How is Alzheimer diagnosed?

Fetí sí ojúewé yìí

Báwo ni wọ́n ṣe máa ń ṣàwárí àrùn Alzheimer?

Wọ́n máa ń lo oríṣiríṣi ọ̀nà láti ṣàwárí àrùn Alzheimer, títí kan àyẹ̀wò ìṣègùn tó jinlẹ̀, àyẹ̀wò ọpọlọ àti àyẹ̀wò ọpọlọ, àyẹ̀wò ọpọlọ, àti ṣíṣe àyẹ̀wò àwọn ohun mìíràn tó lè fa àrùn náà.

1. Ìwádìí nípa ìlera: Dókítà kan á ṣe àyẹ̀wò ara rẹ̀, á sì ṣe àlàyé nípa àìsàn tó ń ṣe é láti mọ bóyá kò sí ohun mìíràn tó lè fa ikú tàbí àìsàn tó ń ṣe ọpọlọ, irú bí àìsàn ti thyroid, àìtó èròjà vitamin, tàbí àrùn ọpọlọ.

2. Ìdánwò ìmòye àti ìmòye ọpọlọ: Àwọn ìdánwò yìí máa ń ṣàyẹ̀wò ìrántí, èdè, bí wọ́n ṣe ń yanjú ìṣòro, àti àwọn iṣẹ́ ìmòye mìíràn láti mọ bí ìmòye wọn ṣe ń bà jẹ́ tó àti láti fi ìyàtọ̀ sáàárín ìrántí tí kò dára tí ọjọ́ orí ń fà àti àìmòye.

3. Àwòrán ọpọlọ: Àwòrán ọpọlọ tí wọ́n ń pè ní magnetic resonance imaging (MRI) tàbí tomography tí wọ́n ń pè ní computed tomography (CT) lè ràn wá lọ́wọ́ láti mọ àwọn ìyípadà tó wà nínú ọpọlọ tó lè fi hàn pé a ní àrùn Alzheimer.

Wọ́n tún lè lo àyẹ̀wò tí wọ́n ń pè ní positron emission tomography (PET) láti mọ bí àwọn èròjà protein kan tó ń fa àrùn Alzheimer ṣe pọ̀ tó.

4. Àyẹ̀wò ẹ̀jẹ̀: Ìwádìí tí wọ́n ṣe lẹ́nu àìpẹ́ yìí fi hàn pé àwọn àyẹ̀wò ẹ̀jẹ̀ kan lè ràn wá lọ́wọ́ láti ṣàwárí àrùn Alzheimer nípa díwọ̀n iye àwọn èròjà protein tàbí àwọn èròjà tó ń fi hàn pé àrùn náà ń ṣe é.

5. Ọ̀nà tí wọ́n gbà ń ṣàwárí àìsàn Alzheimer: Níwọ̀n bí kò ti sí àyẹ̀wò kan ṣoṣo tó dájú tó lè ṣàwárí àìsàn Alzheimer, àyẹ̀wò náà sábà máa ń ní í ṣe pẹ̀lú gbígbé àwọn ohun mìíràn tó lè fa àwọn àmì tó dà bí àìsàn ọpọlọ kúrò.

Ó ṣe pàtàkì láti ṣàkíyèsí pé àìsàn Alzheimer nìkan ni a lè ṣe ìdánilójú tó pé pérépéré lẹ́yìn ikú nípasẹ̀ àyẹ̀wò ti iṣan ọpọlọ.

Àmọ́ ṣá o, àwọn ọ̀nà tí wọ́n ń gbà ṣàwárí àrùn báyìí lè jẹ́ ká mọ bóyá àrùn náà ti wáyé nígbà tí ẹni náà ṣì wà láàyè.

Ó ṣe pàtàkì kí wọ́n tètè ṣàwárí àrùn náà kí wọ́n lè bẹ̀rẹ̀ ìtọ́jú kí wọ́n sì ṣètò ohun tí wọ́n máa ṣe lọ́jọ́ iwájú.

Àwọn ìtumọ̀

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

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[Blood Based Biomarker for Optimization of Early and Differential Diagnosis of Alzheimer's Dementia]. Fortschr Neurol Psychiatr. 2022, 90 (7-08): 326-335.

Kapp MB: Physicians' legal duties regarding the use of genetic tests to predict and diagnose Alzheimer disease. J Leg Med. 2000, 21 (4): 445-75.

Britschgi M, Wyss-Coray T: Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol. 2009, 66 (2): 161-5.

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Imabayashi E, Saitoh Y, Tsukamoto T, Sakata M, Takano H: Combination of Astrogliosis and Phosphorylated Tau for the Preclinical Diagnosis of Alzheimer Disease Using 3-Dimensional Stereotactic Surface Projection Images With 18 F-THK5351. Clin Nucl Med. 2022, 47 (12): 1066-1068.

Martínez A, Lahiri DK, Giacobini E, Greig NH: Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. Curr Alzheimer Res. 2009, 6 (2): 83-5.

Ìyàsímímọ́: ìtọ́jú ìlera

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A ò gbọ́dọ̀ lo ìsọfúnni tó wà nínú ìwé náà láti ṣe àyẹ̀wò tàbí láti wo àìsàn tàbí àìsàn kan wò, àwọn tó bá sì ń wá ìmọ̀ràn nípa ìṣègùn fúnra wọn gbọ́dọ̀ bá dókítà tó ní ìwé àṣẹ sọ̀rọ̀.

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Ìyàsímímọ́: ẹ̀tọ́ ọmọnìyàn

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Ìfọ̀rọ̀wérọ̀

Jọwọ fi imeeli ranṣẹ si wa pẹlu eyikeyi ibeere / imọran.

How is alzheimer diagnosed?

Alzheimer's disease is diagnosed through a combination of methods, including a thorough medical evaluation, cognitive and neuropsychological tests, brain imaging, and the process of elimination of other possible causes.

1. Medical evaluation: A doctor will perform a physical examination and take a detailed medical history to rule out other possible causes of memory loss or cognitive decline, such as thyroid problems, vitamin deficiencies, or brain tumors.

2. Cognitive and neuropsychological tests: These tests assess memory, language, problem-solving, and other cognitive functions to determine the extent of cognitive impairment and to differentiate between normal age-related memory loss and dementia.

3. Brain imaging: Magnetic resonance imaging (MRI) or computed tomography (CT) scans can help identify structural changes in the brain that may indicate Alzheimer's disease.

Positron emission tomography (PET) scans can also be used to measure the levels of certain proteins associated with Alzheimer's disease.

4. Blood tests: Recent research has shown that certain blood tests can help diagnose Alzheimer's disease by measuring the levels of specific proteins or biomarkers associated with the disease.

5. Process of elimination: Since there is no single definitive test for Alzheimer's disease, diagnosis often involves ruling out other possible causes of dementia-like symptoms.

It is important to note that a definitive diagnosis of Alzheimer's disease can only be made after death through an examination of brain tissue.

However, current diagnostic methods can provide a high level of certainty for a clinical diagnosis while the person is still alive.

Early diagnosis is important for starting treatment and planning for the future.

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