Bushe ubulwele bwa kansa ya kuli bapwapwa bwaba shani?
Icipimo ca malwele ya kansa ya kuli bapwapwa cilosha ku kwaluka kwa fintu fya cifyalilwa ifilenga umuntu alwale kansa ya kuli bapwapwa.
Kansa ya kuli bapwapwa bulwele bwabipa ubwisa pa mulandu wa kuti insandesande sha kuli bapwapwa shilakula no kulekana.
Ishi nsandesande kuti shapanga ifilonda no kusalanganina ku filundwa fimbi ifya mubili, ne ci kuti calenga umuntu ukulwala amalwele yalekanalekana.
Icilenga kansa ya kuli bapwapwa ukulwalika abantu, fintu pamo nga ukufulungana kwa nsandesande, ifyaba mu bwikashi, ne fyo abantu bekala.
Ifyabipa ifingacitika ku DNA ya nsandesande sha mumala kuti fyalenga insandesande ukukula no kulekana ukwabula ukuleka.
Ifi fintu kuti fyaba fya mu cisoolo nelyo fyacitika umuntu nga asambilila, kabili kuti fyacitika nga ca kuti umuntu asangwa na fintu ifilenga kansa pamo nga icushi ca fwaka, radon, asbestos, no mwela wabipa.
Ubulwele bwa kansa ya kuli bapwapwa kuti bwaba mu misango ibili: small cell lung cancer (SCLC) na non-small cell lung cancer (NSCLC).
Ifyabipa ifingacitika kuli ishi kansa sha mumala kuti fyapusana, pantu balipusana mu fyo bafumya ifishili fyabo kabili balasuka ku miti yalekanalekana.
Icilenga kansa ya kuli bapwapwa ukulwalika abantu, fintu ifilenga insandesande sha kansa ukulalwalika abantu bambi, pamo nga insandesande sha bucingo bwa mubili.
Insandesande sha kansa kuti shafulumuka insandesande sha mulwele, ne ci cilenga ukuti shilekula no kusalanganina ukwabula ukulesha.
Na kabili, icilundwa ca kansa icingalenga icilundwa ukulakula kuti calenga icilundwa ukulakula no kusalanganina ku ncende imbi.
Icilenga kansa ya kuli bapwapwa ukuleta amalwele cayanguka kabili abafwailisha pa malwele balabombesha pa kuti beshibe bwino ifyo icilenga.
Li Z, Qian Y, Li W, Liu L, Yu L, Liu X, Wu G, Wang Y, Luo W, Fang F, Liu Y, Song F, Cai Z, Chen W, Huang W: Human Lung Adenocarcinoma-Derived Organoid Models for Drug Screening. iScience. 2020, 23 (8): 101411.
Nurwidya F, Syahruddin E, Yunus F: Pain management in lung cancer. Adv Respir Med. 2016, 84 (6): 331-336.
Khan KA, Kennedy MP, Moore E, Crush L, Prendeville S, Maher MM, Burke L, Henry MT: Radiological characteristics, histological features and clinical outcomes of lung cancer patients with coexistent idiopathic pulmonary fibrosis. Lung. 2015, 193 (1): 71-7.
Paramanantham A, Asfiya R, Das S, McCully G, Srivastava A: Extracellular Vesicle (EVs) Associated Non-Coding RNAs in Lung Cancer and Therapeutics. Int J Mol Sci. 2022, 23 (21): .
Lee D, Kim Y, Chung C: Scientific Validation and Clinical Application of Lung Cancer Organoids. Cells. 2021, 10 (11): .
Mucchietto V, Crespi A, Fasoli F, Clementi F, Gotti C: Neuronal Acetylcholine Nicotinic Receptors as New Targets for Lung Cancer Treatment. Curr Pharm Des. 2016, 22 (14): 2160-9.
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What is pathophysiology of lung cancer?
The pathophysiology of lung cancer refers to the changes in the normal physiological processes and mechanisms that occur in the development and progression of lung cancer.
Lung cancer is a complex disease that arises from the uncontrolled growth and division of abnormal cells in the lungs.
These cells can form tumors and spread to other parts of the body, leading to various symptoms and complications.
The pathophysiology of lung cancer involves several factors, including genetic mutations, environmental factors, and lifestyle choices.
Genetic mutations can occur in the DNA of lung cells, leading to uncontrolled cell growth and division.
These mutations can be inherited or acquired, and they can be caused by exposure to carcinogens, such as tobacco smoke, radon, asbestos, and air pollution.
Lung cancer can be classified into two main types: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC is further divided into three subtypes: adenocarcinoma, squamous cell carcinoma, and large cell carcinoma.
The pathophysiology of these types of lung cancer can differ, as they have different genetic mutations and respond differently to treatment.
The pathophysiology of lung cancer also involves the interaction between cancer cells and the surrounding tissue, including the immune system.
Cancer cells can evade the immune system, allowing them to grow and spread unchecked.
Additionally, the tumor microenvironment can promote tumor growth and metastasis by providing a supportive environment for cancer cells.
The pathophysiology of lung cancer is a complex and dynamic process, and researchers are continuously working to better understand the underlying mechanisms to develop more effective treatments and improve patient outcomes.
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