Maladi ya Alzheimer ezali maladi ya neurodegenerative oyo esalaka ete bɔɔngɔ ebeba, mpe esalaka ete moto abosana makambo, ayeba lisusu makambo mingi te, mpe bizaleli na ye ebongwana.
Ntina mpenza oyo epesaka maladi ya Alzheimer eyebani mpenza te, kasi bakanisaka ete ezali mpo na makambo ndenge na ndenge oyo moto abotamaka na yango, esika afandi, mpe lolenge ya bomoi oyo azali na yango.
Makambo mosusu oyo ekoki kosala ete moto akóma na maladi ya Alzheimer ezali:
1. Makambo oyo moto abotamaka na yango: Bato ya mayele bamoni ete ezali na ba gènes mosusu oyo esalaka ete moto akóma na maladi ya Alzheimer, mingimingi oyo babengi apolipoprotéine E (APOE).
2. Mbula: Likama ya kozwa maladi ya Alzheimer ebakisamaka na mbula, mpe bato mingi babɛlaka yango nsima ya mbula 65.
3. Maladi oyo moto moko ya libota na yo azali na yango: Soki moto moko ya libota na yo azali na maladi ya Alzheimer, yango ekoki kobakisela yo likama ya kozwa maladi yango.
4. Kozokisama na motó: Soki moto azokisamá na motó, mingimingi oyo ebungisaka ye makanisi, yango ekoki kobakisela ye maladi ya Alzheimer.
5. Maladi ya motema: Soki moto azali na maladi lokola tansiɔ, cholestérol, mpe diabɛti, akoki kokóma na maladi ya Alzheimer.
7. Kobimisa mɔ́tɔ: Kobimisa mɔ́tɔ ntango nyonso na bɔɔngɔ́ ekoki kopesa nzela na bokɔnɔ ya Alzheimer.
8. Kozanga bokatikati kati na biloko oyo bizali na kati ya nzoto (stress oxydatif): Kozanga bokatikati kati na biloko oyo bizali na kati ya nzoto (radicaux libres) mpe likoki ya nzoto ya kolongola yango na nzoto ekoki kopesa nzela na bokɔnɔ ya Alzheimer.
9. Bitando ya amyloïde mpe misisa ya bɔɔngɔ: Kotondana ya bitando ya amyloïde mpe misisa ya bɔɔngɔ na bɔɔngɔ ezali elembo ya maladi ya Alzheimer, kasi ntina oyo esalaka ete moto akóma na maladi yango eyebani mpenza te.
Ezali na ntina koyeba ete ntina ya maladi ya Alzheimer ezali makasi mpe mbala mosusu esangisi makambo wana nyonso.
Bolukiluki ezali kosalema mpo na koyeba malamu ndenge maladi yango esalaka mpe koyeba ndenge ya kosalisa yango malamu.
Vellas B, Andrieu S, Cantet C, Dartigues JF, Gauthier S: Long-term changes in ADAS-cog: what is clinically relevant for disease modifying trials in Alzheimer? J Nutr Health Aging. , 11 (4): 338-41.
Braak E, Griffing K, Arai K, Bohl J, Bratzke H, Braak H: Neuropathology of Alzheimer's disease: what is new since A. Alzheimer? Eur Arch Psychiatry Clin Neurosci. 1999, 249 Suppl 3 (): 14-22.
Kovacs GG: Can Creutzfeldt-Jakob disease unravel the mysteries of Alzheimer? Prion. 2016, 10 (5): 369-376.
Cankurtaran M, Yavuz BB, Cankurtaran ES, Halil M, Ulger Z, Ariogul S: Risk factors and type of dementia: vascular or Alzheimer? Arch Gerontol Geriatr. , 47 (1): 25-34.
Mahami-Oskouei M, Hamidi F, Talebi M, Farhoudi M, Taheraghdam AA, Kazemi T, Sadeghi-Bazargani H, Fallah E: Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer? Parasitol Res. 2016, 115 (8): 3169-74.
['Koboya: makambo ya monganga']
['Site oyo ezali kaka mpo na koteya mpe koyebisa bato makambo ya monganga, kasi ezali te mpo na kopesa toli to toli ya monganga.']
['Makambo oyo ezali na site yango esengeli te kosalelama mpo na koyeba maladi to kosalisa yango, mpe baoyo balingi kozwa toli ya monganga basengeli kotuna yango epai ya monganga oyo ayebi mosala yango malamu.']
['Tosengi na yo oyeba ete réseau neuronal oyo epesaka biyano na mituna, ezalaka mpenza malamu te soki ezali na makambo ya mituya. Na ndakisa, motango ya bato oyo bazali na maladi moko boye.']
['Sololá ntango nyonso na monganga to na moto mosusu oyo ayebi kosalisa maladi na yo. Koboya toli ya monganga te to kozela te mpo otángi likambo moko na site oyo. Soki okanisi ete ozali na maladi oyo esengeli kosalisa yo nokinoki, bengá 911 to kende na lopitalo ya pene. Site oyo to ndenge oyo ozali kosalela yango ezali na boyokani te na monganga ná moto oyo azali kosalisa yo.']
["Kozanga ndingisa: droit d'auteur"]
['Mobeko ya Copyright ya Milenere ya 1998, 17 U.S.C. § 512 (DMCA) epesi nzela na bakomi ya mikanda oyo bakanisi ete biloko oyo ezali na Internet ezali kobebisa lotomo na bango na kolanda mibeko ya copyright ya Etats-Unis. ']
['Soki ondimi na motema malamu ete makambo to biloko oyo ezali na site Internet to na ba service na biso ezali kobuka mibeko na yo, yo (to moto oyo azali na mokumba ya kobatela yo) okoki kotindela biso mokanda mpo na kosɛnga ete tólongola makambo to biloko yango to tópekisa yo kokɔta na yango. ']
['Basengeli kotinda bansango na mokanda na nzela ya email (tala na "Kotindelana" mpo na adresse ya email). ']
['Mibeko ya DMCA esengi ete mokanda na yo ya kofunda mbeba ya copyright ezala na makambo oyo elandi: (1) kolimbola mosala oyo ezali na droit ya copyright oyo bazali kofunda ete ebebisami; (2) kolimbola makambo oyo bazali kofunda ete ebebisi mpe makambo oyo ekoki mpo na kosalisa biso na koyeba esika makambo yango ezali; (3) makambo ya kosolola na yo, ata mpe adrɛsi na yo, nimero ya telefone mpe adrɛsi ya e-mail; (4) mokanda oyo okomi ete ondimi na motema malamu ete makambo oyo ozali kofunda ete ebebisami epesami nzela te na nkolo ya droit ya copyright, to na agent na ye, to na mibeko nyonso; ']
['(5) mokanda oyo okomi, oyo okotya sinyatili na yango mpo na komonisa ete makambo oyo okomaki ezali solo mpe ete ozali na lotomo ya kolandela lotomo ya babimisi oyo bazali koloba ete ebebisami; ']
['mpe (6) sinyatili ya moto oyo azali na lotomo ya kosala yango to ya moto oyo azali na lotomo ya kosala na nkombo na ye. ']
['Soki otye makambo nyonso te oyo ezali awa na likolo, yango ekoki kosala ete likambo na yo eumela.']
['Ndenge ya kosolola']
['Tosengi otindela biso email na motuna to likanisi nyonso.']
What causes alzheimer?
Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects the brain, causing memory loss, cognitive decline, and behavioral changes.
The exact cause of Alzheimer's disease is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors.
Some of the factors that may contribute to the development of Alzheimer's disease include:
1. Genetics: Certain genes have been identified that increase the risk of developing Alzheimer's disease, particularly the apolipoprotein E (APOE) gene.
2. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.
3. Family history: Having a family history of Alzheimer's disease may increase the risk of developing the condition.
4. Head injuries: A history of head injuries, particularly those that result in loss of consciousness, may increase the risk of Alzheimer's disease.
5. Cardiovascular risk factors: Conditions such as high blood pressure, high cholesterol, and diabetes may increase the risk of developing Alzheimer's disease.
6. Lifestyle factors: A sedentary lifestyle, poor diet, and lack of mental stimulation may increase the risk of Alzheimer's disease.
7. Inflammation: Chronic inflammation in the brain may contribute to the development of Alzheimer's disease.
8. Oxidative stress: An imbalance between the production of free radicals and the body's ability to detoxify them may contribute to the development of Alzheimer's disease.
9. Amyloid plaques and neurofibrillary tangles: The accumulation of amyloid plaques and neurofibrillary tangles in the brain is a hallmark of Alzheimer's disease, but the role they play in the development of the condition is not fully understood.
It is important to note that the cause of Alzheimer's disease is complex and likely involves a combination of these factors.
Research is ongoing to better understand the underlying mechanisms and develop effective treatments for this devastating condition.
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['Na ntina na']
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['Tobandi na mikanda ya minganga 35 millions ya PubMed/Medline. Lisusu, ba pages ya RefinedWeb.']
