Diabetes natna awm dân leh a natna inkaichhawn dân chu eng nge ni?
Diabetes natna zirna (pathophysiology of diabetes) chu natna lo awm chhante zirna a ni.
Diabetes mellitus hi taksa pumpui natna chi khat a ni a, chu chu insulin secretion emaw, insulin action emaw, a pahniha a tihsual avânga thisena sugar (glucose) a tam vâng a ni.
Diabetes natna awm dân leh natna inkaichhawn dân chu natna lo awm dân thlentu genetic, environmental, leh nunphungte inzawmkhâwmna a ni.
Type 1 diabetes-ah chuan, autoimmune natnain insulin siamtu beta cells-te a tichhia a, chu chuan insulin siam chhuahna a tiṭha lo ṭhîn.
Chu chuan thisena glucose awm dân a siam ṭha thei lo va, hyperglycemia (thisen-a sugar a tam) a thlen a ni.
Type 2 diabetes-ah chuan, a natna awm dân chu a khirh zâwk a, insulin resistance leh insulin secretion tihhniam a tel ve ve a ni.
Insulin resistance chu taksa chhûnga cell-te'n insulin an dawn ṭhat loh avângin a lo awm a, chu chuan glucose chu chakna atâna ṭha taka an hmang thei lo va.
Chu chuan insulin resistance hneh tumin pancreas chu insulin a siam tam zâwk a, mahse, a hnuah chuan a mamawh zat a siam chhuak thei tawh lo va, insulin siam chhuahna chu a tlahniam ta a ni.
Naupai laia natna chi khat, gestational diabetes chu hormone inthlâk danglamna avângin a awm a, chu chuan insulin resistance a thlen a ni.
Chu chuan thisena glucose a tihpun phah a ni.
Diabetes natna hian natna dang a thlen belh a, thisen zung te, thluak te, leh taksa pêngte a tichhia a, chu chuan natna khirh tak tak, lung natna te, thluak lam natna te, kal natna te, leh mitdelna te a thlen thei a ni.
He natna benvawn tak enkawlna leh invenna ṭha tak siam chhuah nân chuan natna hrik pai natna (diabetes) hriat thiam a pawimawh hle.
Biochemistry and pathophysiology of diabetes. Proceedings of conference on pathophysiology and treatment of diabetes mellitus. 1990. Mol Cell Biochem. 1992, 109 (2): 97-204.
Surampudi PN, John-Kalarickal J, Fonseca VA: Emerging concepts in the pathophysiology of type 2 diabetes mellitus. Mt Sinai J Med. 2009, 76 (3): 216-26.
Johnson D: Selected pathophysiology of diabetes. Semin Perioper Nurs. 1998, 7 (3): 164-78.
Hirsch IB: The changing faces of diabetes. Prim Care. 2003, 30 (3): 499-510.
Guthrie RA, Guthrie DW: Pathophysiology of diabetes mellitus. Crit Care Nurs Q. , 27 (2): 113-25.
Felig P: Pathophysiology of diabetes mellitus. Med Clin North Am. 1971, 55 (4): 821-34.
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What is pathophysiology of diabetes?
Pathophysiology of diabetes refers to the study of the disordered physiological processes that lead to the development of diabetes mellitus.
Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels that result from defects in insulin secretion, insulin action, or both.
The pathophysiology of diabetes involves the complex interplay of genetic, environmental, and lifestyle factors that contribute to the development of the disease.
In type 1 diabetes, the pathophysiology involves an autoimmune destruction of the insulin-producing beta cells in the pancreas, leading to a deficiency in insulin production.
This results in an inability to regulate blood glucose levels, leading to hyperglycemia (high blood sugar).
In type 2 diabetes, the pathophysiology is more complex and involves both insulin resistance and impaired insulin secretion.
Insulin resistance occurs when the body's cells do not respond properly to insulin, leading to an inability to effectively use glucose for energy.
This causes the pancreas to produce more insulin to try to overcome the resistance, but over time, the pancreas may not be able to keep up with the demand, leading to a decrease in insulin production.
Gestational diabetes, which occurs during pregnancy, is caused by hormonal changes that lead to insulin resistance.
The placenta produces hormones that can block the action of insulin, leading to an increase in blood glucose levels.
The pathophysiology of diabetes also involves the development of complications, such as damage to blood vessels, nerves, and organs, which can lead to serious health problems like heart disease, stroke, kidney disease, and vision loss.
Understanding the pathophysiology of diabetes is crucial for developing effective treatments and prevention strategies for this chronic disease.
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