Tagraíonn pathophysiology ailse colon do na meicníochtaí agus na próisis bunúsacha a fhágann go bhforbrófar agus go dtéann ailse colon chun cinn.
Is cineál ailse é ailse colon, ar a dtugtar ailse colorectal freisin, a thosaíonn sa colon nó sa rectum, atá mar chuid den intestine mór.
De ghnáth tosaíonn sé mar fhás ar a dtugtar polyp, a d'fhéadfadh forbairt ina ailse le himeacht ama.
Baineann pathophysiology ailse colon le roinnt fachtóirí, lena n-áirítear mutations géiniteacha, athlasadh, agus fachtóirí comhshaoil.
D'fhéadfadh mutations géiniteacha tarlú i DNA cealla colon, rud a fhágann go bhfásann agus go roinneann cealla gan smacht.
Is féidir na mutations seo a oidhreacht nó a fháil, agus is féidir leo tionchar a imirt ar géiní éagsúla a bhfuil baint acu le fás, roinn, agus deisiú cealla.
Is féidir le athlasadh sa colon, a d'fhéadfadh a bheith mar thoradh ar choinníollacha cosúil le galar athlasadh intestinal, an baol ailse colon a mhéadú freisin.
D'fhéadfadh athlasadh ainsealach a bheith ina chúis le ceimiceáin a scaoileadh a chuireann fás agus roinn cealla chun cinn, rud a d'fhéadfadh forbairt ailse a dhéanamh.
Is féidir le fachtóirí comhshaoil, mar shampla aiste bia, stíl mhaireachtála, agus nochtadh do cheimiceáin áirithe, cur le forbairt ailse colon freisin.
Tá baint ag aiste bia a bhfuil go leor feola dearg agus próiseáilte ann, mar shampla, le riosca méadaithe ailse colon.
Is féidir le fachtóirí eile, mar shampla otracht, caitheamh tobac, agus easpa gníomhaíochta choirp, an riosca a mhéadú freisin.
Nuair a d'fhorbair ailse colon, d'fhéadfadh sé dul chun cinn trí roinnt céimeanna, ó ailse céim luath atá teoranta don colon go céimeanna níos airde ina bhfuil an ailse scaipthe go codanna eile den chorp.
Is féidir leis na cealla ailse ionsaí a dhéanamh ar fíocháin agus ar orgáin in aice láimhe, agus d'fhéadfadh siad scaipeadh tríd an gcóras lymphatic nó an sruth fola go suíomhanna i bhfad i gcéin, mar shampla an ae nó na scamhóga.
Is gnách go mbaineann cóireáil le haghaidh ailse colon le meascán de máinliacht, ceimiteiripe, agus teiripe radaíochta, ag brath ar chéim agus ar shuíomh an ailse.
Tá braite agus cóireáil luath ríthábhachtach chun torthaí a fheabhsú, ós rud é go bhfuil ailse colon inléite go minic nuair a ghabhtar é ina chéimeanna luatha.
Is féidir le scagadh rialta, mar shampla colonoscopy, cabhrú le ailse colon a bhrath ina chéimeanna is luaithe, nuair is féidir é a chóireáil is fearr.
Vidal-Vanaclocha F: The liver prometastatic reaction of cancer patients: implications for microenvironment-dependent colon cancer gene regulation. Cancer Microenviron. 2011, 4 (2): 163-80.
Yagi T, Kubota E, Koyama H, Tanaka T, Kataoka H, Imaeda K, Joh T: Glucagon promotes colon cancer cell growth via regulating AMPK and MAPK pathways. Oncotarget. 2018, 9 (12): 10650-10664.
Sharma SH, Thulasingam S, Nagarajan S: Terpenoids as anti-colon cancer agents - A comprehensive review on its mechanistic perspectives. Eur J Pharmacol. 2017, 795 (): 169-178.
Keshk WA, Zineldeen DH, Wasfy RE, El-Khadrawy OH: Fatty acid synthase/oxidized low-density lipoprotein as metabolic oncogenes linking obesity to colon cancer via NF-kappa B in Egyptians. Med Oncol. 2014, 31 (10): 192.
Dongfeng D, An C, Shujia P, Jikai Y, Tao Y, Rui D, Kai T, Yafeng C, Jianguo L, Xilin D: Explanation of colon cancer pathophysiology through analyzing the disrupted homeostasis of bile acids. Afr Health Sci. 2014, 14 (4): 925-8.
Tammali R, Ramana KV, Srivastava SK: Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Lett. 2007, 252 (2): 299-306.
Diúltú freagrachta: leighis
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Níor cheart an t-eolas a chuirtear ar fáil a úsáid chun fadhb sláinte nó galar a dhiagnóisiú nó a chóireáil, agus ba cheart dóibh siúd atá ag lorg comhairle leighis phearsanta dul i gcomhairle le dochtúir ceadúnaithe.
Tabhair faoi deara le do thoil go bhfuil an líonra néarónach a ghineann freagraí ar na ceisteanna, míchruinn go háirithe nuair a bhaineann sé le hábhar uimhriúil. Mar shampla, líon na ndaoine a ndearnadh diagnóis orthu le galar ar leith.
Déan comhairle do dhochtúir nó do sholáthraí sláinte cáilithe eile i gcónaí maidir le riocht leighis. Ná déan neamhaird ar chomhairle leighis ghairmiúil ná déileáil leis mar gheall ar rud éigin a léigh tú ar an suíomh Gréasáin seo. Má cheapann tú go bhféadfadh éigeandáil leighis a bheith agat, glaoigh ar 911 nó téigh go dtí an seomra éigeandála is gaire láithreach. Ní chruthaíonn an suíomh Gréasáin seo ná a úsáid aon chaidreamh dochtúir-othar. Ní dhéanann BioMedLib ná a chuid fostaithe, ná aon ranníocóir leis an suíomh Gréasáin seo aon ionadaíochtaí, sainráite nó intuigthe, maidir leis an bhfaisnéis a sholáthraítear anseo ná a úsáid.
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Cumarsáid
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What is pathophysiology of colon cancer?
The pathophysiology of colon cancer refers to the underlying mechanisms and processes that lead to the development and progression of colon cancer.
Colon cancer, also known as colorectal cancer, is a type of cancer that begins in the colon or rectum, which are parts of the large intestine.
It typically starts as a growth called a polyp, which can develop into cancer over time.
The pathophysiology of colon cancer involves several factors, including genetic mutations, inflammation, and environmental factors.
Genetic mutations can occur in the DNA of colon cells, leading to uncontrolled cell growth and division.
These mutations can be inherited or acquired, and they can affect various genes involved in cell growth, division, and repair.
Inflammation in the colon, which can be caused by conditions such as inflammatory bowel disease, can also increase the risk of colon cancer.
Chronic inflammation can lead to the release of chemicals that promote cell growth and division, potentially leading to the development of cancer.
Environmental factors, such as diet, lifestyle, and exposure to certain chemicals, can also contribute to the development of colon cancer.
A diet high in red and processed meats, for example, has been linked to an increased risk of colon cancer.
Other factors, such as obesity, smoking, and lack of physical activity, can also increase the risk.
Once colon cancer develops, it can progress through several stages, from early-stage cancer that is confined to the colon to more advanced stages where the cancer has spread to other parts of the body.
The cancer cells can invade nearby tissues and organs, and may also spread through the lymphatic system or bloodstream to distant sites, such as the liver or lungs.
Treatment for colon cancer typically involves a combination of surgery, chemotherapy, and radiation therapy, depending on the stage and location of the cancer.
Early detection and treatment are key to improving outcomes, as colon cancer is often curable when caught in its early stages.
Regular screening, such as colonoscopy, can help detect colon cancer at its earliest stages, when it is most treatable.
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