What causes Colon cancer?

['Èist ris an duilleag seo']

Dè tha ag adhbharachadh aillse a' cholaiste?

Tha aillse a' cholain, ris an canar cuideachd aillse colorectal, air adhbhrachadh le fàs neo-riaghlaichte de cheallan neo-àbhaisteach anns a' cholainn no an rectum.

Chan eil fios dè dìreach a dh' adhbhraicheas aillse a' cholaiste, ach tha grunn nithean ann a dh' fhaodas an cunnart a bhith a' fàs nas motha.

Tha iad sin a' gabhail a-steach:

1. Aois: Bidh an cunnart bho aillse a 'choin a' dol am meud le aois, leis a'mhòr-chuid de chùisean a' tachairt ann an daoine thairis air aois 50.

2. Eachdraidh teaghlaich: Bidh eachdraidh pearsanta no teaghlaich de aillse colon no polyps a'meudachadh cunnart an galair a leasachadh.

3. Syndromes oighreachail: Faodaidh cuid de syndromes ginteil oighreachail, leithid polyposis adenomatous teaghlaich (FAP) agus aillse colorectal neo-polyposis oighreachail (HNPCC), an cunnart bho aillse colon a mheudachadh.

4. Factaran dòigh-beatha: Faodaidh daithead àrd ann am feòil dhearg agus giullaichte, reamhar, smocadh, agus cus deoch làidir an cunnart a bhith a 'faighinn aillse colon.

5. Galar inflammatory bowel: Faodaidh galairean inflammatory bowel fad-ùine, leithid colitis ulcerative agus galar Crohn, an cunnart a bhith a 'faighinn aillse colon a mheudachadh.

6. Tinneas an t-siùcair seòrsa 2: Tha cunnart nas motha aig daoine le tinneas an t-siùcair seòrsa 2 aillse colon fhaighinn.

7. Leigheas rèididheachd: Faodaidh leigheas rèididheachd airson aillse eile sa bhroinn cunnart aillse a 'choin a mheudachadh.

8. Rèis: Tha cunnart nas àirde aig Ameireaganaich Afraganach aillse colon fhaighinn na rèisean eile.

Tha e cudromach a bhith mothachail nach eil a bhith a 'faighinn aon no barrachd de na factaran cunnairt sin a' ciallachadh gum bi neach a 'leasachadh aillse a' chollain, agus is dòcha nach eil factaran cunnairt aithnichte aig cuid de dhaoine a bhios a 'leasachadh aillse a' chollain.

Faodaidh sgrùdadh cunbhalach agus lorg tràth cuideachadh le bhith a 'cur casg air aillse colon no ga lorg aig ìre thràth nuair a tha e nas gabhaltach a làimhseachadh.

['Tagraidhean']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.

Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.

Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.

Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.

Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.

Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.

Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.

['Àicheadh: meidigeach']

["Tha an làrach-lìn seo air a thoirt seachad airson adhbharan foghlaim agus fiosrachaidh a-mhàin agus chan eil e a' toirt seachad comhairle mheidigeach no seirbheisean proifeiseanta."]

["Cha bu chòir am fiosrachadh a chaidh a thoirt seachad a chleachdadh airson duilgheadas slàinte no galar a dhearbhadh no a làimhseachadh, agus bu chòir dhaibhsan a tha a'sireadh comhairle meidigeach pearsanta co-chomhairle a chumail ri lighiche-sprèidh."]

["Thoiribh fa-near gu bheil an lìon neural a tha a' cruthachadh fhreagairtean do na ceistean, gu sònraichte neo-chruinneasach nuair a thig e gu susbaint àireamhach. Mar eisimpleir, an àireamh de dhaoine a chaidh a dhearbhadh le galar sònraichte."]

["Faigh comhairle an dotair agad no solaraiche slàinte eile a tha airidh air comhairle a thaobh tinneas meidigeach. Na dì-meas comhairle meidigeach proifeiseanta no dàil ann a bhith ga shireadh air sgàth rudeigin a leugh thu air an làrach-lìn seo. Ma tha thu a'smaoineachadh gum faodadh èiginn meidigeach a bhith agad, cuir fòn gu 911 no rachaibh chun t-seòmar èiginn as fhaisge sa bhad. Chan eil dàimh dotair-euslainteach air a chruthachadh leis an làrach-lìn seo no a chleachdadh. Chan eil BioMedLib no a luchd-obrach, no neach sam bith a tha a' cur ris an làrach-lìn seo, a 'dèanamh riochdachaidhean sam bith, fosgailte no a' toirt a-steach, a thaobh an fhiosrachaidh a tha air a thoirt seachad an seo no a chleachdadh."]

['Àicheadh: còraichean']

["Tha Achd Dlighe-sgrìobhaidh na Mìle Bliadhna Didseatach 1998, 17 U.S.C. § 512 (an DMCA) a' toirt ath-chuinge do shealbhadairean dlighe-sgrìobhaidh a tha den bheachd gu bheil stuth a tha a' nochdadh air an eadar-lìon a' briseadh an còraichean fo lagh dlighe-sgrìobhaidh na SA. "]

["Ma tha thu a' creidsinn ann an deagh chreideamh gu bheil susbaint no stuth sam bith a tha ri fhaotainn a thaobh ar làrach-lìn no ar seirbheisean a' briseadh d' dlighe-sgrìobhaidh, faodaidh tu fhèin (no an riochdaire agad) fios a chur thugainn ag iarraidh gun tèid an susbaint no an stuth a thoirt air falbh, no gun tèid cothrom a chur air. "]

["Feumar sanasan a chur ann an sgrìobhadh tro phost-d (faic an roinn 'Contact' airson seòladh puist-d). "]

["Tha an DMCA ag iarraidh gum bi am fiosrachadh a leanas anns an fhios agad mu bhriseadh còraichean-sgrìobhaidh a thathar ag ràdh: (1) tuairisgeul air an obair fo chòraichean-sgrìobhaidh a tha fo chasaid briseadh; (2) tuairisgeul air an t-susbaint a thathar ag ràdh a tha a 'briseadh agus fiosrachadh gu leòr gus leigeil leinn an t-susbaint a lorg; (3) fiosrachadh conaltraidh dhut, a' toirt a-steach do sheòladh, àireamh fòn agus seòladh puist-d; (4) aithris bhuat gu bheil creideas math agad nach eil an t-susbaint san dòigh a tha gearan air a cheadachadh le sealbhadair a 'chòraichean-sgrìobhaidh, no an neach-ionaid aige, no le gnìomh lagha sam bith; "]

['(5) Dearbhadh agaibh, air a shoidhnigeadh fo pheanas mionnachaidh, gu bheil am fiosrachadh san fhiosrachadh ceart agus gu bheil ùghdarras agaibh na còraichean-sgrìobhaidh a thathar ag ràdh a chaidh a bhriseadh a chur an gnìomh; ']

['agus (6) ainm-sgrìobhte corporra no eileagtronaigeach an t-sealbhadair dlighe-sgrìobhaidh no neach a tha ùghdarraichte a bhith ag obair às leth an t-sealbhadair dlighe-sgrìobhaidh. ']

["Ma dh'fhailicheas tu air a' ghearan agad a dheasachadh, faodaidh e dàil a chur air mura cuir thu a-steach am fiosrachadh gu lèir gu h-àrd."]

['Cuir fios thugainn']

['Cuir post-d thugainn le ceist / moladh sam bith.']

What causes colon cancer?

Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.

The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.

These include:

1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.

2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.

3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.

4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.

5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.

6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.

7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.

8. Race: African Americans have a higher risk of developing colon cancer than other races.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.

Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.

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