Lefu la Alzheimer ke lefu le tsoelang pele la ho senyeha ha methapo ea kutlo le amang boko haholo, le baka ho lahleheloa ke mohopolo, ho fokotseha ha matla a kelello le ho fetoha ha boitšoaro.
Sesosa se tobileng sa lefu la Alzheimer ha se utloisisoe ka botlalo, empa ho lumeloa hore se bakoa ke lintho tse itseng tse amanang le liphatsa tsa lefutso, tikoloho le tsela eo motho a phelang ka eona.
Lintlha tse ling tse ka 'nang tsa tlatsetsa ho hlahiseng lefu la Alzheimer li akarelletsa:
1. Liphatsa tsa lefutso: Ho fumanoe liphatsa tse itseng tsa lefutso tse eketsang kotsi ea ho tšoaroa ke lefu la Alzheimer, haholo - holo liphatsa tsa lefutso tsa apolipoprotein E (APOE).
2. Lilemo: Kotsi ea ho tšoaroa ke lefu la Alzheimer e eketseha ha motho a ntse a hōla,'me boholo ba batho ba fumanoa ba e-na le lefu lena ha ba se ba le lilemo li 65.
3. Histori ea lelapa: Ho ba le histori ea lelapa ea lefu la Alzheimer ho ka eketsa kotsi ea ho ba le boemo bona.
4. Ho lemala hloohong: Ho lemala hloohong nakong e fetileng, haholo-holo ho bakang ho akheha, ho ka eketsa kotsi ea lefu la Alzheimer.
5. Lintho tse ka bakang lefu la pelo: Maemo a kang khatello e phahameng ea mali, k'holeseterole e ngata le lefu la tsoekere a ka eketsa kotsi ea ho tšoaroa ke lefu la Alzheimer.
6. Lintho tse amang tsela eo motho a phelang ka eona: Ho lula fatše, ho se je hantle le ho se sebetse hantle kelellong ho ka eketsa kotsi ea ho tšoaroa ke lefu la Alzheimer.
7. Ho ruruha: Ho ruruha ho sa foleng bokong ho ka 'na ha tlatsetsa ho hlaheng ha lefu la Alzheimer.
8. Khatello ea kelello e bakoang ke ho kenella ha mafura a mangata'meleng: Ho se leka-lekane pakeng tsa ho hlahisa li-radical le bokhoni ba'mele ba ho li ntša chefo ho ka 'na ha etsa hore motho a be le lefu la Alzheimer.
9. Li-plaque tsa amyloid le li-tangles tsa neurofibrillary: Ho bokellana ha li-plaque tsa amyloid le li-tangles tsa neurofibrillary bokong ke letšoao la lefu la Alzheimer, empa karolo eo li e phethang ho hlahiseng boemo bona ha e utloisisoe ka botlalo.
Ke habohlokoa ho hlokomela hore sesosa sa lefu la Alzheimer se rarahane'me mohlomong se akarelletsa ho kopana ha lintho tsena.
Ho ntse ho etsoa lipatlisiso ho utloisisa hantle hore na ke hobane'ng ha ho etsahala sena le ho fumana mekhoa e sebetsang ea ho phekola lefu lena le kotsi.
Vellas B, Andrieu S, Cantet C, Dartigues JF, Gauthier S: Long-term changes in ADAS-cog: what is clinically relevant for disease modifying trials in Alzheimer? J Nutr Health Aging. , 11 (4): 338-41.
Braak E, Griffing K, Arai K, Bohl J, Bratzke H, Braak H: Neuropathology of Alzheimer's disease: what is new since A. Alzheimer? Eur Arch Psychiatry Clin Neurosci. 1999, 249 Suppl 3 (): 14-22.
Kovacs GG: Can Creutzfeldt-Jakob disease unravel the mysteries of Alzheimer? Prion. 2016, 10 (5): 369-376.
Cankurtaran M, Yavuz BB, Cankurtaran ES, Halil M, Ulger Z, Ariogul S: Risk factors and type of dementia: vascular or Alzheimer? Arch Gerontol Geriatr. , 47 (1): 25-34.
Mahami-Oskouei M, Hamidi F, Talebi M, Farhoudi M, Taheraghdam AA, Kazemi T, Sadeghi-Bazargani H, Fallah E: Toxoplasmosis and Alzheimer: can Toxoplasma gondii really be introduced as a risk factor in etiology of Alzheimer? Parasitol Res. 2016, 115 (8): 3169-74.
['Tlhokomeliso: tsa bongaka']
["Websaete ena e etselitsoe ho ruta le ho fana ka boitsebiso feela'me ha e fane ka keletso ea bongaka kapa litšebeletso tsa litsebi."]
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['Ka kōpo hlokomela hore neural net e hlahisang likarabo lipotsong, ha e nepahale haholo-holo ha ho tluoa linomorong.']
["Kamehla batla keletso ea ngaka ea hao kapa mofani e mong ea tšoanelehang oa tlhokomelo ea bophelo mabapi le boemo ba bongaka. Le ka mohla u se ke ua hlokomoloha keletso ea setsebi sa bongaka kapa ua lieha ho e batla ka lebaka la ntho eo u e balileng websaeteng ena. Haeba u nahana hore u ka 'na ua ba le boemo ba tšohanyetso ba bongaka, letsetsa 911 kapa u ee kamoreng ea tšohanyetso e haufi hang-hang. Ha ho kamano ea ngaka le mokuli e bōptjoang ke websaeteng ena kapa tšebeliso ea eona. BioMedLib kapa basebetsi ba eona, kapa motho leha e le ofe ea tlatsetsang ho websaeteng ena, ha a etse litemoso, tse hlakileng kapa tse sa hlakang, mabapi le boitsebiso bo fanoeng mona kapa tšebeliso ea eona."]
['Tlhokomeliso: litokelo tsa bangoli']
['Molao oa Digital Millennium Copyright Act oa 1998, 17 U.S.C. § 512 (DMCA) o fana ka litokelo tsa beng ba litokelo tsa bangoli ba lumelang hore thepa e hlahang Inthaneteng e hatakela litokelo tsa bona tlasa molao oa litokelo tsa bangoli ba U.S. ']
['Haeba u lumela ka tumelo e ntle hore litaba leha e le life kapa thepa e fumanehang mabapi le websaeteng kapa litšebeletso tsa rona e tlōla litokelo tsa hau tsa molao, uena (kapa moemeli oa hau) a ka re romella tsebiso e kōpang hore litaba kapa thepa e tlosoe, kapa ho fihlella ho eona ho thibeloe. ']
['Ditsebiso di tlameha ho romelwa ka lengolo ka imeile (bona karolo ya "Ho iteanya" bakeng sa aterese ya imeile). ']
["DMCA e hloka hore tsebiso ea hao ea ho tlōla ha molao ho boleloang hore e na le boitsebiso bo latelang: (1) tlhaloso ea mosebetsi o sirelelitsoeng ka molao o boleloang hore o tlōloa; (2) tlhaloso ea litaba tse boleloang hore li tlōla molao le boitsebiso bo lekaneng ho re lumella ho fumana litaba; (3) boitsebiso ba ho ikopanya le uena, ho akarelletsa aterese ea hau, nomoro ea fono le aterese ea imeile; (4) polelo ea hau ea hore u na le tumelo e ntle ea hore litaba ka tsela e belaelloang ha e lumelloe ke mong'a litokelo tsa molao, kapa moemeli oa eona, kapa ka ts'ebetso ea molao leha e le ofe; "]
['(5) polelo e saennweng ke wena, tlasa kotlo ya ho hlapanya leshano, ya hore tlhahisoleseding e tsebisong e nepahetse le hore o na le matla a ho tiisa ditokelo tsa mongodi tseo ho thweng di a tlolwa; ']
["le (6) ho saena ka letsoho kapa ka elektronike ha mong'a litokelo tsa bangoli kapa motho ea lumeletsoeng ho nka khato lebitsong la mong'a litokelo tsa bangoli. "]
['Ho hloleha ho kenyelletsa tlhahisoleseding yohle e ka hodimo ho ka baka ho dieha ha ho sebetswa tletlebo ya hao.']
['Ho Iteanya']
['Ka kōpo re romelle imeile ka potso / tlhahiso leha e le efe.']
What causes alzheimer?
Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects the brain, causing memory loss, cognitive decline, and behavioral changes.
The exact cause of Alzheimer's disease is not fully understood, but it is believed to result from a combination of genetic, environmental, and lifestyle factors.
Some of the factors that may contribute to the development of Alzheimer's disease include:
1. Genetics: Certain genes have been identified that increase the risk of developing Alzheimer's disease, particularly the apolipoprotein E (APOE) gene.
2. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.
3. Family history: Having a family history of Alzheimer's disease may increase the risk of developing the condition.
4. Head injuries: A history of head injuries, particularly those that result in loss of consciousness, may increase the risk of Alzheimer's disease.
5. Cardiovascular risk factors: Conditions such as high blood pressure, high cholesterol, and diabetes may increase the risk of developing Alzheimer's disease.
6. Lifestyle factors: A sedentary lifestyle, poor diet, and lack of mental stimulation may increase the risk of Alzheimer's disease.
7. Inflammation: Chronic inflammation in the brain may contribute to the development of Alzheimer's disease.
8. Oxidative stress: An imbalance between the production of free radicals and the body's ability to detoxify them may contribute to the development of Alzheimer's disease.
9. Amyloid plaques and neurofibrillary tangles: The accumulation of amyloid plaques and neurofibrillary tangles in the brain is a hallmark of Alzheimer's disease, but the role they play in the development of the condition is not fully understood.
It is important to note that the cause of Alzheimer's disease is complex and likely involves a combination of these factors.
Research is ongoing to better understand the underlying mechanisms and develop effective treatments for this devastating condition.
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['Hoo e ka bang']
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['Re qala ka lingoliloeng tse limilione tse 35 tsa biomedical tsa PubMed/Medline. Hape, maqephe a websaete a RefinedWeb.']
