What causes Prostate cancer?

Yini lebangela umdlavuza we-prostate?

Imbangela ye-prostate cancer ayatiwa, kodvwa kunetintfo letinyenti letatfolwa letingenta kutsi ube sengotini yekungenwa ngulesifo.

Loku kufaka ekhatsi:

1. Budzala: Ingoti yekutsi umuntfu abe nemdlavuza wendlala yemtimba iyakhula njengobe achubeka akhula, futsi lamadvodza lamanyenti aneminyaka lengetulu kwa-65 budzala.

2. Umlandvo wemndeni: Emadvodza lanemlandvo wemndeni lonesifo semdlavuza wendlala yesinye, ikakhulukati babe nobe umnakabo lonaso, asengotini lenkhulu.

3. Buve: Emadvodza aseMelika lanemabala lamnyama asengotini lenkhulu yekungenwa ngumdlavuza wendlala yesinye kwendlula emadvodza aletinye tive.

4. Kudla: Kudla lokunemafutsa lamanyenti, ikakhulukati emafutsa etilwane, kungakhulisa ingoti yekutsi ube nemdlavuza wesinye.

5. Kukhuluphala: Kuba nesisindvo lesengetiwe nobe kukhuluphala kakhulu kungakhulisa ematfuba ekungenwa ngumdlavuza wesinye.

6. Ema-hormone: Kuba nemazinga lasetulu e-testosterone nalamanye ema-hormone langena emadvodzeni kungakhulisa ingoti yekutsi ube nemdlavuza wesinye.

7. Kuvuvuka: Kuvuvuka lokungapheli kwesinye, njengesifo semdlavuza wemdlavuza, kungakhulisa ingoti yekutsi ube nawo.

8. Tintfo letitfolakala emakhweni: Kugucuka lokutsite kwemakhwa, njengaloko lokutfolakala ku-BRCA1 naku-BRCA2, kungakhulisa ematfuba ekutsi ube nemdlavuza wesinye.

Kubalulekile kwati kutsi kuba nayinye nobe ngetulu yaletintfo letiyingoti akusho kutsi indvodza itawuba nemdlavuza wendlala yesinye, kantsi emadvodza lamanyenti lanemdlavuza wendlala yesinye ete tintfo letiyingoti letatiwako.

Ngetulu kwaloko, lucwaningo luyachubeka kute kucondvwe kahle loko lokubangela umdlavuza we-prostate kanye netintfo letingabangela kutsi ube khona.

['Tintfo letibhalwe phansi']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Riihimäki M, Thomsen H, Brandt A, Sundquist J, Hemminki K: What do prostate cancer patients die of? Oncologist. 2011, 16 (2): 175-81.

Gilligan T: Social disparities and prostate cancer: mapping the gaps in our knowledge. Cancer Causes Control. 2005, 16 (1): 45-53.

Newschaffer CJ, Otani K, McDonald MK, Penberthy LT: Causes of death in elderly prostate cancer patients and in a comparison nonprostate cancer cohort. J Natl Cancer Inst. 2000, 92 (8): 613-21.

Frydenberg M, Wijesinha S: Diagnosing prostate cancer - what GPs need to know. Aust Fam Physician. 2007, 36 (5): 345-7.

Shimodaira K, Nakashima J, Nakagami Y, Hirasawa Y, Hashimoto T, Satake N, Gondo T, Namiki K, Ohori M, Ohno Y: Prognostic Value of Platelet Counts in Patients with Metastatic Prostate Cancer Treated with Endocrine Therapy. Urol J. 2020, 17 (1): 42-49.

Martínez-Salamanca JI, Ballesteros CM, Carballido Rodríguez J: [Epidemiological fundamentals of clinically localized prostate cancer]. Arch Esp Urol. 2011, 64 (8): 703-10.

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['I-DMCA idzinga kutsi satiso sakho sekuhlukumeta emalungelo eluntfu sicukatse lemininingwane lelandzelako: (1) inchazelo yemsebenti logunyatwe emalungelo eluntfu lokutsiwa uphasiwe; (2) inchazelo yalokucuketfwe lokutsiwa kuphasiwe kanye nemininingwane leyenele kutsi sikhone kutfola lokucuketfwe; (3) imininingwane yekutsintsana nawe, kufaka ekhatsi likheli lakho, inombolo yelucingo nelikheli le-email; (4) sitatimende sakho sekutsi unenkolelo lenhle yekutsi lokucuketfwe ngendlela lokhonjiwe akukavumeleki kumnikati wemalungelo eluntfu, nobe kummeli wakhe, nobe ngekusebenta kwanoma ngumuphi umtsetfo; ']

['(5) sitatimende sakho, lesisayinwe ngaphasi kwesijeziso sekufunga emanga, sekutsi umniningwane lokuso satiso ucinisile nekutsi uneligunya lekuvikela emalungelo e-copyright lasolwa kutsi ephuliwe;']

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['Kwehluleka kufaka yonkhe lemininingwane lengenhla kungaholela ekubambelekeni kwekusetjentwa kwesikhalo sakho.']

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['Sicela usitfumelele i-email nganobe nguwuphi umbuto / umbono.']

What causes prostate cancer?

The exact cause of prostate cancer is not known, but several factors have been identified that may increase the risk of developing the disease.

These include:

1. Age: The risk of prostate cancer increases with age, with most cases occurring in men over the age of 65.

2. Family history: Men with a family history of prostate cancer, particularly a father or brother with the disease, are at a higher risk.

3. Race: African American men have a higher risk of developing prostate cancer than men of other races.

4. Diet: A diet high in fat, particularly animal fat, may increase the risk of prostate cancer.

5. Obesity: Being overweight or obese may increase the risk of developing prostate cancer.

6. Hormones: High levels of testosterone and other male hormones may increase the risk of prostate cancer.

7. Inflammation: Chronic inflammation of the prostate, such as prostatitis, may increase the risk of prostate cancer.

8. Genetics: Certain inherited genetic mutations, such as those in the BRCA1 and BRCA2 genes, may increase the risk of prostate cancer.

It is important to note that having one or more of these risk factors does not mean that a man will definitely develop prostate cancer, and many men with prostate cancer have no known risk factors.

Additionally, research is ongoing to better understand the causes of prostate cancer and identify additional risk factors.

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