Bãngr ning sẽn boond tɩ " cancer de la prostate " wã sẽn yaa bãag ning sẽn wat ne bãas ninsã, la a sẽn wat ne yɛl ninsã wilgda bũmb ning sẽn kɩt tɩ bãagã wat ne bãas ninsã.
Kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd yaa kãnsɛɛr sẽn tar pãng n yɩɩd
Yaa raoã yĩngẽ wã la raoã rog-bõonegã be.
B pa mi bũmb ning sẽn sɩd wat ne kãnsɛɛrã zãng ye.
Wala makre, bãagã sẽn tar ned ningã, a zakã neb sẽn zoe n tar bãagã, a buudã, la a rogmã sẽn toeem to-to wã.
Sẽn paase, rap nins sẽn tar kamb sẽn bẽed kãnsɛɛrã tõe n wa paama bã-kãnga.
Yaa bãag sẽn tõe n wa ne bãas a taab sẽn yɩɩd bãas a taabã.
Woto tõe n yɩɩ bãag sẽn wat ne bãas a taab sẽn tõe n wa ne bãas a taaba.
Zĩn-kãensã tõe n kɩtame tɩ selill dãmbã bɩt tɩ pa tũ ne b sẽn datã, tɩ wa baas ne kãnsɛɛre.
Bãagã sã n wa bɩtẽ, a tõe n kẽe yĩngã wil la a wil a taab sẽn pẽ-a, wala makre, pʋgã, pʋg-sadgã, la zɩ-biis nins sẽn pẽ-a wã.
Wakat ninga, kãnsɛɛrã tõe n yiime n tɩ kẽ yĩngã zĩis a taaba, n tũ ne zɩɩmã bɩ zɩ-pellã n tɩ sãeege.
Bãagã sã n wa piuugi, a tɩbsgã tõe n yɩɩ toogo.
Sẽn yɩɩd fãa, yaa rao ne pag sẽn kẽed ne raoolmã bɩ poglmã n wat ne kãnsɛɛrã.
Woto kɩtame tɩ b pa le tar tɩɩm sẽn tõe n sõng-b tɩ b tõog n mao ne bãagã ye.
Sẽn na n baase, porositã kãnsɛɛrã bãag kɩtdame tɩ selill dãmbã bɩt n pa tar pãng n welgd b mens porositã pʋgẽ, tɩ rẽ tõe n tũ ne rog-n-mikã, hormoon dãmbã la yɛl a taab sẽn be zĩigã.
Bãng bãaga sẽn wat ne bũmb ninga yaa tɩlae sẽn na yɩl n tõog n maan tɩbsgo, la sẽn na yɩl tɩ bãad-rãmb nins sẽn bẽed kãnsɛɛrã paam laafɩ.
Zobniw CM, Causebrook A, Fong MK: Clinical use of abiraterone in the treatment of metastatic castration-resistant prostate cancer. Res Rep Urol. 2014, 6 (): 97-105.
Lim HY, Agarwal AM, Agarwal N, Ward JH: Recurrent epistaxis as a presenting sign of androgen-sensitive metastatic prostate cancer. Singapore Med J. 2009, 50 (5): e178-80.
Kohli M, Qin R, Jimenez R, Dehm SM: Biomarker-based targeting of the androgen-androgen receptor axis in advanced prostate cancer. Adv Urol. 2012, 2012 (): 781459.
Nelson JB, Hedican SP, George DJ, Reddi AH, Piantadosi S, Eisenberger MA, Simons JW: Identification of endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate. Nat Med. 1995, 1 (9): 944-9.
Msaouel P, Nandikolla G, Pneumaticos SG, Koutsilieris M: Bone microenvironment-targeted manipulations for the treatment of osteoblastic metastasis in castration-resistant prostate cancer. Expert Opin Investig Drugs. 2013, 22 (11): 1385-400.
Kotani K, Sekine Y, Ishikawa S, Ikpot IZ, Suzuki K, Remaley AT: High-density lipoprotein and prostate cancer: an overview. J Epidemiol. 2013, 23 (5): 313-9.
Jadvar H: Molecular imaging of prostate cancer: a concise synopsis. Mol Imaging. , 8 (2): 56-64.
['Bãngr-gomde: logtoeemdã']
['Yaa zãmsg la kibay kũun yĩng bal la b yiisd sit kãngã, la pa logtoeemdã wɛɛngẽ sagls bɩ tʋʋm-sõng maaneg yĩng ye.']
['B pa segd n tũnug ne kɩbay nins b sẽn kõ wã n bao bãag bɩ zu-loɛɛg tɩɩm ye. Sẽn dat-b tɩbsg b toor segd n tɩ yãa logtor sẽn tar sor n tõe n tɩp-ba.']
['D tẽeg tɩ b sẽn maand to-to n leokd sogsgã to-to wã pa zems ye.']
['Y sã n wa karemd bũmb sẽn be sɩtã pʋgẽ, bɩ y ra tol n yĩm tɩ y segd n tɩ gesa logtor ye. Y sã n tagsdẽ tɩ y tara yĩn-wɩsgr yell bɩ y bool 911 wall y kẽng logtor yirã.']
['Bas-m-yam: sɛbã zãab wɛɛngẽ']
['Digital Millennium Copyright Act sẽn yaa yʋʋmd 1998 soabã, 17 U.S.C. § 512 (DMCA) kõta sor tɩ ned sã n tẽed tɩ bũmb sẽn be ẽntɛrnetã pʋgẽ kɩɩsda a sẽn tar sor n tõe n maan bũmb ninsã, a tõe n tɩ kos n paam n lebse.']
['Yãmb sã n tẽed ne pʋ-peelem tɩ bũmb sẽn be tõnd sɩt wɛɛbã pʋgẽ bɩ tõnd tʋʋm-noyã pʋsẽ n sãamd yãmb dʋrwa wã, yãmb (bɩ y tʋʋm-tʋmdã) tõe n toola tõnd koɛɛg n kos tɩ d yiis bũmbã wall d gɩdg tɩ y ra paam n kẽ ye.']
['B segd n tʋma koees ne ẽtɛrnetã (Ges-y ẽtɛrnetã adɛrs sẽn be babg ning sẽn yet tɩ "Tõnd sõsg zĩigã").']
['DMCA wã baoodame tɩ yãmb sẽn na n togs ned tɩ b maan-a-la bũmb sẽn kɩɩsd a sẽn tar sor n tõe n maan bũmb ningã, bɩ y wilg-a bũmb nins sẽn pʋgdã: 1) bũmb ning sẽn kɩt tɩ b maan-a bũmb ningã, 2) bũmb ning sẽn kɩt tɩ b maan-a bũmb ningã, la y wilg-d bũmb ning sẽn kɩt tɩ d tõe n bãng a sẽn be zĩig ninga. 3) y sẽn tõe n paam ned n gom ne-a to-to, n paas y adɛrsã, telefõnnã nimero, la y e-mailã. 4) y sã n yeel tɩ y kɩsa sɩd tɩ bũmb ning sẽn kɩt tɩ y maan bũmb ningã pa ned ning sẽn tar sor n tõe n maan bũmbã, bɩ a tʋm-tʋmdã, bɩ laloa wã sẽn kõ sor tɩ y maan ye.']
['5) Y sã n wa rat n wilg tɩ y pa tar sor n na n kɩɩs ned a to, bɩ y gʋls sebr n wilg tɩ y sẽn togsã yaa sɩda, la tɩ y tara sor n na n wilg tɩ nedã sẽn maan bũmb ning n kɩɩs yãmb dʋrwa rãmbã yaa sɩda.']
['La (6) sɛb nins sẽn tar-b sor n na n yiis sɛbã, bɩ ned sẽn tar sor n na n tʋm sɛbã yiisg yĩngã.']
['Y sã n pa gʋls kibay nins sẽn be yĩngrã, tõe n kɩtame tɩ y yẽgengã kaoos n pa sa ye.']
['Sõsg ne neda']
['Y sã n tar sokr bɩ y sẽn dat n bãnge, bɩ y gʋls-d lɛtr n tool-do.']
What is pathophysiology of prostate cancer?
The pathophysiology of prostate cancer refers to the underlying mechanisms and processes that lead to the development and progression of the disease.
Prostate cancer is a malignant tumor that arises from the cells of the prostate gland, which is a small, walnut-shaped organ located below the bladder in men.
The prostate gland produces seminal fluid, which nourishes and transports sperm.
The exact cause of prostate cancer is not fully understood, but several factors are known to increase the risk of developing the disease.
These include age, family history, race, and certain genetic mutations.
Prostate cancer is more common in older men, with the majority of cases occurring in men over the age of 65.
Additionally, men with a family history of prostate cancer are at an increased risk, as are African American men and men of Caribbean descent.
The pathophysiology of prostate cancer involves the uncontrolled growth and division of cells within the prostate gland.
This can occur due to genetic mutations that lead to the overexpression of certain growth factors or the inactivation of tumor suppressor genes.
These mutations can result in the unregulated growth of cells, leading to the formation of a tumor.
As the tumor grows, it can invade nearby tissues and organs, such as the bladder, rectum, and nearby lymph nodes.
In some cases, cancer cells can break away from the primary tumor and spread to other parts of the body through the bloodstream or lymphatic system, a process known as metastasis.
Once the cancer has spread, it can be more difficult to treat.
Prostate cancer can also be influenced by hormonal factors, particularly the androgen hormone testosterone.
Testosterone can stimulate the growth of prostate cancer cells, and many treatments for prostate cancer aim to reduce the levels of this hormone or block its effects.
In summary, the pathophysiology of prostate cancer involves the uncontrolled growth and division of cells within the prostate gland, which can be influenced by genetic, hormonal, and environmental factors.
Understanding the underlying mechanisms of the disease is crucial for developing effective treatments and improving outcomes for patients with prostate cancer.
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['D sɩngda ne sɛb milyõ 35 sẽn tik Biiblã zug n yiisd tɩbsg wɛɛngẽ.']
