O le pathophysiology o le maʻi suka e faasino atu i le suʻesuʻeina o le le lelei o le tino o le tino e mafua ai le atinaʻeina o le maʻisuka.
O le maʻi suka, o se ituaiga o gasegase e māfua ona o le maualuga o le suka i le toto (glucose) e māfua mai i le lē lelei o le faamatuu atu o le inisalini, po o le lē lelei foʻi o le gaoioiga o le inisalini.
O le pathophysiology o le maʻi suka e aofia ai le fesootaʻiga lavelave o mea tau kenera, siʻosiʻomaga, ma le olaga e aafia ai le atinaʻeina o le maʻi.
I le maʻi suka ituaiga 1, o le pathophysiology e aofia ai le faaleagaina o sela beta e gaosia ai le inisalini i le pancreas, ma iʻu ai i le lē lava o le inisalini.
O le iʻuga, e lē mafai ona pulea le kulukose o le toto, ma oo ai ina maualuga le suka i le toto.
I le maʻi suka ituaiga 2, e sili atu ona faigatā le faiga o le tino ma e aafia ai le tetee i le inisalini ma le lē mafai ona faamatuu atu le inisalini.
O le tetee atu i le inisalini e tupu pe a lē tali lelei sela o le tino i le inisalini, ma lē mafai ai ona faaaogā lelei le kulukose e maua ai le malosi.
O le iʻuga, e tele le insulin e maua mai i le pancreas e taumafai ai e foʻia le faafitauli, ae a o faagasolo taimi, e lē mafai e le pancreas ona gaosia le insulin e manaʻomia, ma iʻu ai ina faaitiitia le insulin.
O le maʻi suka o le maʻitaga, lea e tupu a o maʻitaga, e māfua mai i suiga o le homone lea e māfua ai le tetee i le inisalini.
E maua mai i le placenta ni homone e mafai ona taofia ai le galuega a le inisalini, ma iʻu ai ina faateleina le suka i le toto.
O le pathophysiology o le maʻi suka e aofia ai foʻi le atinaʻeina o faʻafitauli, e pei o le faʻaleagaina o toto toto, neula, ma totoga, lea e mafai ona oʻo atu ai i faʻafitauli ogaoga o le soifua maloloina e pei o le fatu, stroke, fatugaʻo maʻi, ma le leiloa o le vaʻai.
O le malamalama i le pathophysiology o le maʻi suka, e tāua tele i le faia o togafitiga ma auala e puipuia ai lenei maʻi faaumiumi.
Biochemistry and pathophysiology of diabetes. Proceedings of conference on pathophysiology and treatment of diabetes mellitus. 1990. Mol Cell Biochem. 1992, 109 (2): 97-204.
Surampudi PN, John-Kalarickal J, Fonseca VA: Emerging concepts in the pathophysiology of type 2 diabetes mellitus. Mt Sinai J Med. 2009, 76 (3): 216-26.
Johnson D: Selected pathophysiology of diabetes. Semin Perioper Nurs. 1998, 7 (3): 164-78.
Hirsch IB: The changing faces of diabetes. Prim Care. 2003, 30 (3): 499-510.
Guthrie RA, Guthrie DW: Pathophysiology of diabetes mellitus. Crit Care Nurs Q. , 27 (2): 113-25.
Felig P: Pathophysiology of diabetes mellitus. Med Clin North Am. 1971, 55 (4): 821-34.
['Faamatalaga: faafomaʻi']
['O lenei upega tafaʻilagi ua saunia mo na o le aʻoaʻoina ma le faailoaina atu o faamatalaga, ae e lē o se fautuaga faafomaʻi po o se auaunaga faapolofesa.']
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['(5) o se faamatalaga mai iā te oe, ua sainia i lalo o le faasalaga o le pepelo, e faapea o faamatalaga o loo i le faasilasilaga e saʻo ma e iai lau pule e faamalosia ai le aiā tatau lea o loo faapea mai ua solia; ']
['ma le (6) saini faaletino po o saini faaeletoroni a lē e ana le aiā tatau po o se tagata ua faatagaina e galue e fai ma sui o lē e ana le aiā tatau. ']
['Afai e lē o aofia uma faamatalaga o loo i luga, e ono faatuai ai ona iloilo lau faitioga.']
['Faafesootaʻi']
['Faamolemole lafo mai se imeli i so o se fesili / fautuaga.']
What is pathophysiology of diabetes?
Pathophysiology of diabetes refers to the study of the disordered physiological processes that lead to the development of diabetes mellitus.
Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels that result from defects in insulin secretion, insulin action, or both.
The pathophysiology of diabetes involves the complex interplay of genetic, environmental, and lifestyle factors that contribute to the development of the disease.
In type 1 diabetes, the pathophysiology involves an autoimmune destruction of the insulin-producing beta cells in the pancreas, leading to a deficiency in insulin production.
This results in an inability to regulate blood glucose levels, leading to hyperglycemia (high blood sugar).
In type 2 diabetes, the pathophysiology is more complex and involves both insulin resistance and impaired insulin secretion.
Insulin resistance occurs when the body's cells do not respond properly to insulin, leading to an inability to effectively use glucose for energy.
This causes the pancreas to produce more insulin to try to overcome the resistance, but over time, the pancreas may not be able to keep up with the demand, leading to a decrease in insulin production.
Gestational diabetes, which occurs during pregnancy, is caused by hormonal changes that lead to insulin resistance.
The placenta produces hormones that can block the action of insulin, leading to an increase in blood glucose levels.
The pathophysiology of diabetes also involves the development of complications, such as damage to blood vessels, nerves, and organs, which can lead to serious health problems like heart disease, stroke, kidney disease, and vision loss.
Understanding the pathophysiology of diabetes is crucial for developing effective treatments and prevention strategies for this chronic disease.
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['Tagaʻi i le "Faamatalaga" ma le "Faamatalaga".']
