Inki mutindu bo kesengumunaka maladi ya Alzheimer?
Bo kesadilaka bametode mingi sambu na kuzaba kana muntu kele ti maladi ya Alzheimer, mu mbandu, bo kesalaka ekzame ya mbote ya kimunganga, ekzame ya mayele ya kuyindula mpi ya maladi ya butomfu, ekzame ya butomfu ya ntu, mpi bo ketadilaka mambu yankaka yina lenda sala nde muntu kuvanda ti maladi yango.
1. Kusosa lusansu: Munganga takwenda kutala nitu na nge mpi yandi tatadila mambu yonso ya metala maladi na nge sambu na kuzaba kana kele ti mambu yankaka ya lenda sala nde nge vila mambu to nge zaba ve mambu mbote, mu mbandu maladi ya thyroïde, kukonda vitamine, to tumore ya butomfu.
2. Bametode ya kuzaba mambu mpi ya kuzaba mabanza ya muntu: Metode yai ketadilaka mambu ya muntu keyibuka, ndinga, mutindu ya kuyidika makambu, mpi bisalu yankaka ya kuzaba mambu sambu na kuzaba kiteso ya mpasi ya muntu kewa mpi sambu na kuzaba luswaswanu na kati ya kukonda kuyibuka mambu ya mbote yina kekatukaka na kimununu ti maladi ya ntu.
3. Bafoto ya butomfu: Bafoto ya butomfu ya bo kebingaka nde résonance magnétique (IRM) to tomographie par ordinateur (TC) lenda sadisa na kuzaba bansoba yina kebasikaka na butomfu yina lenda monisa nde muntu kele ti maladi ya Alzheimer.
Bo lenda sadila mpi tomographie par émission de positons (TEP) sambu na kuzaba kiteso ya baproteine ya nkaka yina ke salaka nde muntu kubela maladi ya Alzheimer.
4. Kusosa menga: Bansosa ya bo mesala ntama mingi ve memonisa nde ekzame yankaka ya menga lenda sadisa na kuzaba maladi ya Alzheimer na kutadilaka kiteso ya baproteine to ya bima yankaka yina kemonisaka maladi yango.
5. Mutindu ya kuzaba kana muntu kele ti maladi ya Alzheimer to ve: Sambu kele ve ti metode mosi ya sikisiki ya kuzaba kana muntu kele ti maladi ya Alzheimer to ve, mbala mingi bo kesosaka kuzaba kana maladi yango mekatukaka na bima yankaka yina lenda sala nde muntu kubela maladi ya ntu.
Yo kele mfunu na kuzaba nde bo lenda zaba kana muntu kele ti maladi ya Alzheimer kaka kana bo me tala butomfu na yandi na nima ya lufwa.
Kansi, metode ya bubu yai ya kuzaba maladi lenda sadisa muntu na kuzaba maladi na yandi mbote ntangu yandi kele na luzingu.
Kuzaba maladi na ntwala kele mfunu sambu na kuyantika lusansu mpi kudibongisa sambu na bilumbu kekwisa.
Liu SS, Zhu SQ: [Correlation between Alzheimer disease and cataract]. Zhonghua Yan Ke Za Zhi. 2017, 53 (4): 314-316.
Gauthier S: Practical guidelines for the antemortem diagnosis of senile dementia of the Alzheimer type. Prog Neuropsychopharmacol Biol Psychiatry. 1985, 9 (5-6): 491-5.
Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.
[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.
Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.
Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.
Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.
Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.
Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.
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['Bo fwete sadila ve bansangu yina bo kepesa sambu na kuzaba to kubelula maladi mosi buna, mpi bantu yina kesosa bandongisila ya kimunganga fwete solula ti munganga yina kele ti nswa ya kusala kisalu yina.']
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['Sosa ntangu yonso bandongisila ya munganga to ya muntu ya nkaka ya me zaba kisalu ya kusansa bantu sambu na maladi na nge. Kuvila ve bandongisila ya munganga to kusukinina ve na kusosa yo sambu na mambu ya nge me tanga na site Internet yai. Kana nge ke yindula nde nge kele ti maladi ya ngolo, binga 911 to kwenda nswalu na lupitalu ya me finama. Site Internet yai to mutindu nge ke sadila yo ke sala ve nde nge kuma nduku ya munganga to nkengi ya maladi.']
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['Kana nge ke mona nde mambu ya nge ke tanga na site Internet na beto to na baservice na beto ke fwa banswa na nge, nge (to muntu yina ke twadisaka nge) lenda tindila beto mukanda sambu na kulomba nde beto katula yo to kukanga nzila na nge ya kusadila yo.']
['Bo fwete tinda bansangu na mukanda na nzila ya email (tala na "Kutuba na beto" sambu na kuzaba adresi ya email).']
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['5) na nima ya kupesa nzikisa na mukanda yina nge me sonika, nge fwete ndima nde mambu yina nge me tuba kele ya kieleka mpi nde nge kele ti nswa ya kusadila banswa yina bo me bebisa.']
['mpi (6) kidimbu ya muntu yina kele ti nswa ya kubasisa yo to ya muntu yina kele ti nswa ya kusala mambu na zina na yandi. ']
['Kana nge pesa ve bansangu yai yonso, yo lenda sala nde bo sala ve mambu nswalu.']
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['Beno tindila beto email kana beno kele na ngyufula to ngindu.']
How is alzheimer diagnosed?
Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.
1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.
2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.
3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.
Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.
4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.
5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.
It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.
However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.
Early diagnosis is important for starting treatment and planning for the future.
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