How to treat Prostate cancer?

['Lalela lelikhasi']

Ungayelapha njani umdlavuza we-prostate?

Kunetindlela letehlukene tekwelapha umdlavuza wendlala yesinye, kuye ngesigaba kanye nekuhlaselwa nguwo, kanye nemphilo yesigulane kanye naloko lesikutsandzako.

Letinye tindlela tekwelapha letivamile tifaka ekhatsi:

1. Kulawulwa ngekucophelela: Lendlela ifaka ekhatsi kuhlolwa kwekhensa ngekushesha ngekuhlolwa njalo, kunekutsi kucale kwelashwa ngekushesha.

Kungaba lusito emadvodzeni lanematfuba lamancane ekungenwa ngumdlavuza we-prostate.

2. Kuhlindvwa: Kuhlindvwa kwenyongo kuyindlela yekuhlindvwa kute kususwe lendlala.

Loku kungentiwa ngekuhlindvwa lokuvulekile nobe nge-laparoscopy (kusetjentiswa tintfo letincane kanye nemathulusi lakhetsekile).

3. Kwelapha ngemisebe: Lokwelapha kusebentisa imisebe lenemandla lamakhulu kute kubulawe tinhlayiya temdlavuza.

Ingasetjentiswa ngaphandle kwemtimba (ngemshini losemtimbeni) nobe ngekhatsi (ngekuhlanyela lokubekwe eceleni kwesimila).

4. Kwelashwa ngemahomoni: Lokwelashwa kunciphisa emazinga emahomoni esilisa (androgen) emtimbeni, lokungabangela kutsi umdlavuza we-prostate unciphe nobe umise kukhula kwawo.

Ingasetjentiswa yodvwa nobe ihlanganiswe naletinye tindlela tekwelapha.

5. Kwelapha ngemakhemikhali: Kulendlela yekwelapha kusetjentiswa imitsi kute kubulawe tinhlayiya temdlavuza.

Ingasetjentiswa kumdlavuza wendlala yesinye losakateke nakuletinye tincenye temtimba.

6. Immunotherapy: Loluhlobo lwekwelapha lusita emasotja emtimba kutsi alwisane nemdlavuza.

Ingasetjentiswa kumdlavuza wendlala yesinye losengakabi nemiphumela lebonakalako kuletinye tindlela tekwelapha.

7. Kwelapha lokugcile: Lokwelapha kuhloswe ngemagciwane latsite nobe ngemaphrotheni lasita tinhlayiya temdlavuza kutsi tikhule futsi tiphile.

Ingasetjentiswa kumdlavuza wendlala yesinye losengakabi nemiphumela lebonakalako kuletinye tindlela tekwelapha.

8. Cryotherapy: Loluhlobo lwekwelapha lusebentisa kubandza kakhulu kute kubandze futsi kubulale tinhlayiya temdlavuza.

Ingasetjentiswa kumdlavuza we-prostate losesigabeni sekucala nobe kumdlavuza lovuseleleke ngemuva kwekwelashwa ngalenye indlela.

9. High-intensity focused ultrasound (HIFU): Loluhlelo lusebentisa emagagasi emsindvo lasetulu kute kushise futsi kubhujiswe tinhlayiya temdlavuza.

Ingasetjentiswa kumdlavuza we-prostate losesigabeni sekucala nobe kumdlavuza lovuseleleke ngemuva kwekwelashwa ngalenye indlela.

10. Kulalelwa kwekwelashwa: Lendlela ifaka ekhatsi kulandzelela umdlavuza ngekuhlola njalo, kodvwa ungacali kwelashwa ngaphandle nangabe kuvela timphawu nobe tingashintji.

Kungaba lusito emadvodzeni lamadzala lanesifo semdlavuza we-prostate lokhula kancane kanye naletinye tifo letinkhulu.

Kubalulekile kucoca ngawo onkhe emacebo ekwelapha nelicembu letemphilo kute kuncunywe indlela lekahle yekwelapha simo ngasinye.

['Tintfo letibhalwe phansi']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.

Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.

Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.

Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.

Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.

de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.

Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.

['Sitatimende: setekwelapha']

['Lelikhasi langcondvomshini liniketelwe kufundzisa nekwatisa kuphela futsi alitsatsi seluleko setekwelapha nobe umsebenti wetingcweti.']

['Lemininingwane leniketwako akukafaneli isetjentiselwe kutfola nobe kwelapha tinkinga temphilo nobe tifo, futsi labo labafuna lusito lwetekwelapha kufanele batsintse dokotela lonemvume yekwenta njalo.']

['Uyacelwa kutsi ucaphele kutsi luhlelo lwekuchumana lolwakha timphendvulo temibuto, alukabi kahle kakhulu uma kukhulunywa ngetinombolo. Sibonelo, sibalo sebantfu labanesifo lesitsite.']

['Ngaso sonkhe sikhatsi cela seluleko kudokotela wakho nobe lomunye loniketa lusito lwetemphilo mayelana nesimo sakho sekugula. Ungalokotsi unganaki seluleko sebucwepheshe nobe wephute kusitfola ngenca yalokutsite lokufundze kulewebhusayithi. Uma ucabanga kutsi kungenteka unekugula, shayela 911 nobe uye egunjini lelisedvute lekuphutfuma ngekushesha. Kute budlelwane emkhatsini wetekwelapha nesigulane lobentiwa ngulewebhusayithi nobe kusetjentiswa kwayo. I-BioMedLib nobe basebenti bayo, nobe ngumuphi umuntfu lofaka sandla kulewebhusayithi, akenti nobe nguyiphi imiculu, lechazako nobe lechazako, mayelana nemniningwane loniketwe lapha nobe kusetjentiswa kwayo.']

['Liciniso: copyright']

['Umtsetfo we-Digital Millennium Copyright Act wanga-1998, 17 U.S.C. § 512 (i-DMCA) uniketa indlela yekusitwa kubanikati bemalungelo ekushicilela labakholelwa kutsi tintfo letivela ku-Internet tiphula emalungelo abo ngaphansi kwemtsetfo we-U.S. wekushicilela. ']

['Nangabe ukholelwa kutsi nobe nguyiphi intfo nobe intfo lekhona kulewebhusayithi nobe etinhlelweni tetfu yephula emalungelo akho, wena (nobe ummeli wakho) ungasitfumelela satiso ucele kutsi leyo nto nobe intfo isuswe nobe ivinjelwe.']

['Tatiso kumele titfunyelwe nge-email (buka likheli le-email kusigaba "Sekuchumana").']

['I-DMCA idzinga kutsi satiso sakho sekuhlukumeta emalungelo eluntfu sicukatse lemininingwane lelandzelako: (1) inchazelo yemsebenti logunyatwe emalungelo eluntfu lokutsiwa uphasiwe; (2) inchazelo yalokucuketfwe lokutsiwa kuphasiwe kanye nemininingwane leyenele kutsi sikhone kutfola lokucuketfwe; (3) imininingwane yekutsintsana nawe, kufaka ekhatsi likheli lakho, inombolo yelucingo nelikheli le-email; (4) sitatimende sakho sekutsi unenkolelo lenhle yekutsi lokucuketfwe ngendlela lokhonjiwe akukavumeleki kumnikati wemalungelo eluntfu, nobe kummeli wakhe, nobe ngekusebenta kwanoma ngumuphi umtsetfo; ']

['(5) sitatimende sakho, lesisayinwe ngaphasi kwesijeziso sekufunga emanga, sekutsi umniningwane lokuso satiso ucinisile nekutsi uneligunya lekuvikela emalungelo e-copyright lasolwa kutsi ephuliwe;']

['kanye (6) nekusayina ngekwemtimba nobe nge-elekthroniki kwemnikati we-copyright nobe umuntfu logunyatiwe kutsi ente umsebenti egameni lemnikati we-copyright. ']

['Kwehluleka kufaka yonkhe lemininingwane lengenhla kungaholela ekubambelekeni kwekusetjentwa kwesikhalo sakho.']

['Kuchumana']

['Sicela usitfumelele i-email nganobe nguwuphi umbuto / umbono.']

How to treat prostate cancer?

There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.

Some common treatments include:

1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.

It may be suitable for men with low-risk prostate cancer.

2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.

It can be done through open surgery or laparoscopically (using small incisions and specialized tools).

3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.

It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).

4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.

It can be used alone or in combination with other treatments.

5. Chemotherapy: This treatment uses drugs to kill cancer cells.

It may be used for advanced prostate cancer that has spread to other parts of the body.

6. Immunotherapy: This treatment helps the immune system fight cancer.

It may be used for advanced prostate cancer that has not responded to other treatments.

7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.

It may be used for advanced prostate cancer that has not responded to other treatments.

8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.

It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.

10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.

It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.

It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.

Disclaimer: medical

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