What causes Colon cancer?

['ነዚ ገጽ ስምዓዮ']

መንሽሮ ዓባይ ሳምቡእ እንታይ እዩ ዝገብሮ?

ናይ ኮሎን ካንሰር፡ ብኮሎሬክታል ካንሰር እውን ዝፍለጥ፡ ብሰንኪ ዘይቁጽጽር ናይ ዘይንቡር ዋህዮታት ኣብ ኮሎን ወይ ሬክቱም ዕብየት እዩ ዝመጽእ።

እቲ ልክዕ ጠንቂ ናይ ኮሎን ካንሰር ፍሉጥ ኣይኮነን፣ እንተኾነ ግን ብዙሓት ረቛሒታት ነቲ ሕማም ናይ ምምዕባል ሓደጋ ከዕብይዎ ይኽእሉ እዮም።

እዚ ድማ፦

1. ዕድመ:- እቲ ናይ ዓባይ ሳምቡእ መንሽሮ ናይ ምሓዝ ተኽእሎ ምስ ዕድመ ይዛይድ: መብዛሕትኡ ግዜ ኸኣ ኣብቶም ልዕሊ 50 ዝዕድሚኦም ሰባት ኢዩ ዝረአ።

2. ናይ ስድራ ቤት ታሪኽ:- ናይ ውልቂ ወይ ናይ ስድራ ቤት ታሪኽ ናይ ዓባይ ሳምቡእ ካንሰር ወይ ፖሊፕ ነቲ ሕማም ናይ ምምዕባል ተኽእሎ የዕብዮ።

3. ውርሻዊ ሕማማት:- ከም ፋሚልያል ኣዴኖማቶስ ፖሊፖሲስ (FAP) ከምኡውን ውርሻዊ ፖሊፖሲስ ዘይብሉ ኮሎረክታል ካንሰር (HNPCC) ዝኣመሰለ ውርሻዊ ጂናዊ ሕማማት ነቲ ናይ ዓባይ ሳምቡእ ካንሰር ንኸጋጥም ዘሎ ተኽእሎ ከዛይዶ ይኽእል ኢዩ።

4. ኣነባብራ፦ ብዙሕ ቀይሕን እተቐርጸን ስጋ ምብላዕ፡ ምብዛሕ ክብደት፡ ምትካኽ ሽጋራን ምብዛሕ ኣልኮላዊ መስተን፡ ነቲ ኣብ ጐድኒ መንሽሮ ዓባይ ሳምቡእ ዚርአ ሓደጋ ኼዛይዶ ይኽእል እዩ።

5. ረስኒ ናይ ከስዐ ሕማም:- ከም ናይ ከስዐ ሕማም ወይ ናይ ክሮን ሕማም ዝኣመሰለ ንነዊሕ ግዜ ዝጸንሕ ረስኒ ናይ ከስዐ ሕማም ነቲ ናይ ከስዐ መንሽሮ ሓደጋ ከዕብዮ ይኽእል ኢዩ።

6. ካልኣይ ዓይነት ሽኮርያ፦ ካልኣይ ዓይነት ሽኮርያ ዘለዎም ሰባት፡ ንናይ ዓብዪ ኸብዲ መንሽሮ ኺቃልዑ ይኽእሉ እዮም።

7. ናይ ጨረር ሕክምና:- ኣብ ከስዐ ዝርከብ ካንሰር ንምሕካም ዝግበር ናይ ጨረር ሕክምና ነቲ ናይ ዓባይ ሳምቡእ ካንሰር ንኸጋጥም ዘሎ ተኽእሎ ከዛይዶ ይኽእል ኢዩ።

8. ዓሌት:- ጸለምቲ ኣመሪካውያን ካብ ካልኦት ዓሌታት ንላዕሊ ናይ ዓባይ ሳምቡእ ካንሰር ናይ ምቅላዕ ዕድሎም ልዑል ኢዩ።

ሓደ ወይ ብዙሓት ካብዞም ናይ ሓደጋ ረቛሒታት ምህላዎም ሓደ ሰብ ናይ ኮሎን ካንሰር ክሓምም እዩ ማለት ከምዘይኮነን ናይ ኮሎን ካንሰር ዝሓመሙ ሰባት ድማ ፍሉጥ ዝኾነ ናይ ሓደጋ ረቛሒታት ዘይብሎም ክኾኑ ከምዝኽእሉን ምፍላጥ ኣገዳሲ እዩ።

ስሩዕ መርመራን ኣቐዲምካ ምርካብን መንሽሮ ጐረሮ ንምክልኻል ወይ ድማ ኣብ ሕክምናዊ ምቹእነት ዘለዎ ግዜ ኣብ መጀመርታ ደረጃ ንምልላይ ይሕግዝ።

['መወከሲ']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.

Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.

Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.

Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.

Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.

Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.

Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.

['ናይ ተሓታትነት መግለጺ: ሕክምናዊ']

['እዚ ወብ ሳይት ንትምህርትን ሓበሬታን ጥራይ እዩ ተዋሂቡ: ሕክምናዊ ምኽሪ ወይ ሞያዊ ኣገልግሎት ንምሃብ ተባሂሉ እተዳለወ ድማ ኣይኰነን።']

['እቲ ሓበሬታ ንዝኾነ ናይ ጥዕና ጸገም ወይ ሕማም ንምፍላጥ ወይ ንምሕካም ክውዕል የብሉን፣ እቶም ውልቃዊ ናይ ሕክምና ምኽሪ ዝደልዩ ድማ ምስ ፍቓድ ዘለዎ ሓኪም ክማኸሩ ኣለዎም።']

['እቲ መልሲ ናይቶም ሕቶታት ዝህብ ኔቭራል ኔት፡ ብፍላይ ኣብ ቁጽሪ ዝተሞርኮሰ ሓበሬታ፡ ንኣብነት፡ ብዝሒ ናይቶም ዝተለኽፉ ሰባት ምስ ዝኸውን፡ ኣዝዩ ዘይቅኑዕ ምዃኑ ኣስተብህል።']

['ኩሉ ግዜ ብዛዕባ ናይ ጥዕና ኩነታትካ ምኽሪ ናይ ሓኪምካ ወይ ካልእ ብቑዕ ናይ ጥዕና ኣገልጋሊ ድለ። ኣብዚ መርበብ ሓበሬታ ዘንበብካዮ ነገር ምኽንያት ናይ ሞያ ናይ ሕክምና ምኽሪ ዕሽሽ ኣይትበል። ናይ ሕክምና ህጹጽ ኩነታት ከጋጥመካ ይኽእል እዩ ኢልካ እንተሓሲብካ 911 ደውል ወይ ናብ ዝቐረበ ህጹጽ ክፍሊ ህጹጽ ረድኤት ብቅልጡፍ ኪድ። እዚ መርበብ ሓበሬታ ወይ ኣጠቓቕምኡ ናይ ሓኪምን ሕሙምን ርክብ ኣይፈጥርን። BioMedLib ወይ ሰራሕተኛታቱ ወይ ዝኾነ ኣበርካቲ ናይዚ መርበብ ሓበሬታ እዚ ኣብዚ ዝተዋህበ ሓበሬታ ወይ ኣጠቓቕምኡ ብዝምልከት ዝኾነ ይኹን መግለጺ ወይ ውክልና ኣይህብን እዩ።']

['ናይ መሰል ተሓታትነት']

['ናይ 1998 ዲጂታል ሚሊኒየም ሕጊ መሰል ደራሲ 17 U.S.C. § 512 (the DMCA) ኣብ ኢንተርኔት ዝረአ ዘሎ ትሕዝቶ ብመሰረት ሕጊ መሰል ደራሲ ኣሜሪካ መሰሎም ዝጥሕስ እዩ ኢሎም ንዝኣምኑ ወነንቲ መሰል ደራሲ ይምልከት። ']

['ዝኾነ ትሕዝቶ ወይ ማተርያል ምስ ዌብሳይትና ወይ ኣገልግሎትና ብምትሕሓዝ ዝተዳለወ ንናይ መሰል ዋንነትካ ዝጥሕስ እዩ ኢልካ ብጽቡቕ እምነት እንተኣሚንካ፣ ንስኻ (ወይ ወኪልካ) ነቲ ትሕዝቶ ወይ ማተርያል ክውገድ ወይ ድማ ናብኡ ምእታው ክኽልከል ዝሓትት ምልክታ ክትልእኸልና ትኽእል ኢኻ።']

['እቲ ምልክታ ብጽሑፍ ብኢሜይል ክለኣኽ ኣለዎ (ናይ ኢሜይል ኣድራሻ ንምርካብ ኣብ "Contact" ዝብል ክፋል ተመልከት) ።']

['እቲ DMCA እዚ ዝስዕብ ሓበሬታታት ክካተት ይሓትት፡ (1) መግለጺ ናይቲ ግህሰት ተፈጻምነት ኣለዎ ተባሂሉ ዝሕመ፡ (2) መግለጺ ናይቲ ግህሰት ተፈጻምነት ኣለዎ ተባሂሉ ዝሕመ ትሕዝቶን ነቲ ትሕዝቶ ክንረኽቦ ዘኽእለና እኹል ሓበሬታን (3) ናይ ርክብ ሓበሬታ፡ እንተላይ ኣድራሻኻ፡ ቁጽሪ ተሌፎንካን ናይ ኢመይል ኣድራሻኻን (4) እቲ ትሕዝቶ በቲ ጥርዓን ዝቐርበሉ መገዲ በቲ በዓል መሰል፡ ወይ ወኪሉ ወይ ብዝኾነ ሕጊ ከምዘይፍቀድ ጽቡቕ እምነት ከም ዘሎካ ዝገልጽ መግለጺ፡']

['(5) እቲ ኣብ ምልክታ ዘሎ ሓበሬታ ልክዕ ምዃኑን ነቲ ዝተጣሕሰ መሰል ናይ ምጥባቕ ስልጣን ከምዘለካን ብገበን ናይ ሓሶት ምስክርነት ዝተፈረመ መግለጺኻ፣']

["ከምኡ'ውን (6) ናይ ዋና መሰል ደራሲ ወይ ብስም ዋና መሰል ደራሲ ክሰርሕ ዝተፈቕደሉ ሰብ፡ ኣካላዊ ወይ ኤለክትሮኒካዊ ፊርማ። "]

['እዚ ኩሉ ኣብ ላዕሊ ዝተጠቕሰ ሓበሬታ ዘይምምላእ ነቲ ጥርዓንካ ናይ ምምላስ መስርሕ ክድንጉዮ ይኽእል እዩ።']

['ርክብ']

['ዝኾነ ሕቶ / ሓሳብ ምስ ዝህልወኩም ብኢሜይል ስደዱልና።']

What causes colon cancer?

Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.

The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.

These include:

1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.

2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.

3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.

4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.

5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.

6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.

7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.

8. Race: African Americans have a higher risk of developing colon cancer than other races.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.

Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.

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