What is pathophysiology of Breast cancer?

['Yevelela emẽla eli']

Nye ci lomboloka uvei wo kanser yo vimo?

Oku kuliha eci ci koka uveyi wo kanser yo vimo ci lomboloka apongoloko ka a siatele kovopange kuenda kovisimilo viekalo vi pita vokuenda kuoku kula kuenda oku amamako kuvei wo kanser yo vimo.

Owo u lombolola oku lilongisa eci catiamẽla kekalo kuenda kovimatamata vi tuala koku livokiya kuenda koku lisanduila kuolosinga viocilenda vovipa vionjenje.

Vovina viaco mua kongela ovina viatiamẽla ko DNA, epigenetic kuenda ekalo liofeka okuti vi pondola oku koka uveyi wo kanser.

Vimue pokati kapongoloko a velapo a pita vimo liukãi poku citiwa, mua kongela:

1. Oku pongoloka kuovimatamata viuyali: Oku pongoloka kuovimatamata vimue viuyali ndeci, BRCA1 kuenda BRCA2, ku pondola oku vokiya ohele yoku kuatiwa luvei wo kanser.

Ocitangi caco ci pondola oku piñaliwa ale oku pita lomunu umue vokuenda kuomuenyo waye.

2. Oku tepuluka kuovimatamata viuyali: Ovimatamata viuyali, capiãla enene o estrogénio, vi pondola oku kuatisa koku kula kuoveyi wo kanser.

Nda ukãi o kuete esuka, ale o kuete uvei wo estrogênio, citava okuti o kuatiwa luvei waco.

3. Oku Tulumuka: Oku amamako loku tulama kuetimba ku pondola oku nena uveyi wo kanser poku vetiya oku kula kuolosinga viayo.

4. Ocitumãlo ci kasi ombuto yaco: Ocitumãlo ci kasi ombuto yaco, ci pondola oku vetiya oku kula kuenda oku lisanduila kuvei wo kanser.

5. Oku li sanduila kuovimatamata vikuavo vietimba: Uveyi wo kanser wo vimo u pondola oku lisanduila kolonepa vikuavo vietimba lekuatiso liosonde.

Oku kuata elomboloko liatiamẽla ko kanser yo vimo ci kuete esilivilo koku sanga onjila yoku yi yuvula, oku limbuka lonjanga kuenda oku yi sakula.

['Atosi a Velapo']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Underwood SM: Breast cancer in African American women: nursing essentials. ABNF J. , 17 (1): 3-14.

Paliwal SR, Paliwal R, Agrawal GP, Vyas SP: Liposomal nanomedicine for breast cancer therapy. Nanomedicine (Lond). 2011, 6 (6): 1085-100.

Rauch GM, Adrada BE: Comparison of Breast MR Imaging with Molecular Breast Imaging in Breast Cancer Screening, Diagnosis, Staging, and Treatment Response Evaluation. Magn Reson Imaging Clin N Am. 2018, 26 (2): 273-280.

Wei H, Wang H, Ji Q, Sun J, Tao L, Zhou X: NRBP1 is downregulated in breast cancer and NRBP1 overexpression inhibits cancer cell proliferation through Wnt/β-catenin signaling pathway. Onco Targets Ther. 2015, 8 (): 3721-30.

Eden JA: Human breast cancer stem cells and sex hormones--a narrative review. Menopause. 2010, 17 (4): 801-10.

Schneider BP, Winer EP, Foulkes WD, Garber J, Perou CM, Richardson A, Sledge GW, Carey LA: Triple-negative breast cancer: risk factors to potential targets. Clin Cancer Res. 2008, 14 (24): 8010-8.

['Oku yuvula oku litenga vovitangi:']

['O Web site eyi, ya sandekiwila lika oku longisa omanu kuenda oku va ĩha olonumbi.']

['Nda o yongola oku sakuiwa, sandiliya ondotolo yi kuete uloño woku ci linga.']

['Kũlĩhĩsa okuti, uloño woku konomuisa atambululo apulilo, ka u pondola oku eca atambululo a suapo, ca piãla enene nda etendelo liaco ka lia suilepo.']

['Olonjanja viosi sandiliya ekuatiso liondotolo yove ale liondotolo yikuavo ya loñoloha kueci catiamẽla kocitangi cimue cuhayele. Lalimue eteke ku ka sepule ekuatiso liondotolo ale oku livala koku sandiliya omo liocina cimue wa tanga vo website yilo. Nda o sima okuti o kuete ocitangi cimue cuhayele, vilikiya lonjanga o 911 ale enda lonjanga kosipitali. Ka kuli ukamba umue pokati kondotolo lukuenje wa vela omo lio website yilo ale oku talavaya layo.']

['Oku liyelisa: omoko yoku soneha']

['O Digital Millennium Copyright Act yo 1998, 17 U.S.C. § 512 (o DMCA) yeca epondolo kolonalavayi vi kuete omoko yoku linga eci va sima okuti ovina vi sangiwa vo Internet vi nyõla omoko yavo yi sangiwa vocihandeleko co Estados Unidos. ']

['Nda ove o tava okuti ovina vimue via kapiwa vo Internet ale vovipama vikuavo vi kasi vonumbi yetu vi nyõla omoko yove yoku panga alivulu, ove (ale omunu wa ku nõla) o pondola oku tu tumisa esapulo limue oco tu piñale ovina viaco ale oku vi tateka.']

['Asapulo te a tumiwa loku soneha kuenda vo email (tala vokakasia "Kontato" oco o sange onumbi yo email).']

['DMCA yi kisika okuti esapulo liove lioku lavisa ovihandeleko viovihandeleko viupange mua kongela asapulo akuãimo: (1) elomboluilo liupange u kuete ovihandeleko viupange okuti owo wa lavisiwa; (2) elomboluilo liupange u kuete ovihandeleko viupange kuenda asapulo a tẽla oku ecelela oku sanga upange waco; (3) asapulo oku ku sandiliya, oku kongelamo onumbi yove, etendelo liotelefone kuenda onumbi yo email; (4) esapulo liove okuti ove o kuete ekolelo liwa okuti upange waco ka wa taviwile la muẽliaco ovihandeleko viupange, ale onumiwa yaye, ale oku kuama ovihandeleko; ']

['(5) ukanda umue wa sinaliwa love okuti u lekisa okuti esapulo liaco liocili kuenda o kuete omoko yoku teyuila omoko yove yoku soneha.']

['Kuenda (6) ondimbukiso yocikuata ale yo komputador yomunu ukuete omoko yoku linga upange waco ale yomunu umue o kuete omoko yoku linga upange waco vonduko yomunu ukuete omoko yaco. ']

['Nda kua kongelele ulandu wosi wa tukuiwa ndeti, ci tava okuti o livala poku tetulula ocitangi cove.']

['Oku Sapela']

['Tu tumise o email lapulilo ale ovisimĩlo viove.']

What is pathophysiology of breast cancer?

Pathophysiology of breast cancer refers to the abnormal changes in the normal physiological processes and mechanisms that occur in the development and progression of breast cancer.

It involves the study of the underlying biological and molecular mechanisms that lead to the uncontrolled growth and spread of cancer cells in the breast tissue.

This includes the genetic, epigenetic, and environmental factors that contribute to the initiation, promotion, and progression of breast cancer.

Some of the key pathophysiological changes in breast cancer include:

1. Genetic mutations: Mutations in certain genes, such as BRCA1 and BRCA2, can increase the risk of developing breast cancer.

These mutations can be inherited or acquired during a person's lifetime.

2. Hormonal imbalances: Hormones, particularly estrogen, can play a role in the development and growth of breast cancer.

An imbalance in hormone levels or exposure to excess estrogen can increase the risk of breast cancer.

3. Inflammation: Chronic inflammation in the breast tissue can contribute to the development of breast cancer by promoting the growth and survival of cancer cells.

4. Tumor microenvironment: The environment surrounding the tumor, including the extracellular matrix, immune cells, and blood vessels, can influence the growth and spread of breast cancer.

5. Metastasis: Breast cancer can spread to other parts of the body through the lymphatic system or bloodstream, leading to the formation of secondary tumors in distant organs.

Understanding the pathophysiology of breast cancer is crucial for developing effective prevention, early detection, and treatment strategies.

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Please note the neural net that generates answers to the questions, is specially inaccurate when it comes to numeric content. For example, the number of people diagnosed with a specific disease.

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