Mpo na koyeba maladi ya Alzheimer, esɛngaka mayele ndenge na ndenge, na ndakisa kotalela malamumalamu nzoto ya moto, kosala ekzamɛ ya bɔɔngɔ, mpe kotalela makambo mosusu oyo ekoki kosala ete moto azala na maladi yango.
1. Kotala monganga: Monganga akosala ekzamɛ ya nzoto mpe akoyeba makambo nyonso ya maladi na ye mpo na koyeba soki ezali na makambo mosusu oyo ekoki kosala ete abosana to ayeba lisusu makambo mingi te, na ndakisa maladi ya thyroïde, kozanga vitamini to kanser ya bɔɔngɔ.
2. Komeka makoki ya kokanisa mpe ya bɔɔngɔ: Komeka yango esalisaka moto ayeba makambo oyo abosanaka te, ayeba koloba, ndenge ya kosilisa mikakatano, mpe ayeba makambo mosusu mpo na koyeba soki azali na makoki ya kokanisa mingi to te mpe ayeba kokesenisa maladi ya motó na maladi ya motó oyo eutaka na bobange.
3. Bililingi ya bɔɔngɔ́: Bililingi ya résonance magnétique (IRM) to tomographie par ordinateur (CT) ekoki kosalisa na koyeba mbongwana ya bɔɔngɔ́ oyo ekoki komonisa ete moto azali na maladi ya Alzheimer.
Tómographie par émission de positons (TEP) ekoki mpe kosalisa mpo na koyeba soki proteini moko oyo esalaka ete moto abɛla maladi ya Alzheimer ezali mingi to te.
4. Kotala makila: Bolukiluki oyo euti kosalema kala mingi te emonisi ete baekzame mosusu ya makila ekoki kosalisa mpo na koyeba maladi ya Alzheimer na kotaleláká proteini to biomarqueur oyo emonisaka maladi yango.
5. Ndenge ya koyeba maladi yango: Lokola ezali na ekzamɛ moko te oyo ekoki kosalisa moto ayeba soki azali na maladi ya Alzheimer, mbala mingi mpo na koyeba maladi yango esɛngaka koyeba makambo mosusu oyo ekoki kosala ete moto akóma na maladi yango.
Ezali na ntina koyeba ete maladi ya Alzheimer ekoki koyebama kaka nsima ya liwa na nzela ya ekzame ya misisa ya bɔɔngɔ.
Kasi, mayele ya sika ya kosala baekzame ekoki kosalisa moto ayeba maladi na ye malamu ntango azali naino na bomoi.
Koyeba maladi yango noki ezali na ntina mpo na kobanda kosalisa yango mpe komibongisa mpo na mikolo ezali koya.
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Gauthier S: Practical guidelines for the antemortem diagnosis of senile dementia of the Alzheimer type. Prog Neuropsychopharmacol Biol Psychiatry. 1985, 9 (5-6): 491-5.
Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.
[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.
Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.
Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.
Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.
Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.
Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.
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['Tosengi na yo oyeba ete réseau neuronal oyo epesaka biyano na mituna, ezalaka mpenza malamu te soki ezali na makambo ya mituya. Na ndakisa, motango ya bato oyo bazali na maladi moko boye.']
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How is alzheimer diagnosed?
Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.
1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.
2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.
3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.
Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.
4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.
5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.
It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.
However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.
Early diagnosis is important for starting treatment and planning for the future.
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