What is prognosis of Alzheimer?

['Whakarongo ki tēnei whārangi']

He aha te tohu o te mate a Alzheimer?

He kino te matapae o te mate a Alzheimer, i te mea he mate whakamua, he mate whakaheke hoki, kaore he rongoa e mohiotia ana.

He rerekē te tere o te haere o te mate i te tangata ki te tangata, engari ka kino haere te mate i te roanga o te wā, ka heke haere ngā āheinga ā-hinengaro me te tinana.

I te haere o te mate, ka raru pea te tangata i te wareware, te uaua ki te reo me te whakawhitiwhiti korero, te pohehe, me nga rereketanga o te wairua me te whanonga.

Ka mutu, ka kore pea e taea e rātau te tiaki i a rātau anō, ā, ka hiahiatia he āwhina wā-katoa.

Ko te toharite o te oranga o te mate i muri i te kitenga ko te 8-10 tau, engari ka rereke tenei i runga i te pakeke o te tangata, te hauora katoa, me etahi atu mea.

Ahakoa kaore he rongoa, ka taea e nga maimoatanga me nga maimoatanga te awhina i nga tohu me te whakapai ake i te kounga o te ora mo te hunga e mate ana i te mate a Alzheimer.

['Ngā tohutoro']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Kaldjian LC: Survival versus prognosis in Alzheimer disease. Ann Intern Med. 2004, 141 (7): 575; author reply 575.

Mayeux R, Stern Y, Sano M: Heterogeneity and prognosis in dementia of the Alzheimer type. Bull Clin Neurosci. 1985, 50 (): 7-10.

DeKosky ST, Golde T: Cerebrospinal Biomarkers in Alzheimer Disease-Potential Roles as Markers of Prognosis and Neuroplasticity. JAMA Neurol. 2016, 73 (5): 508-10.

Yaffe K: Treatment of Alzheimer disease and prognosis of dementia: time to translate research to results. JAMA. 2010, 304 (17): 1952-3.

Zhu B, Chen X, Li W, Zhou D: Effect of Alzheimer Disease on Prognosis of Intensive Care Unit (ICU) Patients: A Propensity Score Matching Analysis. Med Sci Monit. 2022, 28 (): e935397.

Malpetti M, Joie R, Rabinovici GD: Tau Beats Amyloid in Predicting Brain Atrophy in Alzheimer Disease: Implications for Prognosis and Clinical Trials. J Nucl Med. 2022, 63 (6): 830-832.

Schaeffer EL, Figueiro M, Gattaz WF: Insights into Alzheimer disease pathogenesis from studies in transgenic animal models. Clinics (Sao Paulo). 2011, 66 Suppl 1 (): 45-54.

Bhagwat N, Pipitone J, Voineskos AN, Chakravarty MM: An artificial neural network model for clinical score prediction in Alzheimer disease using structural neuroimaging measures J Psychiatry Neurosci. 2019, 44 (4): 246-260.

Vermunt L, van Paasen AJL, Teunissen CE, Scheltens P, Visser PJ, Tijms BM: Alzheimer disease biomarkers may aid in the prognosis of MCI cases initially reverted to normal. Neurology. 2019, 92 (23): e2699-e2705.

Raji MA, Brady SR: Mirtazapine for treatment of depression and comorbidities in Alzheimer disease. Ann Pharmacother. 2001, 35 (9): 1024-7.

['Whakakahoretanga: hauora']

['Ko tenei paetukutuku e whakaratohia ana mo nga kaupapa ako me nga korero anake, kaore hoki e whakarato i nga tohutohu hauora, i nga ratonga ngaio ranei.']

['Kaua e whakamahia ngā mōhiohio e whakaratohia ana hei tātaritanga, hei whakaora rānei i tētahi raruraru hauora, mate rānei, ā, ko te hunga e rapu ana i te tohutohu hauora whaiaro me kōrero ki tētahi tākuta whai raihana.']

['Kia mōhio mai koe ko te whatunga pūtau e whakaputa ana i ngā whakautu ki ngā pātai, he tino hē ina tae mai ki te ihirangi tau. Hei tauira, ko te tokomaha o ngā tāngata kua tohua he mate tauwhāiti.']

['Me rapu tonu i te tohutohu a tō tākuta, i tētahi atu kaiwhakarato hauora whai tohu rānei e pā ana ki tētahi mate hauora. Kaua rawa e whakahawea ki te tohutohu hauora ngaio, te whakaroa rānei ki te rapu i te mea nā tētahi mea i pānuihia e koe i tēnei paetukutuku. Ki te whakaaro koe he mate hauora ohorere pea koe, waea atu ki te 911 ka haere ki te rūma ohorere tata tonu. Kāore he hononga tākuta-tūroro i hangaia e tēnei paetukutuku, i tōna whakamahinga rānei. Kāore a BioMedLib, ōna kaimahi rānei, tētahi kaitohutohu rānei ki tēnei paetukutuku, e whakaatu ana, e tohu ana rānei, e pā ana ki ngā mōhiohio e whakaratohia ana i konei, ki tōna whakamahinga rānei.']

['Whakakahoretanga: mana pupuri']

['Ko te Ture Mana pupuri Mamati Mamati o te tau 1998, 17 U.S.C. § 512 (te DMCA) e whakarato ana i te whakahoki mo nga rangatira mana pupuri e whakapono ana ko nga rauemi e puta ana i runga i te Ipurangi e takahi ana i o raatau mana i raro i te ture mana pupuri a US. ']

['Mēnā e whakapono pono ana koe e takahi ana tētahi ihirangi, rauemi rānei e wātea ana i runga i tō mātou paetukutuku, ratonga rānei i tō mana pupuri, ka taea e koe (tō māngai rānei) te tuku pānui ki a mātou e tono ana kia tangohia te ihirangi, rauemi rānei, kia āraia rānei te uru atu ki a ia. ']

["Me tuku ngā whakamōhiotanga ā-tuhi mā te īmēra (tirohia te wāhanga 'Whakapā' mō te wāhitau īmēra). "]

['E hiahiatia ana e te DMCA kia whakaurua ki tō whakamōhiotanga mō te whakawātea mana pupuri i ngā mōhiohio e whai ake nei: (1) whakaahuatanga o te mahi mana pupuri e pā ana ki te whakawātea e whakapaetia ana; (2) whakaahuatanga o te ihirangi e whakapaetia ana e takahi ana me ngā mōhiohio e tika ana kia taea ai e mātou te kimi i te ihirangi; (3) mōhiohio whakapā mōu, tae atu ki tō wāhitau, tau waea me tō wāhitau īmēra; (4) he tauākī nāu e whakapono pono ana koe kāore te ihirangi i te āhua e amuamutia ana i whakamanahia e te kaipupuri mana pupuri, e tana māngai rānei, e te whakahaerenga rānei o tētahi ture; ']

['(5) he tauākī nāu i haina, i raro i te whiu o te whakapae teka, e tika ana ngā mōhiohio i roto i te whakamōhiotanga, ā, kei a koe te mana ki te whakatinana i ngā mana pupuri e kīia ana kua takahia;']

['me te (6) he waitohu ā-tinana, ā-rorohiko rānei a te kaipupuri mana pupuri, a tētahi tangata rānei kua whakamanahia ki te mahi mō te kaipupuri mana pupuri. ']

['Ki te kore e whakaurua ngā mōhiohio katoa i runga ake nei, ka whakaroa pea te tukatuka o tō amuamu.']

['Whakapā']

['Tena koa tukuna mai he imeera ki a maatau me tetahi patai / whakaaro.']

What is prognosis of alzheimer?

The prognosis of Alzheimer's disease is generally poor, as it is a progressive and degenerative condition with no known cure.

The rate of progression varies from person to person, but the disease typically worsens over time, leading to a decline in cognitive and physical abilities.

As the disease progresses, individuals may experience memory loss, difficulty with language and communication, disorientation, and changes in mood and behavior.

Eventually, they may become unable to care for themselves and require full-time assistance.

The average life expectancy after diagnosis is around 8-10 years, but this can vary widely depending on the individual's age, overall health, and other factors.

While there is no cure, treatments and therapies can help manage symptoms and improve quality of life for those with Alzheimer's disease.

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