What causes Colon cancer?

['Wande ruwu adǝ fanne']

Abi kwasa kansa suronbe suwudin?

Colon cancer, daji kuru colorectal cancer lan notǝna dǝ, shima cell donyi suro lan wurajin ma.

Dalil kwasa kansa surobedǝ notǝnyi, amma awowa kada tajirwa kwasa shima dǝga suwudin.

Sandi anyiye suronzan:

1. Saa: Tajirwa kansa surobbedǝ saa ngǝwu'a kozǝnaro wurajin, kambowo so kam 50 kozǝnadǝn fǝlanzǝyin.

2. Gargam yallabe: Gargam kamye au yallabe kansa surobye au polypsye mbeji dә tajirwa kwasa shima dәye suwudinye tərana.

3. Kwasa donyi waratatin ma: Kwasa donyi waratatin ma geneticya ye, alaman familial adenomatous polyposis (FAP) a hereditary non-polyposis colorectal cancer (HNPCC), sandima colonic cancer ro waljin.

4. Kәnәngatәbe: Kәmbu buye buye-a dabbaye-a, zauro kәmbun zuwunama, tafa, tafa kuru mbal zauro kәnzabe-a dә kasuwa kansa surobedәa suwudin.

5. Kwasa suronbe kǝnzǝlibe: Kwasa suronbe kǝnzǝlibe loktu kuruwu gozǝnama, jili ulcerative colitis-a Crohn's disease-a, tajirwa kwasa kansa suronbe fulujin.

6. Kwasa kansabe jili 2 ye: Am kwasa kansabe jili 2 soye sandiya kwasa kansa surobero gotabe mbeji.

7. Radiation therapy: Radiation therapy kwasa kansabe gade suro surimbabe lan risku kwasa kansa surobedǝa suwudin.

8. Nǝm gade lawuno be: Kam lardǝ African Americaye dǝ sandiya kwasa kansa kǝrǝnbe suwondin futu la gade yeyi ro.

Notǝ dǝ zauro mǝradǝtǝna fal au awaa kozǝna anyi sammaso tajirwa dǝwo kam dǝga kansa kǝrǝnbe suwudin ma wo, kuru kam laa dǝwo kansa kǝrǝnbe suwudin dǝ tajirwa notǝnyi.

Ngǝlaro kulashi kǝndobe-a tinyi-a dǝ ye kansa kǝrǝnbe-a ngǝlaro notǝro banajin au baditǝ badiyaram lan notǝ sa shima dǝ kurun tuwondin ma.

['Wutəgə']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.

Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.

Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.

Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.

Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.

Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.

Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.

['Kәlanzәma ro cistәgә: liita']

['Websayit adә ilmu matәbe-a bayan matәbe bas nankaro cedo kuru shawari liyitabe au cidawa cidawu liyitabe diobe gәnyi.']

['Bayanwa yitagattәgәna so dә kwasa laa au kwasa laa asutu au kurun dio ro faidatәmba, kuru am doni shawaria liyitaye mazayin so dә dokta lasisatәna ro manatә saadin.']

['Martәne netәram kәrәnbe do korowa dә ro jawawu suwudin dә, taganasmaro kalkal gәnyi sa lamba isәna dәn. Misallo, nәm nguwu am doni kwasa laa taganasbe shiro asuzana ma.']

["Sambi so ro shawari kam litari nәm au kam gade nasha nәlewabe nozәna ma ye la'atar ro matәne. Shawari kam litaribe nozәna ma ro tәmmaro hangal gәnyi gәnane au sha matә lan loktu gozәnyi awo laa website adәn kәrәnәmma yen. Nyiye kurun nәlewabe batәrammin maa, talfon 911 lan buwoze au njim liwalabe karungu ma ro lenәme. Alaka nәlewa-a dondibe ba ma tuwandin web site adә men au shilan faidatәmen. BioMedLib-a cidawunzә-a, au kam do web site adә ro banazәyin-aye, affima bayanzәna au manazәna ma sadimba, bayanwa suro adәben tuwandin au shilan faidatәmen."]

['Kәlanzәma ro cistәgә: hakku']

['Digital Millennium Copyright Act 1998 17 U.S.C. § 512 (DMCA) dəye am doni hakku kakkadə baksanasodəga nzəliwo sədinma kəla awo lardə U.S.be kərma kakkadə baksəna dəga internet lan fəletəma nzəliwo nankaro.']

['Suro nәm kәla nәm ngәla yen awo laa au kare laa kәla intanetndeyen au cidawandeyen mbejiye hakku nәm kakkadi ruotәbe nyiro kalzәna ma ye mbeji maa, nyi (au wakkilnәm) andero watiya zuwune awo au kare dә tutuluwu, au na dәro nazәgә dә tutuluwu.']

["Zande so dә ruwo lan zuzaiya, email men (adәretәm emailye dә nasha 'Lam'atarro manәmin)"]

['DMCA ye məradənzə bayan kəla nzətkawo kərmaabedəbe bayanwa anyi surodən mbejiro: (1) bayan kəla cida nzətkawobe dunonzə dunonzə kaltəgəbe dunonzə kaltəgəbe; (2) bayan kəla awoa zortəbe dunonzə kaltəgəbe dunonzə kuru bayan kəzəkə andeya səkə awoadəga fandəmin; (3) bayan kəlanəm lamba fantəbe, suro nzəranəm-a, lamba telehonbe-a kuru email-be-a; (4) bayan kəlanəmbe kəla nyiye tawatkənənde kəla awoa zortəbe dunonzə kaltəgəbe dunonzəye dunonzəye səkə au wakilinzəye, au shara laabe səkə; ']

['(5) bayan nyima, kalima jirebero, ruwotәgәna, bayan suro watiyade dә kalkalzәna kuru nyiye hakku kәlanzәbe hakkuwa ləbtәma soye warmatәgәbe dәga nonәmma;']

['kuru (6) mukko dunowa au lantarkibe hakkiwa ləbtamabe au kam laaye wakil zəben cida sədənabe. ']

['Bayanna samibe samma kәltәgә nyiye mowonzә zәktә lamar buruwunәmye gәrәmin.']

['Lǝtǝram']

['Martәne ande ro watiya emailye lan koro/shawari laa manane.']

What causes colon cancer?

Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.

The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.

These include:

1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.

2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.

3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.

4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.

5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.

6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.

7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.

8. Race: African Americans have a higher risk of developing colon cancer than other races.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.

Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.

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