Dè a th 'ann am pathophysiology de thinneas an t-siùcair?
Tha pathophysiology de thinneas an t-siùcair a' toirt iomradh air sgrùdadh nan pròiseasan fiseòlasach eas-òrdugh a tha a' leantainn gu leasachadh tinneas an t-siùcair.
Tha tinneas an t-siùcair mellitus na bhuidheann de ghalaran metabolach air a bheil ìrean siùcair fala àrd (glucose) mar thoradh air lochdan ann an secretion insulin, gnìomh insulin, no an dà chuid.
Tha pathophysiology tinneas an t-siùcair a 'toirt a-steach eadar-obrachadh iom-fhillte de fhactaran ginteil, àrainneachdail, agus dòigh-beatha a tha a' cur ri leasachadh a 'ghalair.
Ann an tinneas an t-siùcair seòrsa 1, tha am pathophysiology a 'toirt a-steach sgrios fèin-dìonach de na ceallan beta a tha a' dèanamh insulin anns a 'phancreas, a tha a' leantainn gu easbhaidh ann an cinneasachadh insulin.
Tha seo a 'leantainn gu neo-chomas ìrean glùcois fala a riaghladh, a' leantainn gu hyperglycemia (siùcar fuil àrd).
Ann an tinneas an t-siùcair seòrsa 2, tha am pathophysiology nas iom-fhillte agus tha e a 'toirt a-steach an dà chuid strì an aghaidh insulin agus secretion insulin lagaichte.
Bidh strì an aghaidh insulin a' tachairt nuair nach bi ceallan a' chuirp a' freagairt gu ceart ri insulin, a' leantainn gu neo-chomas glucose a chleachdadh gu h-èifeachdach airson lùth.
Bidh seo ag adhbhrachadh gum bi am pancreas a 'dèanamh barrachd insulin gus feuchainn ris an aghaidh a thoirt air falbh, ach thar ùine, is dòcha nach bi am pancreas comasach air cumail suas ris an iarrtas, a' leantainn gu lùghdachadh ann an cinneasachadh insulin.
Tha tinneas an t-siùcair gestational, a tha a' tachairt rè torrachas, air adhbhrachadh le atharrachaidhean hormonail a tha a' leantainn gu strì an aghaidh insulin.
Bidh am placenta a 'dèanamh hormonaichean a dh' fhaodas casg a chuir air gnìomh insulin, a 'leantainn gu àrdachadh ann an ìrean glùcois fala.
Tha pathophysiology tinneas an t-siùcair cuideachd a' toirt a-steach leasachadh dhuilgheadasan, leithid milleadh air soithichean fala, nearbhan, agus organan, a dh'fhaodas leantainn gu duilgheadasan slàinte dona mar tinneas cridhe, stròc, tinneas dubhaig, agus call lèirsinn.
Tha tuigse air pathophysiology tinneas an t-siùcair deatamach airson a bhith a 'leasachadh leigheasan èifeachdach agus ro-innleachdan casg airson a' ghalair leantainneach seo.
Biochemistry and pathophysiology of diabetes. Proceedings of conference on pathophysiology and treatment of diabetes mellitus. 1990. Mol Cell Biochem. 1992, 109 (2): 97-204.
Surampudi PN, John-Kalarickal J, Fonseca VA: Emerging concepts in the pathophysiology of type 2 diabetes mellitus. Mt Sinai J Med. 2009, 76 (3): 216-26.
Johnson D: Selected pathophysiology of diabetes. Semin Perioper Nurs. 1998, 7 (3): 164-78.
Hirsch IB: The changing faces of diabetes. Prim Care. 2003, 30 (3): 499-510.
Guthrie RA, Guthrie DW: Pathophysiology of diabetes mellitus. Crit Care Nurs Q. , 27 (2): 113-25.
Felig P: Pathophysiology of diabetes mellitus. Med Clin North Am. 1971, 55 (4): 821-34.
['Àicheadh: meidigeach']
["Tha an làrach-lìn seo air a thoirt seachad airson adhbharan foghlaim agus fiosrachaidh a-mhàin agus chan eil e a' toirt seachad comhairle mheidigeach no seirbheisean proifeiseanta."]
["Cha bu chòir am fiosrachadh a chaidh a thoirt seachad a chleachdadh airson duilgheadas slàinte no galar a dhearbhadh no a làimhseachadh, agus bu chòir dhaibhsan a tha a'sireadh comhairle meidigeach pearsanta co-chomhairle a chumail ri lighiche-sprèidh."]
["Thoiribh fa-near gu bheil an lìon neural a tha a' cruthachadh fhreagairtean do na ceistean, gu sònraichte neo-chruinneasach nuair a thig e gu susbaint àireamhach. Mar eisimpleir, an àireamh de dhaoine a chaidh a dhearbhadh le galar sònraichte."]
["Faigh comhairle an dotair agad no solaraiche slàinte eile a tha airidh air comhairle a thaobh tinneas meidigeach. Na dì-meas comhairle meidigeach proifeiseanta no dàil ann a bhith ga shireadh air sgàth rudeigin a leugh thu air an làrach-lìn seo. Ma tha thu a'smaoineachadh gum faodadh èiginn meidigeach a bhith agad, cuir fòn gu 911 no rachaibh chun t-seòmar èiginn as fhaisge sa bhad. Chan eil dàimh dotair-euslainteach air a chruthachadh leis an làrach-lìn seo no a chleachdadh. Chan eil BioMedLib no a luchd-obrach, no neach sam bith a tha a' cur ris an làrach-lìn seo, a 'dèanamh riochdachaidhean sam bith, fosgailte no a' toirt a-steach, a thaobh an fhiosrachaidh a tha air a thoirt seachad an seo no a chleachdadh."]
['Àicheadh: còraichean']
["Tha Achd Dlighe-sgrìobhaidh na Mìle Bliadhna Didseatach 1998, 17 U.S.C. § 512 (an DMCA) a' toirt ath-chuinge do shealbhadairean dlighe-sgrìobhaidh a tha den bheachd gu bheil stuth a tha a' nochdadh air an eadar-lìon a' briseadh an còraichean fo lagh dlighe-sgrìobhaidh na SA. "]
["Ma tha thu a' creidsinn ann an deagh chreideamh gu bheil susbaint no stuth sam bith a tha ri fhaotainn a thaobh ar làrach-lìn no ar seirbheisean a' briseadh d' dlighe-sgrìobhaidh, faodaidh tu fhèin (no an riochdaire agad) fios a chur thugainn ag iarraidh gun tèid an susbaint no an stuth a thoirt air falbh, no gun tèid cothrom a chur air. "]
["Feumar sanasan a chur ann an sgrìobhadh tro phost-d (faic an roinn 'Contact' airson seòladh puist-d). "]
["Tha an DMCA ag iarraidh gum bi am fiosrachadh a leanas anns an fhios agad mu bhriseadh còraichean-sgrìobhaidh a thathar ag ràdh: (1) tuairisgeul air an obair fo chòraichean-sgrìobhaidh a tha fo chasaid briseadh; (2) tuairisgeul air an t-susbaint a thathar ag ràdh a tha a 'briseadh agus fiosrachadh gu leòr gus leigeil leinn an t-susbaint a lorg; (3) fiosrachadh conaltraidh dhut, a' toirt a-steach do sheòladh, àireamh fòn agus seòladh puist-d; (4) aithris bhuat gu bheil creideas math agad nach eil an t-susbaint san dòigh a tha gearan air a cheadachadh le sealbhadair a 'chòraichean-sgrìobhaidh, no an neach-ionaid aige, no le gnìomh lagha sam bith; "]
['(5) Dearbhadh agaibh, air a shoidhnigeadh fo pheanas mionnachaidh, gu bheil am fiosrachadh san fhiosrachadh ceart agus gu bheil ùghdarras agaibh na còraichean-sgrìobhaidh a thathar ag ràdh a chaidh a bhriseadh a chur an gnìomh; ']
['agus (6) ainm-sgrìobhte corporra no eileagtronaigeach an t-sealbhadair dlighe-sgrìobhaidh no neach a tha ùghdarraichte a bhith ag obair às leth an t-sealbhadair dlighe-sgrìobhaidh. ']
["Ma dh'fhailicheas tu air a' ghearan agad a dheasachadh, faodaidh e dàil a chur air mura cuir thu a-steach am fiosrachadh gu lèir gu h-àrd."]
['Cuir fios thugainn']
['Cuir post-d thugainn le ceist / moladh sam bith.']
What is pathophysiology of diabetes?
Pathophysiology of diabetes refers to the study of the disordered physiological processes that lead to the development of diabetes mellitus.
Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels that result from defects in insulin secretion, insulin action, or both.
The pathophysiology of diabetes involves the complex interplay of genetic, environmental, and lifestyle factors that contribute to the development of the disease.
In type 1 diabetes, the pathophysiology involves an autoimmune destruction of the insulin-producing beta cells in the pancreas, leading to a deficiency in insulin production.
This results in an inability to regulate blood glucose levels, leading to hyperglycemia (high blood sugar).
In type 2 diabetes, the pathophysiology is more complex and involves both insulin resistance and impaired insulin secretion.
Insulin resistance occurs when the body's cells do not respond properly to insulin, leading to an inability to effectively use glucose for energy.
This causes the pancreas to produce more insulin to try to overcome the resistance, but over time, the pancreas may not be able to keep up with the demand, leading to a decrease in insulin production.
Gestational diabetes, which occurs during pregnancy, is caused by hormonal changes that lead to insulin resistance.
The placenta produces hormones that can block the action of insulin, leading to an increase in blood glucose levels.
The pathophysiology of diabetes also involves the development of complications, such as damage to blood vessels, nerves, and organs, which can lead to serious health problems like heart disease, stroke, kidney disease, and vision loss.
Understanding the pathophysiology of diabetes is crucial for developing effective treatments and prevention strategies for this chronic disease.
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