Lefu la Alzheimer le fumanoa ka mekhoa e mengata, ho akarelletsa le tlhahlobo e feletseng ea bongaka, liteko tsa kelello le tsa methapo ea kutlo, ho hlahloba boko le ho tlosa lintho tse ling tse ka 'nang tsa baka lefu lena.
1. Tlhahlobo ea bongaka: Ngaka e tla hlahloba'mele oa hao le ho hlahloba ka ho qaqileng hore na u kile ua tšoaroa ke eng e le hore e fumane hore na ho na le lintho tse ling tse ka etsang hore u lebale kapa u se ke ua khona ho etsa lintho tse itseng, tse kang mathata a qoqotho, ho haella ha livithamine kapa lihlahala tsa boko.
2. Liteko tsa kelello le tsa methapo ea kutlo: Liteko tsena li hlahloba ho hopola lintho, puo, ho rarolla mathata le mesebetsi e meng ea kelello ho fumana hore na boko bo senyehile hakae le ho khetholla pakeng tsa ho lebala lintho ka lebaka la ho tsofala le 'dementia.'
3. Ho nka litšoantšo tsa boko: Ho nka litšoantšo tsa matla a khoheli (MRI) kapa ho etsa litšoantšo tsa matla a khoheli (CT) ho ka thusa ho khetholla liphetoho tsa sebopeho sa boko tse ka 'nang tsa bontša lefu la Alzheimer.
Ho ka boela ha sebelisoa mokhoa oa ho hlahloba ka positron emission tomography (PET) ho bona hore na ho na le liprotheine tse itseng tse amanang le lefu la Alzheimer's.
4. Liteko tsa mali: Lipatlisiso tsa morao tjena li bontšitse hore ho hlahloba mali ho ka thusa ho fumana lefu la Alzheimer ka ho lekanya liprotheine tse itseng kapa lintho tse tšoaeang lefu lena.
5. Mokhoa oa ho tlosa: Kaha ha ho na mokhoa o le mong o ka khethollang lefu la Alzheimer, hangata ho hlahloba lefu lena ho akarelletsa ho tlosa lisosa tse ling tse ka 'nang tsa baka matšoao a kang a 'dementia.'
Ke habohlokoa ho hlokomela hore ho ka etsoa tlhahlobo e hlakileng ea lefu la Alzheimer feela ka mor'a lefu ka ho hlahloba lisele tsa boko.
Leha ho le joalo, mekhoa ea hona joale ea ho hlahloba mafu e ka fana ka bopaki bo tiileng ba hore motho o na le lefu lena ha a ntse a phela.
Ho bohlokoa hore motho a fumanoe a sa le monyenyane e le hore a ka qala ho phekoloa le ho rera bokamoso.
Liu SS, Zhu SQ: [Correlation between Alzheimer disease and cataract]. Zhonghua Yan Ke Za Zhi. 2017, 53 (4): 314-316.
Gauthier S: Practical guidelines for the antemortem diagnosis of senile dementia of the Alzheimer type. Prog Neuropsychopharmacol Biol Psychiatry. 1985, 9 (5-6): 491-5.
Rubin R: New Test to Help Diagnose Alzheimer Disease. JAMA. 2022, 327 (23): 2281.
[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.
Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.
Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.
Volicer L, Berman SA, Cipolloni PB, Mandell A: Persistent vegetative state in Alzheimer disease. Does it exist? Arch Neurol. 1997, 54 (11): 1382-4.
Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.
Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.
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['(5) polelo e saennweng ke wena, tlasa kotlo ya ho hlapanya leshano, ya hore tlhahisoleseding e tsebisong e nepahetse le hore o na le matla a ho tiisa ditokelo tsa mongodi tseo ho thweng di a tlolwa; ']
["le (6) ho saena ka letsoho kapa ka elektronike ha mong'a litokelo tsa bangoli kapa motho ea lumeletsoeng ho nka khato lebitsong la mong'a litokelo tsa bangoli. "]
['Ho hloleha ho kenyelletsa tlhahisoleseding yohle e ka hodimo ho ka baka ho dieha ha ho sebetswa tletlebo ya hao.']
['Ho Iteanya']
['Ka kōpo re romelle imeile ka potso / tlhahiso leha e le efe.']
How is alzheimer diagnosed?
Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.
1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.
2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.
3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.
Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.
4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.
5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.
It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.
However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.
Early diagnosis is important for starting treatment and planning for the future.
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