What are the risk factors for Alzheimer?

['Pirengang kaca puniki']

Napi sané dados faktor risiko antuk alzheimer?

Wenten makudang-kudang faktor risiko antuk penyakit Alzheimer, rumasuk:

1. Umur: Risiko ngamolihang penyakit Alzheimer sayan nincap nganutin yusa, antuk katahan anake sané keni penyakit puniki sasampun mayusa 65 warsa.

2. Genetika: madué riwayat kulawarga sané keni penyakit Alzheimer utawi makta gen tertentu, sekadi gen APOE-e4, prasida nincapang risiko nglimbakang penyakit punika.

3. Luka ring sirah: Sejarah trauma sirah sane abot utawi geger otak sane akeh prasida nincapang risiko penyakit Alzheimer.

4. Kesehatan jantung: Kahanan sané ngrusak jantung miwah pembuluh darah, sekadi tekanan darah tinggi, kolesterol tinggi, diabetes, miwah obesitas, prasida nincapang risiko penyakit Alzheimer.

5. Gaya hidup: Ngrokok, nginem alkohol sané akéh, miwah nénten ngamargiang olahraga prasida nincapang baya ngamolihang penyakit Alzheimer.

6. Kurang aktifitas kognitif: Kurang stimulasi mental lan pendidikan rendah prasida nincapang risiko penyakit Alzheimer.

7. Gangguan sare: Gangguan sare, sakadi apnea sare, prasida nincapang baya pinungkan Alzheimer.

8. Faktor psikologis: Depresi, stres, miwah isolasi sosial prasida nincapang risiko penyakit Alzheimer.

Penting pisan mangda uning indik madué asiki utawi akéh faktor risiko puniki nénten ja maarti jadma pacang nglimbakang penyakit Alzheimer, miwah makudang-kudang anak sané nénten madué faktor risiko sané kauningin prasida nglimbakang penyakit.

Nanging, ngresepang faktor risiko puniki prasida ngwantu individu ngambil langkah anggen ngirangin risiko miwah nincapang kesehatan otak.

['Rujukan']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Borenstein AR, Copenhaver CI, Mortimer JA: Early-life risk factors for Alzheimer disease. Alzheimer Dis Assoc Disord. , 20 (1): 63-72.

Pansari K, Gupta A, Thomas P: Alzheimer's disease and vascular factors: facts and theories. Int J Clin Pract. 2002, 56 (3): 197-203.

Kivipelto M, Helkala EL, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Iivonen S, Mannermaa A, Tuomilehto J, Nissinen A, Soininen H: Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med. 2002, 137 (3): 149-55.

Skoog I, Kalaria RN, Breteler MM: Vascular factors and Alzheimer disease. Alzheimer Dis Assoc Disord. , 13 Suppl 3 (): S106-14.

Bidzan L: [Initial symptoms and risk factors in Alzheimer's dementia]. Psychiatr Pol. , 28 (2): 207-19.

Gorelick PB: Risk factors for vascular dementia and Alzheimer disease. Stroke. 2004, 35 (11 Suppl 1): 2620-2.

Kummer BR, Diaz I, Wu X, Aaroe AE, Chen ML, Iadecola C, Kamel H, Navi BB: Associations between cerebrovascular risk factors and parkinson disease. Ann Neurol. 2019, 86 (4): 572-581.

Luchsinger JA, Reitz C, Honig LS, Tang MX, Shea S, Mayeux R: Aggregation of vascular risk factors and risk of incident Alzheimer disease. Neurology. 2005, 65 (4): 545-51.

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What are the risk factors for alzheimer?

There are several risk factors for Alzheimer's disease, including:

1. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

2. Genetics: Having a family history of Alzheimer's disease or carrying certain genes, such as the APOE-e4 gene, can increase the risk of developing the disease.

3. Head injury: A history of severe head trauma or multiple concussions may increase the risk of Alzheimer's disease.

4. Cardiovascular health: Conditions that affect the heart and blood vessels, such as high blood pressure, high cholesterol, diabetes, and obesity, may increase the risk of Alzheimer's disease.

5. Lifestyle factors: Smoking, excessive alcohol consumption, and lack of physical exercise may increase the risk of Alzheimer's disease.

6. Cognitive inactivity: A lack of mental stimulation and low levels of education may increase the risk of Alzheimer's disease.

7. Sleep disorders: Sleep disorders, such as sleep apnea, may increase the risk of Alzheimer's disease.

8. Psychological factors: Depression, stress, and social isolation may increase the risk of Alzheimer's disease.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop Alzheimer's disease, and some people with no known risk factors may still develop the disease.

However, understanding these risk factors can help individuals take steps to reduce their risk and promote brain health.

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