Alzheimer natna chu neurodegenerative natna a ni a, thluak a nghawng ber a, hriatna a hloh a, thil hriatna a tlahniam a, nungchang pawh a danglam ṭhîn.
Alzheimer natna lo chhuah chhan chiah chu hriat chian a ni lo va; mahse, chi inthlah chhâwn te, hmun leh tui inhnaih te, leh nunphungte chuan a thlen nia rin a ni.
Alzheimer natna awmtîrtu thil ṭhenkhatte chu:
1. Thlahtute: Alzheimer natna vei theihna tûr gene ṭhenkhat, a bîk takin apolipoprotein E (APOE) gene chu hmuh chhuah a ni a.
2. Kum: Kum a lo upat chhoh zêl chuan Alzheimer natna vei theihna chu a pung a, mi tam zâwk chu kum 65 an tlin hnuah an vei ṭan ṭhîn.
3. Chhûngkaw chanchin: Chhûngkaw zîngah Alzheimer natna vei an awm chuan, chu natna vei theihna chu a pung thei a ni.
4. Lu hliam: Lu hliam, a bîk takin hriatna bo phahna hliam tawh chuan Alzheimer natna a thlen theihzia a tizual thei a.
5. Lung leh thisen lama harsatna: Thisen sâng, cholesterol sâng, leh diabetes te chuan Alzheimer natna vei theihna a tizual thei a.
6. Nun dân: Inkhung rengna te, chaw ṭha lo ei te, leh rilru thawh rimna tlêmna te chuan Alzheimer natna vei theihna a tizual thei a.
7. Pânna: Thluaka pânna awm reng chuan Alzheimer natna a thlen thei a.
8. Oxidative stress: Free radical siam chhuahna leh taksain a tih thianghlim theihna inkâra inbûk tâwk lohna chuan Alzheimer natna a thlen thei a.
9. Amyloid plaque leh neurofibrillary tangles: Thluaka amyloid plaque leh neurofibrillary tangles pung khâwm chu Alzheimer natna chhinchhiahna a ni a; mahse, chu natna lo awm tûra an thawh dân chu hriat chian a la ni lo.
Alzheimer natna lo chhuah chhan chu a khirh hle a, hêng thilte hi a inkawp a nih a rinawm tih hriat a pawimawh hle.
He natna hlauhawm tak enkawlna ṭha leh a chhan hriat thiam nân zirna chu kalpui zêl a ni a.
Vellas B, Andrieu S, Cantet C, Dartigues JF, Gauthier S: Long-term changes in ADAS-cog: what is clinically relevant for disease modifying trials in Alzheimer? J Nutr Health Aging. , 11 (4): 338-41.
Braak E, Griffing K, Arai K, Bohl J, Bratzke H, Braak H: Neuropathology of Alzheimer's disease: what is new since A. Alzheimer? Eur Arch Psychiatry Clin Neurosci. 1999, 249 Suppl 3 (): 14-22.
Kovacs GG: Can Creutzfeldt-Jakob disease unravel the mysteries of Alzheimer? Prion. 2016, 10 (5): 369-376.
Cankurtaran M, Yavuz BB, Cankurtaran ES, Halil M, Ulger Z, Ariogul S: Risk factors and type of dementia: vascular or Alzheimer? Arch Gerontol Geriatr. , 47 (1): 25-34.
Mahami-Oskouei M, Hamidi F, Talebi M, Farhoudi M, Taheraghdam AA, Kazemi T, Sadeghi-Bazargani H, Fallah E: Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer? Parasitol Res. 2016, 115 (8): 3169-74.
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['(5) Thu dik lo sawi hlauvin i hming ziakna, hriattîrna thute chu a dikzia leh i bawhchhiat nia sawi dikna chanvo humhim tûra thuneihna i nei tih i puan chhuahna;']
['Tin, (6) copyright neitu emaw, a aiawha thil ti tûra thuneihna neitu emaw kutziak emaw, electronic signature emaw a ni tûr a ni.']
['A chunga mi ang hian i thil dilna chu a chhan theih a ni.']
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What causes alzheimer?
Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects the brain, causing memory loss, cognitive decline, and behavioral changes.
The exact cause of Alzheimer's disease is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors.
Some of the factors that may contribute to the development of Alzheimer's disease include:
1. Genetics: Certain genes have been identified that increase the risk of developing Alzheimer's disease, particularly the apolipoprotein E (APOE) gene.
2. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.
3. Family history: Having a family history of Alzheimer's disease may increase the risk of developing the condition.
4. Head injuries: A history of head injuries, particularly those that result in loss of consciousness, may increase the risk of Alzheimer's disease.
5. Cardiovascular risk factors: Conditions such as high blood pressure, high cholesterol, and diabetes may increase the risk of developing Alzheimer's disease.
6. Lifestyle factors: A sedentary lifestyle, poor diet, and lack of mental stimulation may increase the risk of Alzheimer's disease.
7. Inflammation: Chronic inflammation in the brain may contribute to the development of Alzheimer's disease.
8. Oxidative stress: An imbalance between the production of free radicals and the body's ability to detoxify them may contribute to the development of Alzheimer's disease.
9. Amyloid plaques and neurofibrillary tangles: The accumulation of amyloid plaques and neurofibrillary tangles in the brain is a hallmark of Alzheimer's disease, but the role they play in the development of the condition is not fully understood.
It is important to note that the cause of Alzheimer's disease is complex and likely involves a combination of these factors.
Research is ongoing to better understand the underlying mechanisms and develop effective treatments for this devastating condition.
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