Kanker usus besar, taler kauningin pinaka kanker kolorektal, inggih punika soroh kanker sané kakawitin ring usus besar utawi rektum.
Katahnyané kakawitin antuk tumbuh sané kawastanin polip, sané prasida nglimbak dados kanker saking galah ka galah.
Kanker usus besar inggih punika kanker sané pinih katah kaping tiga ring Amerika Serikat miwah prasida kaobati yéning sampun katemuin ring pangawitnyané.
Faktor risiko antuk kanker usus besar rumasuk yusa, sejarah kulawarga, diet, miwah faktor gaya hidup.
Screening rutin, sekadi kolonoskopi, prasida ngwantu mendeteksi miwah nyegah kanker usus besar.
Paschall AV, Yang D, Lu C, Redd PS, Choi JH, Heaton CM, Lee JR, Nayak-Kapoor A, Liu K: CD133+CD24lo defines a 5-Fluorouracil-resistant colon cancer stem cell-like phenotype. Oncotarget. 2016, 7 (48): 78698-78712.
Liu M, Fu X, Jiang L, Ma J, Zheng X, Wang S, Guo H, Tian T, Nan K, Wang W: Colon cancer cells secreted CXCL11 via RBP-Jκ to facilitated tumour-associated macrophage-induced cancer metastasis. J Cell Mol Med. 2021, 25 (22): 10575-10590.
Wu Q, Wei J, Zhao C, Xiang S, Shi M, Wang Y: Targeting LncRNA EPIC1 to inhibit human colon cancer cell progression. Aging (Albany NY). 2020, 12 (): .
Al-haidari AA, Syk I, Jirström K, Thorlacius H: CCR4 mediates CCL17 (TARC)-induced migration of human colon cancer cells via RhoA/Rho-kinase signaling. Int J Colorectal Dis. 2013, 28 (11): 1479-87.
Zhu Y, Fu F, Wang Z, Qiu F, Deng T, Du B, Zhu Y, Xi X: Polyphyllin VII is a Potential Drug Targeting CD44 Positive Colon Cancer Cells. Curr Cancer Drug Targets. 2022, 22 (5): 426-435.
Jiang L, Qian J, Yang Y, Fan Y: Knockdown of MON1B Exerts Anti-Tumor Effects in Colon Cancer In Vitro. Med Sci Monit. 2018, 24 (): 7710-7718.
Liu X, Jiang WN, Wang JG, Chen H: Colon cancer bears overexpression of OTUB1. Pathol Res Pract. 2014, 210 (11): 770-3.
Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.
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What is colon cancer?
Colon cancer, also known as colorectal cancer, is a type of cancer that begins in the colon or rectum.
It typically starts as a growth called a polyp, which can develop into cancer over time.
Colon cancer is the third most common cancer in the United States and can be treated if caught early.
Risk factors for colon cancer include age, family history, diet, and lifestyle factors.
Regular screening, such as colonoscopies, can help detect and prevent colon cancer.
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