What causes Prostate cancer?

Yini ebangela umdlavuza we-prostate?

Imbangela eqondile yomdlavuza we-prostate ayaziwa, kodwa kuye kwatholakala izici eziningana ezingase zandise ingozi yokuthola lesi sifo.

Lezi zihlanganisa:

1. Ubudala: Ingozi yomdlavuza we-prostate iyanda lapho umuntu esemdala, futhi iningi lamacala livela emadodeni angaphezu kweminyaka engu-65.

Umlando womkhaya: Amadoda anamlando womkhaya womdlavuza we-prostate, ikakhulukazi uyise noma umfowabo onalesi sifo, asengozini enkulu.

3. Uhlanga: Amadoda ase-Afrika aseMelika asengozini enkulu yokuthola umdlavuza we-prostate kunabesilisa bezinye izinhlanga.

4. Ukudla: Ukudla okunamafutha amaningi, ikakhulukazi amafutha ezilwane, kungase kwandise ingozi yomdlavuza we-prostate.

5. Ukukhuluphala: Ukukhuluphala ngokweqile noma ukukhuluphala kungandisa ingozi yokuthola umdlavuza we-prostate.

6. Ama-hormone: Amazinga aphakeme e-testosterone namanye ama-hormone abesilisa angase andise ingozi yomdlavuza we-prostate.

7. Ukuvuvukala: Ukuvuvukala okungapheli kwe - prostate, njenge - prostatitis, kungase kwandise ingozi yomdlavuza we - prostate.

8. Izakhi zofuzo: Ukushintshashintsha kwezakhi zofuzo ezithile ezizuzwayo, njengalezo ezenzweni ze - BRCA1 ne - BRCA2, kungase kwandise ingozi yomdlavuza we - prostate.

Kubalulekile ukuphawula ukuthi ukuba nesici esisodwa noma eziningi zalezi zici zobungozi akusho ukuthi indoda nakanjani iyoba nomdlavuza we-prostate, futhi amadoda amaningi anomdlavuza we-prostate awanazo izici zobungozi ezaziwayo.

Ngaphezu kwalokho, ucwaningo luyaqhubeka ukuze kuqondwe kangcono izimbangela zomdlavuza we-prostate futhi kutholakale ezinye izici eziyingozi.

Izikhombo

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Riihimäki M, Thomsen H, Brandt A, Sundquist J, Hemminki K: What do prostate cancer patients die of? Oncologist. 2011, 16 (2): 175-81.

Gilligan T: Social disparities and prostate cancer: mapping the gaps in our knowledge. Cancer Causes Control. 2005, 16 (1): 45-53.

Newschaffer CJ, Otani K, McDonald MK, Penberthy LT: Causes of death in elderly prostate cancer patients and in a comparison nonprostate cancer cohort. J Natl Cancer Inst. 2000, 92 (8): 613-21.

Frydenberg M, Wijesinha S: Diagnosing prostate cancer - what GPs need to know. Aust Fam Physician. 2007, 36 (5): 345-7.

Shimodaira K, Nakashima J, Nakagami Y, Hirasawa Y, Hashimoto T, Satake N, Gondo T, Namiki K, Ohori M, Ohno Y: Prognostic Value of Platelet Counts in Patients with Metastatic Prostate Cancer Treated with Endocrine Therapy. Urol J. 2020, 17 (1): 42-49.

Martínez-Salamanca JI, Ballesteros CM, Carballido Rodríguez J: [Epidemiological fundamentals of clinically localized prostate cancer]. Arch Esp Urol. 2011, 64 (8): 703-10.

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What causes prostate cancer?

The exact cause of prostate cancer is not known, but several factors have been identified that may increase the risk of developing the disease.

These include:

1. Age: The risk of prostate cancer increases with age, with most cases occurring in men over the age of 65.

2. Family history: Men with a family history of prostate cancer, particularly a father or brother with the disease, are at a higher risk.

3. Race: African American men have a higher risk of developing prostate cancer than men of other races.

4. Diet: A diet high in fat, particularly animal fat, may increase the risk of prostate cancer.

5. Obesity: Being overweight or obese may increase the risk of developing prostate cancer.

6. Hormones: High levels of testosterone and other male hormones may increase the risk of prostate cancer.

7. Inflammation: Chronic inflammation of the prostate, such as prostatitis, may increase the risk of prostate cancer.

8. Genetics: Certain inherited genetic mutations, such as those in the BRCA1 and BRCA2 genes, may increase the risk of prostate cancer.

It is important to note that having one or more of these risk factors does not mean that a man will definitely develop prostate cancer, and many men with prostate cancer have no known risk factors.

Additionally, research is ongoing to better understand the causes of prostate cancer and identify additional risk factors.

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