What causes Colon cancer?

Apa sing nyebabké kanker usus?

Kanker kolon, uga dikenal minangka kanker kolorektal, disebabake dening tuwuhing sel abnormal sing ora dikendhaleni ing kolon utawa rektum.

Penyebab kanker usus besar sing tepat ora dingerteni, nanging sawetara faktor bisa nambah risiko ngembangake penyakit kasebut.

Iki kalebu:

1. Umur: Risiko kanker usus besar mundhak kanthi umur, kanthi umume kasus kedadeyan ing wong sing umure luwih saka 50 taun.

2. Riwayat kulawarga: Riwayat pribadi utawa kulawarga kanker usus besar utawa polip nambah risiko ngembangake penyakit kasebut.

3. Sindrom sing diwarisake: Sindrom genetik sing diwarisake, kayata poliposis adenomatous familial (FAP) lan kanker kolorektal non-poliposis hereditary (HNPCC), bisa nambah risiko kanker usus besar.

4. Faktor gaya urip: Diet sing akeh daging abang lan olahan, obesitas, ngrokok, lan konsumsi alkohol sing berlebihan bisa nambah risiko kanker usus besar.

5. Penyakit radang usus: Penyakit radang usus jangka panjang, kayata kolitis ulseratif lan penyakit Crohn, bisa nambah risiko kanker usus besar.

6. Diabetes tipe 2: Wong sing ngalami diabetes tipe 2 duwe risiko luwih dhuwur kanggo nandhang kanker usus besar.

7. Terapi radiasi: Terapi radiasi kanggo kanker liyane ing weteng bisa nambah risiko kanker usus besar.

8. Ras: Afrika-Amerika duwe risiko luwih dhuwur kanggo ngalami kanker usus besar tinimbang ras liyane.

Penting kanggo dicathet yen duwe siji utawa luwih saka faktor risiko kasebut ora ateges manawa wong bakal ngalami kanker usus, lan sawetara wong sing ngalami kanker usus bisa uga ora duwe faktor risiko sing dingerteni.

Skrining rutin lan deteksi awal bisa mbantu nyegah kanker usus besar utawa ndeteksi ing tahap awal nalika bisa diobati.

Referensi-referensi

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.

Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.

Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.

Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.

Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.

Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.

Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.

Penafian: medis

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Informasi sing diwenehake ora kudu digunakake kanggo diagnosa utawa ngobati masalah utawa penyakit kesehatan, lan wong-wong sing golek saran medis pribadi kudu takon karo dokter sing duwe lisensi.

Mangga dicathet jaringan saraf sing ngasilake wangsulan kanggo pitakonan, utamané ora akurat nalika nerangake konten numerik. Contone, jumlah wong sing didiagnosis karo penyakit tartamtu.

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Yen sampeyan percaya kanthi tulus manawa konten utawa materi sing kasedhiya gegayutan karo situs web utawa layanan kita nglanggar hak cipta sampeyan, sampeyan (utawa agen sampeyan) bisa ngirim kabar kanggo njaluk supaya konten utawa materi kasebut dicopot, utawa akses diblokir.

Kabar kudu dikirim kanthi nulis liwat email (deleng bagean "Kontak" kanggo alamat email).

DMCA mbutuhake kabar sampeyan babagan pelanggaran hak cipta sing diduga kalebu informasi ing ngisor iki: (1) deskripsi karya hak cipta sing dadi subyek pelanggaran sing diduga; (2) deskripsi konten sing diduga nglanggar lan informasi sing cukup kanggo ngidini kita nemokake konten kasebut; (3) informasi kontak kanggo sampeyan, kalebu alamat, nomer telpon lan alamat email; (4) pernyataan dening sampeyan yen sampeyan duwe kapercayan sing apik yen konten kanthi cara sing dikritik ora diidini dening pemilik hak cipta, utawa agen, utawa dening operasi hukum apa wae;

(5) pratelan dening sampeyan, ditandatangani kanthi paukuman sumpah palsu, manawa informasi ing pemberitahuan kasebut akurat lan sampeyan duwe wewenang kanggo ngetrapake hak cipta sing diklaim dilanggar;

lan (6) tandha tangan fisik utawa elektronik saka pemilik hak cipta utawa wong sing sah tumindak atas jenenge pemilik hak cipta.

Ora kalebu kabeh informasi ing ndhuwur bisa nyebabake wektu tundha kanggo ngolah keluhan sampeyan.

Kontak karo

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What causes colon cancer?

Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.

The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.

These include:

1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.

2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.

3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.

4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.

5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.

6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.

7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.

8. Race: African Americans have a higher risk of developing colon cancer than other races.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.

Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.

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