How to treat Prostate cancer?

['Kelg-y seb-kãngã']

Wãn to la b tõe n tɩp kãnsɛɛrã?

Bãas nins sẽn tõe n kʋ nedã yaa wʋsgo. Bãas kẽer la b boond tɩ "prostatite".

B tɩpda bãas kẽer woto:

1. Bãagã gesg sõma: Bãagã gesg sõma baoodame tɩ b ges bãagã sõma n ges a sã n pa tar sãoore, la b maan vaeesg wakat fãa.

A tõe n yɩɩ sõma ne rap nins sẽn tar kãnsɛɛr sẽn pa tar yell wʋsgã.

2. Wopere: B sã n yãk pʋg-yoodrã, yaa woperasɩõ n yãkd pʋg-yoodrã.

B tõe n maana woperasɩõ sẽn yaa vẽenega, bɩ b tõe n maana woperasɩõ sẽn yaa fĩ-fĩi ne te-bɛd n ges bãadã.

3. Vẽenem tɩbsg: B tɩpda kãnsɛɛrã ne vẽenem sẽn tar pãng wʋsg sẽn na yɩl n kʋ a selill dãmbã.

B tõe n ning-a-la we-n-vɩʋʋgã pʋgẽ (masĩn sẽn be yĩngẽ wã) bɩ we-vɩʋʋgã pʋgẽ (b sẽn ningd bũmb sẽn pẽ ne weoogã).

4. Hormoon tɩbsg: B tɩbsgã boogda rao wã yĩngã kõb-bogd (androgènes) sẽn be yĩngã pʋgẽ wã, tɩ rẽ tõe n boog bɩ kɩt tɩ kãnsɛɛrã ra le bɩt tao-tao ye.

B tõe n dɩka- a lame n tɩp a meng bɩ n naag ne tɩbsg a taab n tɩp- a.

5. Bãas tɩbsg ne tɩt buud toor-toore: Bãas tɩbsg kãngã tũnugda ne tɩt n kʋ kãnsɛɛrã selill dãmba.

B tõe n dɩka- a lame n tɩp kãnsɛɛr sẽn kẽng taoor sẽn sãeeg yĩngẽ wã.

6. Bãasã tɩbsgo: B tɩbsgã sõngda yĩngã pãn-tõog sẽn na yɩl t'a zab ne kãnsɛɛrã.

B tõe n dɩka- a lame n tɩp kãnsɛɛr sẽn kẽng taoor sẽn pa sak tɩbsg a taab ye.

7. Bãas kẽer tɩbsg: Bãas kẽer tɩbsg baooda bõn-buud wall poroteẽ rãmb sẽn sõngd kãnsɛɛrã selilɛɛr dãmb tɩ b bɩt la b ket n vɩ.

B tõe n dɩka- a lame n tɩp kãnsɛɛr sẽn kẽng taoor sẽn pa sak tɩbsg a taab ye.

8. Logtor sẽn maand ne waoodã: Logtor sẽn maand woto wã tũnugda ne waood sẽn yaa toog wʋsg n kɩt tɩ kãnsɛɛrã selill dãmb kiidẽ.

B tõe n dɩka- a lame n tɩp kãnsɛɛr sẽn sɩng bɩ a sẽn lebg n wa tɩbsg a taab poor yĩnga.

9. Vẽenem sẽn tar pãng wʋsg (HIFU): Vẽenem kãngã tũnugda ne bʋrg sẽn tar pãng wʋsg n wulumd kãnsɛɛrã selill dãmb n sãamdẽ.

B tõe n dɩka- a lame n tɩp kãnsɛɛr sẽn sɩng bɩ a sẽn lebg n wa tɩbsg a taab poor yĩnga.

10. Gũusg sõma: Manesem kãngã baoodame tɩ b ges kãnsɛɛrã yell sõma n ges a sã n pa tar bãaga, la b pa segd n sɩng tɩbsg tɩ bãagã pa wa bɩ tɩ pa toeem ye.

A tõe n yɩɩ sõma ne rap nins sẽn kʋʋlã, b sã n tara kãnsɛɛr sẽn bɩt bilf-bilf ne bãas a taab sẽn yaa kãn-kãe.

Tara yõod tɩ y sõs ne logtoɛɛmbã n bãng tɩbsg buud fãa sẽn tõe n yɩ sõma n yɩɩda.

['Sõss sẽn tik Biiblã zugu']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.

Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.

Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.

Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.

Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.

de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.

Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.

['Bãngr-gomde: logtoeemdã']

['Yaa zãmsg la kibay kũun yĩng bal la b yiisd sit kãngã, la pa logtoeemdã wɛɛngẽ sagls bɩ tʋʋm-sõng maaneg yĩng ye.']

['B pa segd n tũnug ne kɩbay nins b sẽn kõ wã n bao bãag bɩ zu-loɛɛg tɩɩm ye. Sẽn dat-b tɩbsg b toor segd n tɩ yãa logtor sẽn tar sor n tõe n tɩp-ba.']

['D tẽeg tɩ b sẽn maand to-to n leokd sogsgã to-to wã pa zems ye.']

['Y sã n wa karemd bũmb sẽn be sɩtã pʋgẽ, bɩ y ra tol n yĩm tɩ y segd n tɩ gesa logtor ye. Y sã n tagsdẽ tɩ y tara yĩn-wɩsgr yell bɩ y bool 911 wall y kẽng logtor yirã.']

['Bas-m-yam: sɛbã zãab wɛɛngẽ']

['Digital Millennium Copyright Act sẽn yaa yʋʋmd 1998 soabã, 17 U.S.C. § 512 (DMCA) kõta sor tɩ ned sã n tẽed tɩ bũmb sẽn be ẽntɛrnetã pʋgẽ kɩɩsda a sẽn tar sor n tõe n maan bũmb ninsã, a tõe n tɩ kos n paam n lebse.']

['Yãmb sã n tẽed ne pʋ-peelem tɩ bũmb sẽn be tõnd sɩt wɛɛbã pʋgẽ bɩ tõnd tʋʋm-noyã pʋsẽ n sãamd yãmb dʋrwa wã, yãmb (bɩ y tʋʋm-tʋmdã) tõe n toola tõnd koɛɛg n kos tɩ d yiis bũmbã wall d gɩdg tɩ y ra paam n kẽ ye.']

['B segd n tʋma koees ne ẽtɛrnetã (Ges-y ẽtɛrnetã adɛrs sẽn be babg ning sẽn yet tɩ "Tõnd sõsg zĩigã").']

['DMCA wã baoodame tɩ yãmb sẽn na n togs ned tɩ b maan-a-la bũmb sẽn kɩɩsd a sẽn tar sor n tõe n maan bũmb ningã, bɩ y wilg-a bũmb nins sẽn pʋgdã: 1) bũmb ning sẽn kɩt tɩ b maan-a bũmb ningã, 2) bũmb ning sẽn kɩt tɩ b maan-a bũmb ningã, la y wilg-d bũmb ning sẽn kɩt tɩ d tõe n bãng a sẽn be zĩig ninga. 3) y sẽn tõe n paam ned n gom ne-a to-to, n paas y adɛrsã, telefõnnã nimero, la y e-mailã. 4) y sã n yeel tɩ y kɩsa sɩd tɩ bũmb ning sẽn kɩt tɩ y maan bũmb ningã pa ned ning sẽn tar sor n tõe n maan bũmbã, bɩ a tʋm-tʋmdã, bɩ laloa wã sẽn kõ sor tɩ y maan ye.']

['5) Y sã n wa rat n wilg tɩ y pa tar sor n na n kɩɩs ned a to, bɩ y gʋls sebr n wilg tɩ y sẽn togsã yaa sɩda, la tɩ y tara sor n na n wilg tɩ nedã sẽn maan bũmb ning n kɩɩs yãmb dʋrwa rãmbã yaa sɩda.']

['La (6) sɛb nins sẽn tar-b sor n na n yiis sɛbã, bɩ ned sẽn tar sor n na n tʋm sɛbã yiisg yĩngã.']

['Y sã n pa gʋls kibay nins sẽn be yĩngrã, tõe n kɩtame tɩ y yẽgengã kaoos n pa sa ye.']

['Sõsg ne neda']

['Y sã n tar sokr bɩ y sẽn dat n bãnge, bɩ y gʋls-d lɛtr n tool-do.']

How to treat prostate cancer?

There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.

Some common treatments include:

1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.

It may be suitable for men with low-risk prostate cancer.

2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.

It can be done through open surgery or laparoscopically (using small incisions and specialized tools).

3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.

It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).

4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.

It can be used alone or in combination with other treatments.

5. Chemotherapy: This treatment uses drugs to kill cancer cells.

It may be used for advanced prostate cancer that has spread to other parts of the body.

6. Immunotherapy: This treatment helps the immune system fight cancer.

It may be used for advanced prostate cancer that has not responded to other treatments.

7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.

It may be used for advanced prostate cancer that has not responded to other treatments.

8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.

It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.

It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.

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