Pathophysiologie ya cancer ya libumu ezali kolobela mbongwana ya mabe na misala ya physiologie mpe ba mécanismes oyo esalemaka na bokóli ya cancer ya libumu.
Ezali koyekola makambo ya bomoi mpe ya molekile oyo esalaka ete baselile ya kanser ekola mpe epalangana na ndenge ya mabe na kati ya libumu.
Yango ezali na ba facteur ya génétique, epigenetic, mpe ya milieu oyo esalaka ete cancer ya libɛlɛ ebanda, ekola, mpe ekende liboso.
Mwa mbongwana ya ntina ya pathophysiologique na cancer ya libɛlɛ ezali:
1. Mbongwana ya ba gène: Mbongwana ya ba gène mosusu, lokola BRCA1 mpe BRCA2, ekoki kobakisa likama ya kozwa kanser ya libɛlɛ.
Mbongwana wana ya nzoto ekoki kouta na makila to mpe moto akoki kozwa yango na bomoi na ye.
2. Kozanga bokatikati ya ba hormone: Ba hormone, mingimingi estrogène, ekoki kozala na ntina mingi mpo na bokóli ya kanser ya libɛlɛ.
Soki hormone ezali kosala malamu te to soki mwasi azali kozwa estrogène mingi, yango ekoki kobakisa likama ya kozwa kanser ya libɛlɛ.
3. Kobimisa mɔ́tɔ: Kobimisa mɔ́tɔ ntango molai na libɛlɛ ekoki kopesa nzela na bokɔnɔ ya kanser ya libɛlɛ na kopalanganisáká bokóli mpe kobika ya baselile ya kanser.
4. Etando oyo kanser ezali: Etando oyo ezali zingazinga ya kanser, na ndakisa baselile oyo ebundisaka maladi, mpe misisa ya makila, ekoki kosala ete kanser ya libɛlɛ ekola mpe epalangana.
5. Metastase: Kanser ya mabɛlɛ ekoki kopalangana na biteni mosusu ya nzoto na nzela ya misisa ya makila to ya makila, mpe yango ekoki kobimisa kanser mosusu na biteni mosusu ya nzoto.
Koyeba ndenge maladi ya kanser ya libɛlɛ ezalaka ezali na ntina mingi mpo na koyeba ndenge ya komibatela, koyeba yango noki, mpe kosalisa yango.
Underwood SM: Breast cancer in African American women: nursing essentials. ABNF J. , 17 (1): 3-14.
Paliwal SR, Paliwal R, Agrawal GP, Vyas SP: Liposomal nanomedicine for breast cancer therapy. Nanomedicine (Lond). 2011, 6 (6): 1085-100.
Rauch GM, Adrada BE: Comparison of Breast MR Imaging with Molecular Breast Imaging in Breast Cancer Screening, Diagnosis, Staging, and Treatment Response Evaluation. Magn Reson Imaging Clin N Am. 2018, 26 (2): 273-280.
Wei H, Wang H, Ji Q, Sun J, Tao L, Zhou X: NRBP1 is downregulated in breast cancer and NRBP1 overexpression inhibits cancer cell proliferation through Wnt/β-catenin signaling pathway. Onco Targets Ther. 2015, 8 (): 3721-30.
Eden JA: Human breast cancer stem cells and sex hormones--a narrative review. Menopause. 2010, 17 (4): 801-10.
Schneider BP, Winer EP, Foulkes WD, Garber J, Perou CM, Richardson A, Sledge GW, Carey LA: Triple-negative breast cancer: risk factors to potential targets. Clin Cancer Res. 2008, 14 (24): 8010-8.
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What is pathophysiology of breast cancer?
Pathophysiology of breast cancer refers to the abnormal changes in the normal physiological processes and mechanisms that occur in the development and progression of breast cancer.
It involves the study of the underlying biological and molecular mechanisms that lead to the uncontrolled growth and spread of cancer cells in the breast tissue.
This includes the genetic, epigenetic, and environmental factors that contribute to the initiation, promotion, and progression of breast cancer.
Some of the key pathophysiological changes in breast cancer include:
1. Genetic mutations: Mutations in certain genes, such as BRCA1 and BRCA2, can increase the risk of developing breast cancer.
These mutations can be inherited or acquired during a person's lifetime.
2. Hormonal imbalances: Hormones, particularly estrogen, can play a role in the development and growth of breast cancer.
An imbalance in hormone levels or exposure to excess estrogen can increase the risk of breast cancer.
3. Inflammation: Chronic inflammation in the breast tissue can contribute to the development of breast cancer by promoting the growth and survival of cancer cells.
4. Tumor microenvironment: The environment surrounding the tumor, including the extracellular matrix, immune cells, and blood vessels, can influence the growth and spread of breast cancer.
5. Metastasis: Breast cancer can spread to other parts of the body through the lymphatic system or bloodstream, leading to the formation of secondary tumors in distant organs.
Understanding the pathophysiology of breast cancer is crucial for developing effective prevention, early detection, and treatment strategies.
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