Kansè kolon, ke yo rele tou kansè kolorektal, se yon kansè ki koze pa kwasans san kontwòl nan selil nòmal nan kolon oswa rektòm.
Kòz egzak kansè kolon an pa konnen, men plizyè faktè ka ogmante risk pou devlope maladi a.
Men kèk egzanp:
1. Laj: Risk pou yon moun gen kansè nan kolon ogmante avèk laj, e pifò ka kansè nan kolon rive sou moun ki gen plis pase 50 an.
2. Istwa fanmi: Si yon moun oswa yon fanmi gen kansè nan kolon oswa polip, sa ogmante risk pou yo gen maladi a.
3. Sendwòm eritye: Gen kèk sendwòm jenetik moun eritye, tankou polipoz adenomatosus familial (FAP) ak kansè kolonektal ki pa gen polipoz (HNPCC), ki ka ogmante risk pou yo gen kansè nan kolon.
4. Fason moun viv: Lè yon moun manje vyann wouj ak vyann ki trete anpil, lè l twò gwo, lè l fimen ak lè l bwè twòp alkòl, sa ka fè l gen plis chans pou l gen kansè nan kolon.
5. Maladi enflamatwa nan trip: Maladi enflamatwa nan trip ki dire lontan, tankou maladi ilsè nan kolon ak maladi Crohn, kapab ogmante risk pou gen kansè nan kolon.
6. Dyabèt tip 2: Moun ki gen dyabèt tip 2 gen plis chans pou yo gen kansè nan kolon.
7. Terapi radyasyon: Terapi radyasyon pou lòt kansè nan vant ka ogmante risk pou kansè nan kolon.
8. Ras: Ameriken nwa yo gen plis risk pou yo gen kansè nan kolon pase lòt ras.
Li enpòtan pou note ke gen youn oubyen plis nan faktè risk sa yo pa nesesèman vle di ke yon moun ap devlope kansè nan kolon, e kèk moun ki devlope kansè nan kolon ka pa gen okenn faktè risk li te ye.
Si nou fè tès regilyèman pou nou konnen si nou gen kansè nan kolon e si nou detekte l byen bonè, sa ka ede nou anpeche kansè nan kolon an oswa detekte l byen bonè lè l pi fasil pou nou trete l.
McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.
Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.
Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.
Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.
Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.
Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.
Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.
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['e (6) yon siyati fizik oubyen elektwonik mèt copyright la oubyen yon moun ki otorize pou aji sou non mèt copyright la. ']
['Si ou pa bay tout enfòmasyon ki anwo yo, sa ka fè ke nou pa trete plent ou a byen vit.']
['Kontak']
['Tanpri voye nou yon imèl avèk nenpòt kesyon / sijesyon.']
What causes colon cancer?
Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.
The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.
These include:
1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.
2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.
3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.
4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.
5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.
6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.
7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.
8. Race: African Americans have a higher risk of developing colon cancer than other races.
It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.
Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.
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