What causes Colon cancer?

Mba'e piko pe ombohasýva cáncer de colon?

Cáncer de colon, ojekuaáva avei cáncer colorrectal-ramo, oiko okakuaa rupi umi célula anormal colon térã recto-pe.

Ndojeikuaái mba'érepa oikoite cáncer de colon, katu oĩ heta mba'e ikatúva ombohetave ko mba'asy.

Ko'ãva apytépe oĩ:

1. Ary oguerekóva: Pe cáncer de colon ikatu ojehupyty kakuaavévo, hetave jey oiko tapicha oguerekómava 50 ary.

2. Hasykue ogapýpe: Peteĩ tapicha térã ogaygua oguerekóramo cáncer de colon térã pólipo ombohetave riesgo oguerekóvo ko mba'asy.

3. Síndrome hereditario: Oĩ síndrome genético hereditario, ha'eháicha poliposis adenomatosa familiar (PAF) ha cáncer colorrectal ndaha'éiva poliposis hereditario (CCNHN), ikatúva ombohetave cáncer de colon jehupyty.

4. Mba'éichapa ojeiko: Oje'úramo so'o pytã ha so'o oñembosako'íva, ñande rete ituicháramo, ja'úramo petỹ ha ja'úramo hetaiterei alcohol ikatu ñanembohasy cáncer de colon-gui.

5. Enfermedad inflamatoria intestinal: Enfermedad inflamatoria intestinal hi'aréva, ha'eháicha colitis ulcerosa ha Crohn mba'asy, ikatu ombohetave cáncer de colon.

6.- Mba'asy'ypy 2ha: Umi oguerekóva ko mba'asy ikatuve oguereko cáncer de colon.

7. Radioterapia: Radioterapia ambueichagua cáncer abdominal-pe g̃uarã ikatu ombohetave cáncer de colon riesgo.

8. Raza: Umi afroamericano oguereko peteĩ riesgo hetave cáncer de colon-gui ambue raza-kuéra rovake.

Iporã ja'e peteĩ térã hetave ko'ã factor de riesgo rehegua nde'iséi katuete peteĩ tapicha oguerekotaha cáncer de colon, ha oĩ tapicha oguerekóva cáncer de colon ikatu ndoguerekói factor de riesgo ojeikuaáva.

Umi jehecha jey jepi ha ñepohano pya'e ikatu oipytyvõ ojehapejoko hag̃ua colon cáncer térã ojejuhu haguã peteĩ etapa-pe ikatuvehápe oñepohano.

['Jehechapy']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.

Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.

Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.

Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.

Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.

Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.

Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.

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["Ko página web niko ñehekombo'e ha marandu rehegua añónte, ndaha'éi ñeporandu térã ñepytyvõ pohãnohárape."]

["Ko marandu oñeme'ẽva ndojeporúi va'erã ojeikuaa térã oñepohano hag̃ua peteĩ problema de salud térã mba'asy, ha umi tapicha ohekáva consejo médico ha'eñoháme oñe'ẽva'erã peteĩ pohanohára ikatupyrýva ndive."]

["Ejesareko ta'ãngamýi ñandutigua omoheñóiva mbohovái porandukuérape, noĩporãi ojeipapávo papapy rehegua, techapyrã, tapichakuéra hasýva peteĩ mba'asýpe."]

["Akóinte eheka ne pohãnohára térã ambue pohanohára ikatupyrýva ñe'ẽ peteĩ mba'asýpe. Ani araka'eve remboyke térã reha'arõ'ỹ rehekávo ñe'ẽ pohanohára ikatupyrýva ñe'ẽ remoñe'ẽre ko ñanduti rendápe. Reimo'ãramo ikatuha reikotevẽ peteĩ mba'e hasýva, ehenoikuaa 911 térã tereho pya'e tasyópe. Ko ñanduti renda térã ijeporu ndojapói mba'eveichagua pohanohára ha hasýva jokupyty. BioMedLib, imba'apohára térã oimeraẽ tapicha oipytyvõva ko ñanduti rendápe, nomboajéi mba'eve, he'íva térã he'iséva, marandu oĩva ko'ápe térã ijeporu."]

['Copyright: Copyright']

["Pe Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (DMCA) ome'ẽ recurso umi copyright járape ogueroviáva umi mba'e ojehechaukáva Internet-pe opokovaiha iderecho rehe EE.UU. léi jehaiporãmby rehegua rupive. "]

["Rogueroviáramo añetehápe oimeraẽ mba'e térã tembiporu ojepurukuaáva ore ñanduti renda térã tembipurupyahu rupive opyrũha ne derécho rehe, nde (térã ne rembijokuái) ikatu oremondo peteĩ ñemomarandu ojerurévo ojeipe'a hag̃ua upe mba'e térã tembiporu, térã ojejokopa hag̃ua ijeike. "]

['Umi ñemomarandu oñemog̃uahẽva\'erã kuatia rupive, correo electrónico rupive (ojehecháta "Contacto" pe).']

["DMCA ojerure ne ñemomarandu rehe ejaposégui mba'evai ejaposéva rehe toike ko'ã mba'e: (1) tembiapo ojejaposéva rehegua ha'éva mba'evai; (2) jehaipy ha mba'ekuaarã ome'ẽva oréve jehaipyre ha'éva mba'evai ha ome'ẽva oréve pa'ũ rojuhu hag̃ua; (3) ne ñanduti veve, ne rendaite, ne pumbyry papapy ha ne ñanduti veve; (4) ñe'ẽme'ẽ erekóva rejeroviaha pe mba'evai ejaposéva rehe ndojeruréiha mba'evai apohára, imaranduhára térã léi."]

["5. peteî declaración nde rejapóva, remoîva nde réra ha remoîva'erâha nde jurúpe, umi mba'e oîva ñemomarandúpe oîmbaha añetehápe ha rerekoha pokatu remoañete haguâ umi derecho oje'éva nde rehe ojepoko vaiha;"]

["ha (6) peteĩ firma física térã electrónica copyright jára rehegua térã peteĩ tapicha omoneĩva oporoñemomba'e hag̃ua copyright jára rérape. "]

["Ndoikéi ramo opaite ko'ã mba'e ikatu ombohape nde denuncia ñemboguata."]

['Ñemboheraguapy']

["Remba'eporanduséramo térã ereko hag̃ua ne remiandu ehai oréve."]

What causes colon cancer?

Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.

The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.

These include:

1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.

2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.

3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.

4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.

5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.

6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.

7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.

8. Race: African Americans have a higher risk of developing colon cancer than other races.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.

Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.

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