What is prognosis of Alzheimer?

['Welisi hɔɔlʋʋ kʋnɛ']

Kʋdɔŋ ŋgʋ payaɣ se Alzheimer yɔ, kɩ-kʋdɔŋ piye lɛ nɖɩ?

Kʋdɔŋ ŋgʋ kɩɖɛɣ ɛyaa nɛ kɩɖɛɣ-wɛ ɖɔɖɔ nɛ paatasɩɣ-kʋ naʋ.

Paa anɩ ɛ-kʋdɔŋ ɛɛɖɛɣnɩ ɛzɩdaa kɛlɛʋ, ɛlɛ kɩɖɛɣ nɛ kɩkpaɣ ɖoŋ kɩkpaʋ nɛ kɩkɔŋnɩ lɛɣtʋ nɛ tomnaɣ taa alaafɩya pɛ-ɛjandʋ.

Kʋdɔŋ ŋgʋ kɩɖɛɣ lɛ, ɛyaa wɛɣnɩ maɣzɩm taa kʋdɔmɩŋ, paatasɩɣ yɔɔdʋʋ camɩyɛ, paatasɩɣ wɛnʋʋ lɩmaɣza kɩbana, paatasɩɣ wɛnʋʋ wɛtʋ kɩbandʋ nɛ pacakɩ wezuu kɩdɛkɛdʋʋ.

Pɩtɩla alɩwaatʋ ndʋ tɩ-taa lɛ, paatasɩɣ pɩzʋʋ nɛ pɔcɔnɩ pa-tɩ yɔɔ nɛ pɩpɔzʋʋ se nɔɔyʋ ɛsɩnɩ-wɛ.

Kʊdɔŋ ŋgʊ kɩ-tɛ ɛyaa kɩla ɖɔʊ nɛ pacakɩ wezuu ɛzɩ pɩnzɩ 8 yaa 10 yɔ ɛlɛ pɩlɩna ɛyʊ wɛtʊ, ɛ-alaafɩya nɛ hɔɔlɩŋ lɛɛŋ yɔɔ.

Paa kʋdɔŋ ŋgʋ kɩ-taa ɛɛpɩzɩɣ nɛ ɛwaa yɔ, kɩ-kʋdɔmɩŋ waʋ nʋmɔŋ nɩɩyɩ pɩzɩɣ ɩsɩnɩ-ɩ nɛ ɛwɛɛnɩ lɩmaɣza kɩbana kʋdɔŋ ŋgʋ kɩ-yɔɔ nɛ e-wezuu caɣʋ wɛɛ ɖeu nɛ pɩkɩlɩ.

['Takayɩhatʋ ndʋ tɩtamsɩna \\ yɔ']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Kaldjian LC: Survival versus prognosis in Alzheimer disease. Ann Intern Med. 2004, 141 (7): 575; author reply 575.

Mayeux R, Stern Y, Sano M: Heterogeneity and prognosis in dementia of the Alzheimer type. Bull Clin Neurosci. 1985, 50 (): 7-10.

DeKosky ST, Golde T: Cerebrospinal Biomarkers in Alzheimer Disease-Potential Roles as Markers of Prognosis and Neuroplasticity. JAMA Neurol. 2016, 73 (5): 508-10.

Yaffe K: Treatment of Alzheimer disease and prognosis of dementia: time to translate research to results. JAMA. 2010, 304 (17): 1952-3.

Zhu B, Chen X, Li W, Zhou D: Effect of Alzheimer Disease on Prognosis of Intensive Care Unit (ICU) Patients: A Propensity Score Matching Analysis. Med Sci Monit. 2022, 28 (): e935397.

Malpetti M, Joie R, Rabinovici GD: Tau Beats Amyloid in Predicting Brain Atrophy in Alzheimer Disease: Implications for Prognosis and Clinical Trials. J Nucl Med. 2022, 63 (6): 830-832.

Schaeffer EL, Figueiro M, Gattaz WF: Insights into Alzheimer disease pathogenesis from studies in transgenic animal models. Clinics (Sao Paulo). 2011, 66 Suppl 1 (): 45-54.

Bhagwat N, Pipitone J, Voineskos AN, Chakravarty MM: An artificial neural network model for clinical score prediction in Alzheimer disease using structural neuroimaging measures J Psychiatry Neurosci. 2019, 44 (4): 246-260.

Vermunt L, van Paasen AJL, Teunissen CE, Scheltens P, Visser PJ, Tijms BM: Alzheimer disease biomarkers may aid in the prognosis of MCI cases initially reverted to normal. Neurology. 2019, 92 (23): e2699-e2705.

Raji MA, Brady SR: Mirtazapine for treatment of depression and comorbidities in Alzheimer disease. Ann Pharmacother. 2001, 35 (9): 1024-7.

['Tɔm ndʋ tɩ-yɔɔ ɖitisiɣ yɔ: ɖɔkɔtɔ']

['Ye ŋwobi intɛrnɛɛtɩ lone ɖɩnɛ ɖɩ-yɔɔ yɔ, ŋpɩzɩɣ nɛ ŋkpɛlɩkɩ tɔm sakɩyɛ ɖɩ-yɔɔ.']

['Pɩtɩpɔzɩ se patɩŋnɩ tɔm ndʋ pama takayaɣ kanɛ ka-taa yɔ tɩ-yɔɔ nɛ pañɩnɩ kʋdɔŋ nakʋyʋ yaa pawaa-kʋ.']

['Tɩlɩ camɩyɛ se ordinatɛɛrɩ yɔɔ tɔm ndʋ pɔpɔzʋʋ yɔ, tɩ-yɔɔ cosuu wɛ kaɖɛ, kɔzɩ kɔzɩ alɩwaatʋ ndʋ tɩ-taa pɔpɔzʋʋ tɔm natʋyʋ nɛ tɩ-taa tɔm pee tɩɖɔɔ yɔ.']

['Paa ɛzɩmtaa lɛ, pɔzɩ lɔŋ tasʋʋ fɛɖʋ weyi ɛsɩm ñɔ-yɔɔ tɔm sakɩyɛ yɔ nɛ ɛyɔɔdɩ-ŋ kʋdɔŋ ŋgʋ ŋwɛna yɔ kɩ-tɔm. Taayele nɛ lɔŋ tasʋʋ mbʋ fɛɖʋ ɛnʋ ɛha-ŋ yɔ, pɩɖɛɛ ñɔ-yɔɔ yaa ŋyele-pʋ ñɩnʋʋ mbʋ pʋyɔɔ yɔ ŋkalɩ tɔm natʋyʋ intɛrnɛɛtɩ lone ɖɩnɛ ɖɩ-yɔɔ. Ye ŋmaɣzɩɣ se pɩwɩɣ-ŋ yɔ, yaa ɛyaa 911 yaa ŋwolo ɖɔkɔtɔ ŋgʋ kɩñɔtɩnɩ-ŋ yɔ kɩ-taa kpaagbaa.']

['Takayɩhatʋ ndʋ tɩtamsɩna \\ Paɣtʋ \\ yɔ']

['Digital Millennium Copyright Act 1998 ñɩŋgʋ, 17 U.S.C. § 512 (DMCA) haɣ waɖɛ mba pɛwɛnɩ waɖɛ se pala tʋmɩyɛ intɛrnɛɛtɩ yɔɔ yɔ se pala mbʋ pɩkaɖɩɣnɩ waɖɛ nɖɩ pɛwɛna Etaazuunii ɛjaɖɛ taa yɔ.']

['Ye ŋmaɣzɩɣ se tɔm natʋyʋ yaa wonuu nakʋyʋ yɔɔ pama tɔm intɛrnɛɛtɩ lone ɖɩnɛ ɖɩ-yɔɔ yaa intɛrnɛɛtɩ lone ɖɩnɛ ɖɩ-yɔɔ nɛ pɩkaɖɩɣnɩ ña-paɣtʋ yɔ, ña-maɣmaɣ yaa weyi ɛsɩɣ-ŋ tʋmɩyɛ yɔ, ŋpɩzɩɣ nɛ ŋtiyini-ɖʋ takayaɣ nɛ ŋpɔzɩ se ɖɩlɩzɩ tɔm ndʋ yaa wonuu ŋgʋ yaa ɖitaayele nɛ nɔɔyʋ tɩlɩ-kʋ.']

['Pɩwɛɛ se pama takayaɣ nɛ petiyini ordinatɛɛrɩ yɔɔ.']

['DMCA paɣtʋ pɔzʋʋ se ye ŋnawa se nɔɔyʋ tɩma takayaɣ nakɛyɛ yɔ, ŋma tɔm tʋnɛ: (1) takayaɣ ŋga ŋnawa se nɔɔyʋ tɩma-kɛ yɔ kɔ-yɔɔ tɔm; (2) takayaɣ ŋga kɔ-yɔɔ pamawa se nɔɔyʋ tɩma takayaɣ nakɛyɛ yɔ kɔ-yɔɔ tɔm nɛ tɔm ndʋ tɩsɩɣnɩ-ɖʋ se ɖɩtɩlɩ ɖenɖe ŋnaɣ takayaɣ ŋga yɔ; (3) ña-hɩɖɛ, kaŋgalaafu mayaɣ nɛ intɛrnɛɛtɩ mayaɣ; (4) ŋyɔɔdɩ kpayɩ se ŋwɛnɩ tisuu se takayaɣ ŋga ŋnawa se nɔɔyʋ tɩma-kɛ yɔ, pɩtɩkɛ weyi ɛtɩnɩ takayaɣ ŋga yɔ ɛ-maɣmaɣ ɛlɩzɩnɩ-kɛ, yaa ɛ-tʋmlaɖʋ nɔɔyʋ lɩzɩnɩ-kɛ, yaa se paɣtʋ natʋyʋ ɛɛhaɣ nʋmɔʋ se palabɩnɩ-kɛ tʋmɩyɛ.']

['(5) Ye ŋlabɩ mbʋ yɔ, ŋpɩzɩɣ nɛ ŋcɛtɩnɩ ñɔ-tɔm yɔɔ nɛ ŋyɔɔdɩ se tɔm ndʋ pama takayaɣ ŋga ka-taa yɔ tɩkɛ toovenim nɛ ŋwɛnɩ waɖɛ se ŋlʋ nɛ ŋwa mba payʋsʋʋ se pɛwɛɛkɩ ña-takayaɣ yɔ.']

['Nɛ (6) ye nɔɔyʋ ɛtɩnɩ takayaɣ nakɛyɛ yɔɔ tɔm yɔ, pɩwɛɛ se ɛñɩɣ nesi takayaɣ ŋga kɔ-yɔɔ.']

['Ye patɩyɔɔdɩ tɔm ndʋ tɩ-tɩŋa yɔ, pɩpɩzɩɣ nɛ pɩkɔnɩ tɔm hʋʋ kaɖɛ.']

['Ɛyʋ weyi ŋkatɩɣ yɔ']

['Ye ŋwɛnɩ tɔm natʋyʋ yaa ŋñɩnɩɣ se ŋtasɩ tɔm natʋyʋ yɔ, ɖitendi-ŋ ma-ɖʋ takayaɣ.']

What is prognosis of alzheimer?

The prognosis of Alzheimer's disease is generally poor, as it is a progressive and degenerative condition with no known cure.

The rate of progression varies from person to person, but the disease typically worsens over time, leading to a decline in cognitive and physical abilities.

As the disease progresses, individuals may experience memory loss, difficulty with language and communication, disorientation, and changes in mood and behavior.

Eventually, they may become unable to care for themselves and require full-time assistance.

The average life expectancy after diagnosis is around 8-10 years, but this can vary widely depending on the individual's age, overall health, and other factors.

While there is no cure, treatments and therapies can help manage symptoms and improve quality of life for those with Alzheimer's disease.

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