Pathophysiology de kansè nan tete refere a chanjman nòmal nan nòmal pwosesis fizyolojik ak mekanis ki rive nan devlopman ak pwogresyon de kansè nan tete.
Li enplike etid la de baz biyolojik ak molekilè mekanis ki mennen a san kontwòl croissance Et pwopagasyon de cellules kansè nan tete tissus.
Sa gen ladan faktè jenetik, epigenetik, ak anviwònman ki kontribye nan kòmansman, pwomosyon, ak pwogresyon kansè nan tete.
Kèk nan chanjman patofizyolojik kle nan kansè nan tete gen ladan:
1. Mutasyon jenetik: Mutasyon nan sèten jèn, tankou BRCA1 ak BRCA2, kapab ogmante risk pou devlope kansè nan tete.
Mutasyon sa yo kapab eritye oubyen akeri pandan lavi yon moun.
2. Hormonal imbalances: Hormones, patikilyèman estwojèn, ka jwe yon wòl nan devlopman ak kwasans kansè nan tete.
Yon move balans nan nivo òmòn yo oswa ekspoze a estwojèn anplis kapab ogmante risk pou kansè nan tete.
3. Enflamasyon: Enflamasyon kwonik nan tisi tete a kapab kontribye nan devlopman kansè nan tete lè li ankouraje kwasans ak siviv selil kansè yo.
4. Mikwo anviwònman timè a: Anviwònman ki antoure timè a, ki gen ladan matris ekstracelular la, selil iminitè yo, ak veso sangen yo, kapab enfliyanse kwasans ak pwopagasyon kansè nan tete.
5. Metastaz: Kansè nan tete kapab gaye nan lòt pati nan kò a atravè sistèm lenfatik la oswa nan san an, sa ki ka lakòz fòmasyon timè segondè nan ògàn ki lwen yo.
Konprann patofizyoloji kansè nan tete enpòtan anpil pou devlope prevansyon efikas, deteksyon bonè, ak estrateji tretman.
Underwood SM: Breast cancer in African American women: nursing essentials. ABNF J. , 17 (1): 3-14.
Paliwal SR, Paliwal R, Agrawal GP, Vyas SP: Liposomal nanomedicine for breast cancer therapy. Nanomedicine (Lond). 2011, 6 (6): 1085-100.
Rauch GM, Adrada BE: Comparison of Breast MR Imaging with Molecular Breast Imaging in Breast Cancer Screening, Diagnosis, Staging, and Treatment Response Evaluation. Magn Reson Imaging Clin N Am. 2018, 26 (2): 273-280.
Wei H, Wang H, Ji Q, Sun J, Tao L, Zhou X: NRBP1 is downregulated in breast cancer and NRBP1 overexpression inhibits cancer cell proliferation through Wnt/β-catenin signaling pathway. Onco Targets Ther. 2015, 8 (): 3721-30.
Eden JA: Human breast cancer stem cells and sex hormones--a narrative review. Menopause. 2010, 17 (4): 801-10.
Schneider BP, Winer EP, Foulkes WD, Garber J, Perou CM, Richardson A, Sledge GW, Carey LA: Triple-negative breast cancer: risk factors to potential targets. Clin Cancer Res. 2008, 14 (24): 8010-8.
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What is pathophysiology of breast cancer?
Pathophysiology of breast cancer refers to the abnormal changes in the normal physiological processes and mechanisms that occur in the development and progression of breast cancer.
It involves the study of the underlying biological and molecular mechanisms that lead to the uncontrolled growth and spread of cancer cells in the breast tissue.
This includes the genetic, epigenetic, and environmental factors that contribute to the initiation, promotion, and progression of breast cancer.
Some of the key pathophysiological changes in breast cancer include:
1. Genetic mutations: Mutations in certain genes, such as BRCA1 and BRCA2, can increase the risk of developing breast cancer.
These mutations can be inherited or acquired during a person's lifetime.
2. Hormonal imbalances: Hormones, particularly estrogen, can play a role in the development and growth of breast cancer.
An imbalance in hormone levels or exposure to excess estrogen can increase the risk of breast cancer.
3. Inflammation: Chronic inflammation in the breast tissue can contribute to the development of breast cancer by promoting the growth and survival of cancer cells.
4. Tumor microenvironment: The environment surrounding the tumor, including the extracellular matrix, immune cells, and blood vessels, can influence the growth and spread of breast cancer.
5. Metastasis: Breast cancer can spread to other parts of the body through the lymphatic system or bloodstream, leading to the formation of secondary tumors in distant organs.
Understanding the pathophysiology of breast cancer is crucial for developing effective prevention, early detection, and treatment strategies.
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