What is pathophysiology of Lung cancer?

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Quina es la fisiopatologia del càncer del palmon?

La fisiopatologia del càncer del palmon fa referéncia als cambiaments dins los procediments e mecanismes fisiologics normals que se produson dins lo desvelopament e la progression del càncer del palmon.

Lo càncer del palmon es una malautiá complèxa que resulta de la creissença e division descontroladas de cellulas anormalas dins los palmons.

Aquelas cellulas pòdon formar de tumors e s'espandir a d'autras partidas del còs, menant a diferents simptòmas e complicacions.

La fisiopatologia del càncer del palmon implica diferents factors, coma las mutacions geneticas, factors environamentals, e causidas de l'estil de vida.

De mutacions geneticas pòdon se produire dins l'ADN de las cellulas del palmon, menant a una creissença e division cellulara non contrarotlada.

Aquelas mutacions pòdon èsser eretadas o aqueridas, e pòdon èsser causadas per l'exposicion a de cancerigèns, coma lo fum de tabac, radon, amiant, e pollucion de l'aire.

Lo càncer del palmon se pòt classificar en dos tipes principals: lo càncer de palmon de pichona cellula (SCLC) e lo càncer de palmon de pichona cellula (NSCLC).

La fisiopatologia d'aqueles tipes de càncer de palmon pòt diferir, que presentan de mutacions geneticas diferentas e respondon diferentament al tractament.

La fisiopatologia del càncer del palmon implica tanben l'interaccion entre las cellulas cancerosas e lo teissut a l'entorn, amb lo sistèma immunitari.

Las cellulas cancerosas pòdon escapar al sistèma immunitari, lor permetent de créisser e s'espandir sens contraròtle.

Mai, lo microenvironament de la tumor pòt promòure la creissença de la tumor e la metastasi donant un environament favorable per las cellulas cancerosas.

La fisiopatologia del càncer de palmon es un procediment complèxe e dinamic, e los cercaires trabalhan de contunh per comprene melhor los mecanismes de basa per desvolopar de tractaments mai eficaces e melhorar los resultats dels pacients.

['Referéncias']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Li Z, Qian Y, Li W, Liu L, Yu L, Liu X, Wu G, Wang Y, Luo W, Fang F, Liu Y, Song F, Cai Z, Chen W, Huang W: Human Lung Adenocarcinoma-Derived Organoid Models for Drug Screening. iScience. 2020, 23 (8): 101411.

Nurwidya F, Syahruddin E, Yunus F: Pain management in lung cancer. Adv Respir Med. 2016, 84 (6): 331-336.

Khan KA, Kennedy MP, Moore E, Crush L, Prendeville S, Maher MM, Burke L, Henry MT: Radiological characteristics, histological features and clinical outcomes of lung cancer patients with coexistent idiopathic pulmonary fibrosis. Lung. 2015, 193 (1): 71-7.

Paramanantham A, Asfiya R, Das S, McCully G, Srivastava A: Extracellular Vesicle (EVs) Associated Non-Coding RNAs in Lung Cancer and Therapeutics. Int J Mol Sci. 2022, 23 (21): .

Lee D, Kim Y, Chung C: Scientific Validation and Clinical Application of Lung Cancer Organoids. Cells. 2021, 10 (11): .

Mucchietto V, Crespi A, Fasoli F, Clementi F, Gotti C: Neuronal Acetylcholine Nicotinic Receptors as New Targets for Lung Cancer Treatment. Curr Pharm Des. 2016, 22 (14): 2160-9.

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What is pathophysiology of lung cancer?

The pathophysiology of lung cancer refers to the changes in the normal physiological processes and mechanisms that occur in the development and progression of lung cancer.

Lung cancer is a complex disease that arises from the uncontrolled growth and division of abnormal cells in the lungs.

These cells can form tumors and spread to other parts of the body, leading to various symptoms and complications.

The pathophysiology of lung cancer involves several factors, including genetic mutations, environmental factors, and lifestyle choices.

Genetic mutations can occur in the DNA of lung cells, leading to uncontrolled cell growth and division.

These mutations can be inherited or acquired, and they can be caused by exposure to carcinogens, such as tobacco smoke, radon, asbestos, and air pollution.

Lung cancer can be classified into two main types: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC is further divided into three subtypes: adenocarcinoma, squamous cell carcinoma, and large cell carcinoma.

The pathophysiology of these types of lung cancer can differ, as they have different genetic mutations and respond differently to treatment.

The pathophysiology of lung cancer also involves the interaction between cancer cells and the surrounding tissue, including the immune system.

Cancer cells can evade the immune system, allowing them to grow and spread unchecked.

Additionally, the tumor microenvironment can promote tumor growth and metastasis by providing a supportive environment for cancer cells.

The pathophysiology of lung cancer is a complex and dynamic process, and researchers are continuously working to better understand the underlying mechanisms to develop more effective treatments and improve patient outcomes.

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