Urticaria, nke a na-akpọkarị akpịrị ịkpọ nkụ, bụ ọrịa akpụkpọ ahụ nke na-eme ka akpịrị na-akpọ nkụ, nke nwere ike ịpụta n'akụkụ ọ bụla nke ahụ.
Ọ pụrụ ịbụ n'ihi ihe dịgasị iche iche, gụnyere mmeghachi omume allergy, ọrịa, ma ọ bụ ọrịa ndị ọzọ.
Ọgwụgwọ a na-agwọ ọrịa urticaria na-adabere n'otú ọrịa ahụ si sie ike na ihe kpatara ya.
Ndị a bụ ụfọdụ ụzọ ndị a na-ejikarị agwọ ọrịa:
1. Antihistamines: Ọgwụ ndị a na-enyere aka belata ọnyá na mbufụt site n'igbochi mmetụta nke histamine, bụ́ kemịkal nke ahụ na-ewepụta n'oge mmeghachi omume allergy.
Ọgwụ ndị na-egbochi ọrịa dị ka diphenhydramine (Benadryl) ma ọ bụ loratadine (Claritin) nwere ike ịdị irè n'ọnọdụ ndị dị nro.
N'ọnọdụ ndị siri ike karị, dọkịta nwere ike inye gị ọgwụ ndị na-egbochi ọrịa ndị siri ike karị.
2. Corticosteroids: N'ọnọdụ ebe ọgwụ antihistamines na-adịghị arụ ọrụ, a pụrụ inye corticosteroids dị ka prednisone iji belata mbufụt ma gbochie usoro ahụ ji alụso ọrịa ọgụ.
A na-ejikarị ọgwụ ndị a eme ihe site n'ọnụ ma nwee ike inye enyemaka ngwa ngwa.
3. Ndị na- egbochi ọrịa: N' ọnọdụ nke urticaria na- adịgide adịgide nke na- adịghị azaghachi ọgwụgwọ ndị ọzọ, a pụrụ inye ọgwụ ndị na- egbochi ọrịa dị ka cyclosporine ma ọ bụ methotrexate iji gbochie usoro ahụ ji alụso ọrịa ọgụ ma belata mbufụt.
4. Omalizumab: Ọgwụ a bụ ọgwụ mgbochi monoclonal a na- agbanye agbanye nke na- elekwasị anya ma na- egbochi immunoglobulin E (IgE), protein nke na- akpata mmeghachi omume allergy.
A na-ejikarị ya eme ihe maka urticaria na-adịghị ala ala nke na-azaghị ọgwụgwọ ndị ọzọ.
5. Zere ihe ndị na-akpata ọrịa urticaria: Ịmata ihe ndị na-akpata ọrịa urticaria na izere ha pụrụ inye aka igbochi ọrịa ndị na-efe efe.
Ihe ndị na-akpatakarị ya bụ nri ụfọdụ, ọgwụ, ahụhụ, okpomọkụ, oyi, ma ọ bụ ìhè anyanwụ.
6. Ihe na-ajụ oyi: Ime ihe na-ajụ oyi n'ebe ahụ ọrịa ahụ metụtara pụrụ inye aka belata ọnyá na mbufụt.
7. Ihe mkpuchi mmiri: A pụrụ iji ihe mkpuchi mmiri mee ihe iji belata ọnya na ibelata mbufụt.
A na-eji ákwà mmiri kechie ebe ahụ ọrịa ahụ metụtara, e mesịakwa, a na-etinye ákwà akọrọ n'elu ya iji jide mmiri.
8. Ọgwụgwọ site n'ìhè: Ikpughe onwe onye n'ìhè ultraviolet pụrụ inye aka igbochi usoro ahụ ji alụso ọrịa ọgụ ma belata mbufụt n'ọnọdụ ụfọdụ nke urticaria na-adịgide adịgide.
Ọ dị mkpa ka ị gakwuru onye na-ahụ maka ahụ ike maka nchoputa na ọgwụgwọ kwesịrị ekwesị nke urticaria.
Ha pụrụ inye aka chọpụta ihe na-akpata ya ma tụọ aro maka usoro ọgwụgwọ kasị mma.
Deleanu D, Nedelea I, Petricau C, Leru P, Dumitrascu D, Muntean A: Clinical impact of omalizumab in refractory chronic urticaria: One centre experience. Exp Ther Med. 2019, 18 (6): 5078-5081.
Grundmann SA, Kiefer S, Luger TA, Brehler R: Delayed pressure urticaria - dapsone heading for first-line therapy? J Dtsch Dermatol Ges. 2011, 9 (11): 908-12.
Staumont-Sallé D, Piette F, Delaporte E: [Etiological diagnosis and treatment of chronic urticaria]. Rev Med Interne. 2003, 24 (1): 34-44.
Akashi R, Ishiguro N, Shimizu S, Kawashima M: Clinical study of the relationship between Helicobacter pylori and chronic urticaria and prurigo chronica multiformis: effectiveness of eradication therapy for Helicobacter pylori. J Dermatol. 2011, 38 (8): 761-6.
Calogiuri G, Nettis E, Mandurino-Mirizzi A, Di Leo E, Macchia L, Foti C, Vacca A, Kounis NG: Omalizumab for the Treatment of Persistent Drug Induced Urticaria Elicited by Thienopyridines: A Case Report. Antiinflamm Antiallergy Agents Med Chem. 2020, 19 (3): 335-339.
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How to treat urticaria?
Urticaria, commonly known as hives, is a skin condition characterized by itchy, raised welts that can appear on any part of the body.
It can be caused by various factors, including allergic reactions, infections, or underlying medical conditions.
Treatment for urticaria depends on the severity of the condition and the underlying cause.
Here are some common treatment options:
1. Antihistamines: These medications help to reduce itching and swelling by blocking the effects of histamine, a chemical released by the body during an allergic reaction.
Over-the-counter antihistamines such as diphenhydramine (Benadryl) or loratadine (Claritin) can be effective in mild cases.
In more severe cases, a doctor may prescribe stronger antihistamines.
2. Corticosteroids: In cases where antihistamines are not effective, corticosteroids such as prednisone may be prescribed to reduce inflammation and suppress the immune system.
These medications are usually taken orally and can provide quick relief.
3. Immunosuppressants: In cases of chronic urticaria that do not respond to other treatments, immunosuppressant drugs such as cyclosporine or methotrexate may be prescribed to suppress the immune system and reduce inflammation.
4. Omalizumab: This medication is an injectable monoclonal antibody that targets and blocks immunoglobulin E (IgE), a protein involved in allergic reactions.
It is typically used for chronic urticaria that does not respond to other treatments.
5. Avoid triggers: Identifying and avoiding triggers that cause urticaria can help prevent outbreaks.
Common triggers include certain foods, medications, insect bites, and exposure to heat, cold, or sunlight.
6. Cold compress: Applying a cold compress to the affected area can help reduce itching and swelling.
7. Wet wraps: Wet wraps can be used to soothe itching and reduce inflammation.
A damp cloth is wrapped around the affected area, and then a dry cloth is placed over it to retain moisture.
8. Phototherapy: Exposure to ultraviolet light can help suppress the immune system and reduce inflammation in some cases of chronic urticaria.
It is important to consult a healthcare professional for proper diagnosis and treatment of urticaria.
They can help determine the underlying cause and recommend the most appropriate treatment plan.
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