What are the risk factors for Colon cancer?

['Ĩthukĩĩsye ũvoo ũũ']

Nĩ maũndũ meva matonya kũtuma mũndũ akwatwa nĩ kanza ya kĩthũi?

1. Ũkũũ: Mũndũ akũa ethĩawa na ũisyo mwingangĩ wa kũkwata kanza ya kĩthũi nũndũ andũ aingĩ makwataa kanza ĩsu me na myaka 50 na kĩndũ.

2. Ethĩwa tene waĩ na tũlungu tũnini twa mavĩndĩ kana kanza ya mavĩndĩ: Ethĩwa ve ĩvinda waĩ na tũlungu tũnini twa mavĩndĩ kana kanza ya mavĩndĩ, nĩ laisi ũkakwata ĩngĩ.

3. Andũ amwe ma mũsyĩ nĩmatonya kwĩthĩwa maĩ na kanza ya kĩthũi: Ethĩwa ve andũ ma mũsyĩ maĩ na kanza ya kĩthũi, nĩ laisi ũkakwatwa nĩyo.

4. Ũwau wa kũvĩvw'a kwa mavĩndĩ: Andũ ala makwatawa nĩ mowau ta ũwau wa kũvĩvw'a kwa mavĩndĩ (ulcerative colitis) na ũwau ũngĩ wĩtawa Crohn's disease, methĩawa matonya kũkwatwa nĩ kanza ya mavĩndĩ.

5. Maũndũ amwe matonya kũtuma mũndũ awaa kanza: Maũndũ amwe matonya kũtuma mũndũ awaa kanza ta Lynch syndrome na familial adenomatous polyposis, nĩmatumaa mũndũ ethĩwa na ũwau ũsu.

6. Kũya lĩu ũte mũuke: Andũ ala maĩsaa lĩu wĩ na nyama mbingĩ na syĩndũ ingĩ ta nyama, matunda, nyũnyi, na mbeke, na ala maĩsaa lĩu ũte mũuke mwingĩ, nĩmakothaa kũkw'a nĩ kanza ya kĩthũi.

7. Ũkũũ mwingĩ: Mũndũ ũla wĩ na ũito mwingĩ kana wĩ na mwĩĩ mwingĩ mũno nũtonya kũkwatwa nĩ kanza ya kĩthũi.

8. Kwĩkala nthĩ: Mũndũ ũla ũtindĩaa kwĩkala nthĩ nũtonya kũkwata ũwau wa kanza ya kĩthũi.

9. Kũnyw'a sikala: Kũnyw'a sikala nĩkũtumaa mũndũ ethĩwa na ũwau wa kanza ya kĩthũi na mĩthemba ĩngĩ ya kanza.

10. Kũnyw'a ũkĩ mũno: Kũnyw'a ũkĩ mũno nĩkũtonya kũtuma mũndũ akwatwa nĩ kanza ya kĩthũi.

11. Ũwau wa mũthemba wa kelĩ wa sukalĩ: Andũ ala makwatĩtwe nĩ ũwau ũsu methĩawa matonya kũkwatwa nĩ kanza ya kĩthũi.

12. Andũ ma mbaĩ ingĩ: Andũ ala maumĩte mbaĩnĩ sya Africa na Amelika methĩawa matonya kũkwatwa nĩ kanza ya kĩthũi mũno kwĩ andũ ma mbaĩ ingĩ.

13. Kũiitwa na nzeve: Mũndũ nũtonya kũkwatwa nĩ ũwau wa kanza ya mavũi ethĩwa tene nĩwawaĩte kanza ĩngĩ ya ĩvĩndĩ kana ya kĩnyunyu.

14. Mowau amwe mũndũ ũsyaawa namo: Mowau amwe andũ masyaawa namo ta Lynch syndrome na familial adenomatous polyposis, nĩmatumaa mũndũ ethĩwa na ũwau wa kanza ya kĩthũi.

15. Kũsiw'a kũlika waonĩ, kũtilĩka waonĩ, na kũlika waonĩ wa T4: Maũndũ asu nĩmo matonya kũtuma mũndũ ethĩwa na kanza ya colon.

16. Maũndũ ala matonya kũtuma mũndũ awaa kanza: Maũndũ amwe matonya kũtuma mũndũ awaa kanza ta kũya mũno na kwĩkala ate kwĩtanĩthya, no matetheesye mũndũ ndakawae kanza ya kĩthũi.

17. Ĩka masoesi ũteũtĩĩa na ũya lĩu mũseo: Kwĩka masoesi ũteũtĩĩa na kũya lĩu wĩ na matunda maingĩ, mboka, na lĩu wa mĩthemba ĩngĩ no kũũtetheesye ndũkakwatwe nĩ kanza ya kĩthũi.

18. Kwĩthima: Kwĩthima mavinda kwa mavinda nĩ kana ũmanye ethĩwa wĩ na kanza ya kĩthũi kana ndetema, no kũũtetheesye kũmanya ũwau ũsu na kũũsiĩĩa ndũkese kũlika.

19. Maũndũ amwe matonya kũtuma mũndũ awaa ũwau ũsu: Maũndũ amwe matonya kũtuma mũndũ awaa ũwau ũsu nĩ ta ũkũũ, ũko, na ethĩwa ve andũ ma mũsyĩ maĩ na ũwau ũsu, na tũitonya kũmasiĩĩa.

20. Maũndũ amwe matonya kũtuma mũndũ akwatwa nĩ kanza ya colon nĩ ta: kwĩthĩwa ate na kĩthito kya mwĩĩ, kũya mũno, kũnyw'a sikala, na kũnyw'a ũkĩ mũno.

21. Kwĩthima: Kwĩthima mavinda kwa mavinda nĩ kana ũmanye ethĩwa wĩ na kanza ya kĩthũi kana ndetema, no kũũtetheesye kũmanya ũwau ũsu na kũũsiĩĩa ndũkese kũlika.

22. Kũmanya mũndũ e na kanza tene: Mũndũ e na kanza ya kĩthũi na wamanyĩka tene no avonoke.

23. Maũndũ ala matonya kũtuma mũndũ ethĩwa na ũwau wĩtawa metachronous neoplasms: Kwa ngelekany'o, mũndũ eethĩwa na ũwau wĩtawa colon cancer, na ethĩwa e na ũwau wĩtawa synchronous high-risk adenomas, na ethĩwa e na ũwau wĩtawa hypertension, nũtonya kwĩthĩwa na ũwau wĩtawa metachronous neoplasms.

24. Nzĩa sya kwĩthima: Ve nzĩa syĩ kĩvathũkany'o sya kwĩthima mũndũ ethĩwa e na kanza ya kĩthũi. Nzĩa imwe nĩ kwa kũmũtũmĩa mũndũ mwene kwĩka ũkunĩkĩli wa nthakame ĩla yĩ kĩthũi, kana kwa kũmũtũmĩa masinĩ ya sigmoidoscopy.

25. Maũndũ ala matonya kũtuma ĩvu yĩtĩka: Kũnyw'a sikala na kũthĩnw'a kwa ĩvinda ĩasa nĩ maũndũ matonya kũtuma ĩvu yĩtĩka ngalĩ ya kw'oko kwa aũme ĩla mũndũ wathĩnzwa ĩvu ya kw'oko kwa aũme.

26. Maũndũ ala matonya kwĩkĩka mũndũ eethĩwa na ũwau wa kanza: Vai kĩvathũkany'o kĩnene katĩ wa ala maĩ na ũwau ũsu na ala mataĩ naw'o.

27. Maũndũ ala matonya kũtuma mũndũ ethĩwa na kanza ya kĩthũi: Ũkũũ, ũasa wa kĩnyunyu, kũtũmĩa ndawa sya kũsiĩĩa na kũkua ĩvu, myaka mingĩ ya kũnyw'a sikala, ũwau wa mavĩndĩ, kũthelelwa nĩ nthakame, kũnoa mũno, ũwau wa sukalĩ, kũtũmĩa ndawa nini sya kũvosya, na kũtilwa kĩthũi.

28. Maũndũ ala matonya kũtuma mũndũ akw'a Jiashan County,

['Maũndũ ma kwongeleela']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Hartz A, He T, Ross JJ: Risk factors for colon cancer in 150,912 postmenopausal women. Cancer Causes Control. 2012, 23 (10): 1599-605.

Wang X, Lei T, Ma X: [Colon cancer risk factors in Jiashan county, Zhejiang province, the highest incidence area in China]. Zhonghua Zhong Liu Za Zhi. 2001, 23 (6): 480-2.

Hatano S, Ishida H, Ishibashi K, Kumamoto K, Haga N, Miura I: Identification of risk factors for recurrence in high-risk stage II colon cancer. Int Surg. , 98 (2): 114-21.

Platz EA, Willett WC, Colditz GA, Rimm EB, Spiegelman D, Giovannucci E: Proportion of colon cancer risk that might be preventable in a cohort of middle-aged US men. Cancer Causes Control. 2000, 11 (7): 579-88.

Nam K, Shin JE: Risk factors of advanced metachronous neoplasms in surveillance after colon cancer resection. Korean J Intern Med. 2021, 36 (2): 305-312.

Kwak HD, Kim SH, Kang DW, Baek SJ, Kwak JM, Kim J: Risk Factors and Oncologic Outcomes of Anastomosis Leakage After Laparoscopic Right Colectomy. Surg Laparosc Endosc Percutan Tech. 2017, 27 (6): 440-444.

['Ũtao:']

["Kĩsese kĩĩ kĩseũvĩtw'e kwondũ wa kũmanyĩsya na kũtetheesya andũ, ĩndĩ ti kũnengane motao ma ũiiti kana ũtethyo ũngĩ."]

['Ũvoo ũla wĩ vo ndwaĩle kũtũmĩwa kũĩkĩĩthya kana mũndũ e na ũwau mũna, na ala mekwenda ũtao wa ũiiti maĩle kũneena na ndakĩtalĩ.']

["Kwa ngelekany'o, ĩla mũndũ wakũlya ĩkũlyo yĩ na namba, no amanye kana mũndũ ũsu e na ũwau mũna."]

['Kĩla ĩvinda neena na ndakĩtalĩ waku kana mũndũ ũngĩ ũsomeete maũndũ ma ũiiti. Ndũkaatate kũlea kana kũkua ĩvinda ũimũkũlya ũtao aĩ nũndũ wa maũndũ amwe wasoma Kĩsesenĩ kĩĩ. Ethĩwa wĩona ta wĩ na thĩna wa mĩtũkĩ, neena na namba ya 911 kana ũthi sivitalĩ ya mĩtũkĩ ĩla yĩ vakuvĩ.']

['Ũtao:']

['The Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the DMCA) nĩyaĩtye kana ala me na ũthasyo wa kumĩthya syĩndũ ila syĩ Indanetinĩ nĩmaĩle kũtata ũndũ matonya nĩ kana maĩkĩĩthye kana syĩndũ ila mekumĩthya nĩsyavĩnga mĩao ya nthĩ ya Amelika.']

['Ethĩwa wĩ na mũĩkĩĩo kana ũvoo ũla wĩ kĩsesenĩ kitũ kana nthĩnĩ wa syĩndũ ila tumasya nũvĩtĩsye mĩao yaku, no ũtũtũmĩe valũa ũũtwĩĩte kana no ũtũsiĩĩe tũikamĩsome.']

['No ũtũmĩe valũa ũũ (sisya vala vaandĩkĩtwe "Ndũkatũmĩe valũa ũũ") ũnyaĩĩkya ũvoo.']

["Mĩao ya DMCA yaĩtye kana no nginya ũvoo ũla ũũtũmĩa kũtũtavya kana ve kĩndũ kĩna kĩnavĩnga mĩao ya kumĩthya syĩndũ wĩthĩwe na ũvoo ũũ: (1) ũvoo ĩũlũ wa syĩndũ ila iwetetwe kana nĩsyo ivĩngĩĩsiwe nĩ mĩao ĩsu; (2) ũvoo ĩũlũ wa syĩndũ ila iwetetwe kana nĩsyo ivĩngĩĩsiwe nĩ mĩao ĩsu na ũvoo ũtonya kũtũtetheesya kũmanya vala syĩndũ isu syĩ; (3) ũndũ ũtonya kũtũtavya ũndũ ũtonya kũtũtavya ũndũ ũtonya kũũkũlya, ta vala wĩkalaa, namba yaku ya simũ, na valũa waku wa simũ; (4) ũĩkĩĩthyo ũkwonany'a kana wĩ na mũĩkĩĩo kana syĩndũ ila iwetetwe vau iyĩtĩkĩlĩtw'e nĩ ũla wĩ na ũthasyo wa kũseũvya syĩndũ, kana nĩ mũũngamĩi wasyo, kana nĩ mĩao ĩngĩ."]

["(5) ũĩkĩĩthyo kuma kwaku, ũla ũandĩkĩte ũikĩa ũkũsĩ ũte wa w'o, kana ũvoo ũla wĩ nthĩnĩ wa livoti nĩ wa w'o na kana wĩ na ũkũmũ wa kũũngamĩa maũndũ ala mawetwa nĩ ũla ũkũũmĩw'a;"]

['Na (6) saii ya mwene syĩndũ kana mũndũ ũla ũnengetwe ũkũmũ wa kwĩka maũndũ kwondũ wake.']

['Ethĩwa ndũwetete maũndũ asu onthe, nũtonya kũema kwĩtetea.']

['Ũndũ ũtonya kũneena namo']

['Tũmĩa email ũtũkũlye kana ũnenge ũtao.']

What are the risk factors for colon cancer?

1. Age: The risk of developing colon cancer increases with age, with most cases occurring in people over the age of 50.

2. Personal history of polyps or colon cancer: If you have had colon polyps or colon cancer before, you are at a higher risk of developing it again.

3. Family history of colon cancer: Having a family history of colon cancer increases your risk of developing the disease.

4. Inflammatory bowel disease: Chronic conditions such as ulcerative colitis and Crohn's disease increase the risk of colon cancer.

5. Genetic syndromes: Certain inherited genetic syndromes, such as Lynch syndrome and familial adenomatous polyposis, increase the risk of colon cancer.

6. Diet: A diet high in red and processed meats, and low in fruits, vegetables, and whole grains, has been linked to an increased risk of colon cancer.

7. Obesity: Being overweight or obese increases the risk of colon cancer.

8. Physical inactivity: A sedentary lifestyle is associated with an increased risk of colon cancer.

9. Smoking: Smoking increases the risk of colon cancer, as well as other types of cancer.

10. Alcohol consumption: Heavy alcohol use has been linked to an increased risk of colon cancer.

11. Type 2 diabetes: People with type 2 diabetes have a higher risk of developing colon cancer.

12. Ethnicity: African Americans have a higher risk of colon cancer than other ethnic groups.

13. Radiation therapy: Previous radiation therapy for other cancers in the abdomen or pelvis may increase the risk of colon cancer.

14. Inherited syndromes: Certain inherited syndromes, such as Lynch syndrome and familial adenomatous polyposis, increase the risk of colon cancer.

15. Obstruction, perforation, and T4-level invasion: These factors have been identified as independent risk factors for colon cancer.

16. Controllable risk factors: Some risk factors, such as diet and lifestyle, can be controlled to reduce the risk of colon cancer.

17. Regular exercise and a healthy diet: Engaging in regular physical activity and eating a diet rich in fruits, vegetables, and whole grains can help reduce the risk of colon cancer.

18. Screening: Regular screening for colon cancer, such as colonoscopy, can help detect and prevent the disease.

19. Risk factors beyond our control: Some risk factors, such as age, race, and family history, cannot be changed, but being aware of them can help with early detection and treatment.

20. Lifestyle risk factors: Being physically inactive, overweight, smoking, and heavy alcohol consumption are lifestyle risk factors that can increase the risk of colon cancer.

21. Screening: Regular screening for colon cancer, such as colonoscopy, can help detect and prevent the disease.

22. Early detection: Early detection of colon cancer through screening can improve survival rates.

23. Risk factors for advanced metachronous neoplasms: Distal colon cancer, synchronous high-risk adenomas, and hypertension may increase the risk of advanced metachronous neoplasms during surveillance after colon cancer resection.

24. Screening options: There are various screening options for colon cancer, including fecal occult blood tests, sigmoidoscopy, and virtual colonoscopy.

25. Risk factors for anastomosis leakage: Smoking and long operating time are risk factors for right-side colon anastomosis leakage after laparoscopic right colectomy.

26. Oncologic outcomes: There are no significant differences in local recurrence, overall survival, or cancer-specific survival between patients with and without anastomosis leakage after laparoscopic right colectomy.

27. Risk factors for colon cancer in postmenopausal women: Age, waist girth, use of hormone therapy, years smoked, arthritis, lower hematocrit levels, fatigue, diabetes, less use of sleep medication, and cholecystectomy are risk factors for colon cancer in postmenopausal women.

28. Risk factors in Jiashan County,

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