancer ɓernde.

Nyaamol je ɗon mari kujeji je ɗon mari iyam je ɗon mari iyam je ɗon mari kujeji je ɗon mari kujeji je ɗon mari kujeji, bana sappinol, ɗon yahida be ɓesdugo sababu cancer ɓaandu.

Kujeji feere bana buurna, foofugo, be shiya kugal ɓandu footi ɓesda sababu.

To nyau cancer ɓernde ɗon no fuɗɗa, footi yahra gal yahdeji feere-feere, diga yahde fuɗɗam je ɗon mari nyau ha nder ɓernde ha yahdeji je ɗon yahida be nyau man je ɗon sankiti ha wakkereji ɓaandu feere.

Tagirɗi cancer footi nasta nder ɓaandu be kujeji feere, footi bo'o sankita gal lymphatic system mala iyam ha wakkereji feere bana nder reedu mala fuffu.

Hurgol cancer ɓernde ɗon hawta be dabare hurgol, hurgol be dabareji chemotherapy be radiation, bana no yahde be wakkere cancer.

Lartol be hurgol be wakati woni ko nafata ngam yahde yeeso, ngam nyau cancer ɓernde ɗon footi hurga to a ɗon aandi ɗum be wakati fu.

Lartolji ha wakati fu, bana lartol ɓaandu, footi wallina heftugo cancer ɓaandu ha fuɗɗam, to footi hurgugo.

['Ɗaɓɓitol']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Vidal-Vanaclocha F: The liver prometastatic reaction of cancer patients: implications for microenvironment-dependent colon cancer gene regulation. Cancer Microenviron. 2011, 4 (2): 163-80.

Yagi T, Kubota E, Koyama H, Tanaka T, Kataoka H, Imaeda K, Joh T: Glucagon promotes colon cancer cell growth via regulating AMPK and MAPK pathways. Oncotarget. 2018, 9 (12): 10650-10664.

Chen JK, Yaffe MB: Atlas Drugged. Cell. 2019, 177 (4): 803-805.

Sharma SH, Thulasingam S, Nagarajan S: Terpenoids as anti-colon cancer agents - A comprehensive review on its mechanistic perspectives. Eur J Pharmacol. 2017, 795 (): 169-178.

Keshk WA, Zineldeen DH, Wasfy RE, El-Khadrawy OH: Fatty acid synthase/oxidized low-density lipoprotein as metabolic oncogenes linking obesity to colon cancer via NF-kappa B in Egyptians. Med Oncol. 2014, 31 (10): 192.

Dongfeng D, An C, Shujia P, Jikai Y, Tao Y, Rui D, Kai T, Yafeng C, Jianguo L, Xilin D: Explanation of colon cancer pathophysiology through analyzing the disrupted homeostasis of bile acids. Afr Health Sci. 2014, 14 (4): 925-8.

Tammali R, Ramana KV, Srivastava SK: Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Lett. 2007, 252 (2): 299-306.

['Wurtinol: jam ɓaandu']

['Web site ndu ɗon hokka ngam ekkitol be matinolji tan e wala bana hokkugo feeloji do jam ɓaandu mala kuɗe.']

["Matinolji je ɗon hokka footay huwire ngam lartol mala hurgol nyau mala nyauji, e ɓe'en je ɗon ɗaɓɓita feelo lekki sey ɓe laara do lekkitajo je mari jaawal."]

['Ladde ngam matinolji je ɗon wurtina jaawabuji do emmolji, lati bana je ɗon mari limgal je ɗon larni nyauɓe.']

['Footi a ɗaɓɓita jaahargal do lekkitajo ma mala goɗɗo dokkoowo jam ɓaandu je mari daama do nyau ma. Taa meema jaahargal do lekkitajo mala neeɓu ɗaɓɓugo ndu ngam ko a jaangi ha do wakkere web ndu. To a tammi a footi mara nyau jaawal, ewna 911 mala yah ha suudu jaawal je ɓadi ma be law. Wala alaka lekkitajo be nyauɗo je ɗon wangina gal wakkere web ndu mala huwugo ndu. BioMedLib mala huwooɓe ma, mala goɗɗo je ɗon walli ha wakkere web ndu, ɗon wolwa, ɗon holla mala ɗon nufa, do matinolji je ɗon hokka ha nder ndu mala huwugo ndu.']

['Wurtinol hakke: copyright']

["Digital Millennium Copyright Act je 1998, 17 U.S.C. § 512 (DMCA) ɗon hokka dabare ngam marɓe hakkeji je ɗon hoola yo'o kujeji je ɗon wangi ha do Internet ɗon luuta hakkeji maɓɓe do dooka hakkeji je Lesɗe America. "]

["To a ɗon nuɗɗini be nuɗɗinki boɗɗum yo'o kujeji mala kujeji je ɗon no wondi be web site mala kuɗe amin ɗon meema ceede je mari, an (mala wakili'en ma) footi nelda amin matinol je ɗon emma ngam ittugo kujeji mala kujeji, mala haɗugo heɓugo ndu. "]

['Matinolji sey nelda be ɗerewol gal emayel (laaru "Contact" ngam emayel).']

["DMCA yiɗi matinolji je ɗon bana ɗon larni matinolji je ɗon tokkitini: (1) tindol kugal je mari hakkeji je ɗon larni je ɗon tokkitini; (2) tindol kuje je ɗon larni je ɗon larni e matinolji je ɗon mari hakkeji je ɗon mari haaje ngam en heɓta kuje man; (3) matinolji ngam a wonda be ma, be lamar, lamba telefon be lamar email; (4) matinol je a holli a ɗon hoola be goonga yo'o kuje je ɗon no ɗon holla bana ɗon larni wala jaɓol marɗo hakkeji, mala wakiilijo maako, mala gal kugal dookaaji; "]

['(5) matinolji je on windi, je on windi ha les bone seedugo fewre, je matinolji ha nder matinolji man lati goonga e je on mari baawɗe ngam aynugo hakkeji je mbiyotto ɗon luuta;']

['e (6) jungo je ɗon mari hakkeji mala jungo je ɗon mari bawɗe huwugo ngam inde je mari hakkeji. ']

['Wattinugo matinolji je woni ha ton footi waɗa jaawal ngam jaɓɓugo do ngulli maɗa.']

['Wondugo']

['Lorte ha amin be emel to a mari ƴamol/dabare.']

What is pathophysiology of colon cancer?

The pathophysiology of colon cancer refers to the underlying mechanisms and processes that lead to the development and progression of colon cancer.

Colon cancer, also known as colorectal cancer, is a type of cancer that begins in the colon or rectum, which are parts of the large intestine.

It typically starts as a growth called a polyp, which can develop into cancer over time.

The pathophysiology of colon cancer involves several factors, including genetic mutations, inflammation, and environmental factors.

Genetic mutations can occur in the DNA of colon cells, leading to uncontrolled cell growth and division.

These mutations can be inherited or acquired, and they can affect various genes involved in cell growth, division, and repair.

Inflammation in the colon, which can be caused by conditions such as inflammatory bowel disease, can also increase the risk of colon cancer.

Chronic inflammation can lead to the release of chemicals that promote cell growth and division, potentially leading to the development of cancer.

Environmental factors, such as diet, lifestyle, and exposure to certain chemicals, can also contribute to the development of colon cancer.

A diet high in red and processed meats, for example, has been linked to an increased risk of colon cancer.

Other factors, such as obesity, smoking, and lack of physical activity, can also increase the risk.

Once colon cancer develops, it can progress through several stages, from early-stage cancer that is confined to the colon to more advanced stages where the cancer has spread to other parts of the body.

The cancer cells can invade nearby tissues and organs, and may also spread through the lymphatic system or bloodstream to distant sites, such as the liver or lungs.

Treatment for colon cancer typically involves a combination of surgery, chemotherapy, and radiation therapy, depending on the stage and location of the cancer.

Early detection and treatment are key to improving outcomes, as colon cancer is often curable when caught in its early stages.

Regular screening, such as colonoscopy, can help detect colon cancer at its earliest stages, when it is most treatable.

Disclaimer: medical

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Disclaimer: copyright

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