Inona ny fisiopatolojian'ny homamiadan'ny tsinaibe?
Ny fisiopatolojian'ny homamiadan'ny tsinaibe dia manondro ireo rafitra sy dingana fototra izay mitarika amin'ny fivoarana sy ny fivoaran'ny homamiadan'ny tsinaibe.
Ny homamiadan'ny tsinaibe, fantatra ihany koa amin'ny hoe homamiadan'ny tsinaibe, dia karazana homamiadana izay manomboka ao amin'ny tsinaibe na ny tsinaibe, izay ampahany amin'ny tsinainy lehibe.
Matetika izy io no mipoitra amin'ny voalohany, ary mety hivadika ho kansera rehefa mandeha ny fotoana.
Misy antony maro mahatonga ny homamiadan'ny tsinaibe, toy ny fiovan'ny fototarazo, ny fivontosana, ary ny tontolo iainana.
Mety hisy fiovan'ny fototarazo ao amin'ny ADN ao amin'ny selan'ny tsinaibe, ka miteraka fitomboana sy fizarazarana tsy voafehy.
Mety ho nolovana na nahazoana azy ireny, ary mety hisy vokany eo amin'ny fototarazo samihafa, izay mandray anjara amin'ny fitomboan'ny sela sy ny fizarazarany ary ny fanamboarany.
Mety hampitombo ny mety ho voan'ny kanseran'ny tsinay koa ny fivontosan'ny tsinay, izay mety ho vokatry ny aretina toy ny aretin'ny tsinay.
Mety hivoatra ho kansera ny fivontosana mitaiza, satria mampitombo sy mizara ny sela ny zavatra simika ao amin'ny vatana.
Mety hitarika ny fivoaran'ny homamiadan'ny tsinaibe koa ny tontolo iainana, toy ny sakafo, ny fomba fiaina, ary ny fijerena zavatra simika sasany.
Ny sakafo be hena mena sy voahodina, ohatra, dia mifandray amin'ny fitomboan'ny risika amin'ny homamiadan'ny tsinaibe.
Mety hampitombo ny loza koa ny antony hafa, toy ny hatavezina, ny fifohana sigara, ary ny tsy fanaovana fanatanjahan-tena.
Rehefa mivoatra ny homamiadan'ny tsinaibe, dia afaka mandroso amin'ny dingana maromaro, manomboka amin'ny homamiadana ambaratonga voalohany izay voafetra amin'ny tsinaibe ka hatramin'ny dingana mandroso kokoa izay niparitahan'ny homamiadana tany amin'ny faritra hafa amin'ny vatana.
Mety hiditra any amin'ny taova sy taova eo akaiky eo ny sela misy kansera, ary mety hiparitaka any amin'ny aty na havokavoka.
Ny fitsaboana ny homamiadan'ny tsinaibe dia ahitana fandidiana, fitsaboana simika, ary fitsaboana amin'ny taratra, arakaraka ny dingana sy ny toerana misy ny homamiadana.
Ny fitiliana sy ny fitsaboana aloha no fanalahidin'ny fanatsarana ny vokatra, satria matetika azo sitranina ny homamiadan'ny tsinaibe rehefa tratra amin'ny dingana voalohany.
Mety ho hita aloha be ny kanseran'ny tsinay, rehefa mora tsaboina.
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Yagi T, Kubota E, Koyama H, Tanaka T, Kataoka H, Imaeda K, Joh T: Glucagon promotes colon cancer cell growth via regulating AMPK and MAPK pathways. Oncotarget. 2018, 9 (12): 10650-10664.
Sharma SH, Thulasingam S, Nagarajan S: Terpenoids as anti-colon cancer agents - A comprehensive review on its mechanistic perspectives. Eur J Pharmacol. 2017, 795 (): 169-178.
Keshk WA, Zineldeen DH, Wasfy RE, El-Khadrawy OH: Fatty acid synthase/oxidized low-density lipoprotein as metabolic oncogenes linking obesity to colon cancer via NF-kappa B in Egyptians. Med Oncol. 2014, 31 (10): 192.
Dongfeng D, An C, Shujia P, Jikai Y, Tao Y, Rui D, Kai T, Yafeng C, Jianguo L, Xilin D: Explanation of colon cancer pathophysiology through analyzing the disrupted homeostasis of bile acids. Afr Health Sci. 2014, 14 (4): 925-8.
Tammali R, Ramana KV, Srivastava SK: Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Lett. 2007, 252 (2): 299-306.
['Fialana andraikitra: fitsaboana']
['Natao hampianarana sy hampahafantarana fotsiny ity tranonkala ity, fa tsy natao hanomezana torohevitra ara-pitsaboana na tolotra matihanina.']
['Tsy tokony hampiasaina mba hamantarana na hitsaboana olana ara-pahasalamana na aretina ny fanazavana omena, ary tokony hanatona dokotera manana fahazoan-dalana hitsabo tena ireo mitady torohevitra ara-pitsaboana.']
["Mariho tsara fa ny tambajotra neural izay mamorona ny valin'ny fanontaniana, dia tsy marina indrindra raha resaka isa no resahina. Ohatra, ny isan'ny olona voamarina fa voan'ny aretina manokana."]
["Mitadiava torohevitra avy amin'ny dokotera na mpitsabo hafa mahay momba ny toe-pahasalamanao. Aza atao tsinontsinona mihitsy ny torohevitra ara-pitsaboana matihanina na manemotra ny fikatsahana azy noho ny zavatra novakianao tao amin'ity tranonkala ity. Raha mieritreritra ianao fa mety manana vonjy taitra ara-pitsaboana, antsoy ny 911 na mandehana any amin'ny efitrano fitsaboana maika akaiky indrindra avy hatrany. Tsy misy fifandraisana mpitsabo-marary noforonin'ity tranonkala ity na ny fampiasana azy. Na ny BioMedLib na ny mpiasa ao aminy, na ny mpandray anjara amin'ity tranonkala ity, dia tsy manao fanambarana, mazava na tsy mazava, momba ny fampahalalana omena eto na ny fampiasana azy."]
["Fanamarihana: zon'ny mpamorona"]
["Ny Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (ny DMCA) dia manome vahaolana ho an'ireo tompon'ny zon'ny mpamorona izay mino fa manitsakitsaka ny zony araka ny lalàna momba ny zon'ny mpamorona ao Etazonia ny fitaovana hita ao amin'ny Internet. "]
["Raha mino ianao fa misy votoaty na fitaovana azo ampiasaina amin'ny tranonkalanay na ny tolotra ataonay manitsakitsaka ny zon'ny mpamorona anao, dia afaka mandefa filazana aminay ianao (na ny mpandraharaha anao) mangataka ny hanesorana ny votoaty na ny fitaovana, na ny fanakanana ny fidirana amin'izany. "]
['Tsy maintsy alefa an-tsoratra amin\'ny alalan\'ny mailaka ny filazana (jereo ny fizarana "Contact" raha mila adiresy mailaka). ']
["Ny DMCA dia mitaky ny fampandrenesanao ny voalaza ho fanitsakitsahana ny zon'ny mpamorona ahitana ireto fampahalalana manaraka ireto: (1) famaritana ny asa voaaro zon'ny mpamorona izay voalaza fa voahitsakitsaka; (2) famaritana ny votoaty voalaza fa manitsakitsaka sy fampahalalana ampy ahafahantsika mahita ny votoatiny; (3) fampahalalana momba anao, anisan'izany ny adiresinao, nomeraon-telefaona ary adiresy mailaka; (4) fanambarana avy aminao fa mino tsara ianao fa ny votoaty amin'ny fomba nitarainana dia tsy nomen'ny tompon'ny zon'ny mpamorona alalana, na ny mpandraharahany, na amin'ny asan'ny lalàna rehetra; "]
["(5) fanambarana nosoniavinao, eo ambany sazin'ny fianianana diso, fa marina ny vaovao ao amin'ny fampahafantarana ary manana fahefana hampihatra ny zon'ny mpamorona izay voalaza fa voahitsakitsaka ianao; "]
["Mety hiteraka fahatarana amin'ny fikarakarana ny fitarainanao ny tsy fampidirana ireo vaovao rehetra voalaza etsy ambony."]
['Fifandraisana']
['Alefaso mailaka izahay raha misy fanontaniana / sosokevitra.']
What is pathophysiology of colon cancer?
The pathophysiology of colon cancer refers to the underlying mechanisms and processes that lead to the development and progression of colon cancer.
Colon cancer, also known as colorectal cancer, is a type of cancer that begins in the colon or rectum, which are parts of the large intestine.
It typically starts as a growth called a polyp, which can develop into cancer over time.
The pathophysiology of colon cancer involves several factors, including genetic mutations, inflammation, and environmental factors.
Genetic mutations can occur in the DNA of colon cells, leading to uncontrolled cell growth and division.
These mutations can be inherited or acquired, and they can affect various genes involved in cell growth, division, and repair.
Inflammation in the colon, which can be caused by conditions such as inflammatory bowel disease, can also increase the risk of colon cancer.
Chronic inflammation can lead to the release of chemicals that promote cell growth and division, potentially leading to the development of cancer.
Environmental factors, such as diet, lifestyle, and exposure to certain chemicals, can also contribute to the development of colon cancer.
A diet high in red and processed meats, for example, has been linked to an increased risk of colon cancer.
Other factors, such as obesity, smoking, and lack of physical activity, can also increase the risk.
Once colon cancer develops, it can progress through several stages, from early-stage cancer that is confined to the colon to more advanced stages where the cancer has spread to other parts of the body.
The cancer cells can invade nearby tissues and organs, and may also spread through the lymphatic system or bloodstream to distant sites, such as the liver or lungs.
Treatment for colon cancer typically involves a combination of surgery, chemotherapy, and radiation therapy, depending on the stage and location of the cancer.
Early detection and treatment are key to improving outcomes, as colon cancer is often curable when caught in its early stages.
Regular screening, such as colonoscopy, can help detect colon cancer at its earliest stages, when it is most treatable.
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['Manodidina ny']
['Mampiasa solosaina mandeha ho azy (algoritma fianarana milina) ny BioMedLib mba hamoronana fanontaniana sy valiny.']
["Manomboka amin'ny famoahana biomedika 35 tapitrisa ao amin'ny PubMed/Medline izahay. ary koa ny pejin'ny tranonkala RefinedWeb."]
