Pathophysiology nke ọrịa cancer colon na-ezo aka na usoro na usoro ndị na-eduga na mmepe na ọganihu nke ọrịa cancer colon.
Ọrịa cancer nke afọ, nke a makwaara dị ka ọrịa cancer nke afọ, bụ ụdị ọrịa cancer nke na- amalite na afọ ma ọ bụ rectum, nke bụ akụkụ nke eriri afọ buru ibu.
Ọ na- amalitekarị dị ka ihe a na- akpọ polyp, nke pụrụ ịghọ ọrịa cancer ka oge na- aga.
Pathophysiology nke ọrịa cancer colon na-agụnye ọtụtụ ihe, gụnyere mgbanwe mkpụrụ ndụ ihe nketa, mbufụt, na ihe ndị metụtara gburugburu ebe obibi.
Mgbanwe mkpụrụ ndụ ihe nketa pụrụ ime na DNA nke mkpụrụ ndụ afọ, na-eduga n'uto na nkewa nke mkpụrụ ndụ n'enweghị nchịkwa.
Mgbanwe ndị a pụrụ ịbụ nke a ketara eketa ma ọ bụ nke a nwetara, ha pụkwara imetụta mkpụrụ ndụ ihe nketa dị iche iche ndị na-ekere òkè n'uto, nkewa, na nrụzi nke mkpụrụ ndụ.
Ọrịa ọgbụgba nke na-arịa eriri afọ, bụ́ nke ọrịa ndị dị ka ọrịa ọgbụgba nke eriri afọ pụrụ ịkpata, pụkwara ime ka e nwekwuo ihe ize ndụ nke ịrịa ọrịa cancer nke eriri afọ.
Ọrịa na-adịghị ala ala pụrụ ịkpata ntọhapụ nke ọgwụ ndị na-eme ka mkpụrụ ndụ na-eto ma na-ekewa, bụ́ nke pụrụ iduga n'inwe ọrịa cancer.
Ihe ndị na-eme gburugburu ebe obibi, dị ka nri a na-eri, otú e si ebi ndụ, na otú e si eji ọgwụ ụfọdụ eme ihe, pụkwara ime ka e nwee ọrịa cancer afọ.
Dị ka ihe atụ, a na-ejikọta nri e ji anụ na-acha ọbara ọbara na nke e ji ihe ndị e ji emepụta mee na-abawanye ihe ize ndụ nke ịrịa ọrịa cancer afọ.
Ihe ndị ọzọ, dị ka ibu oké ibu, ịṅụ sịga, na ịghara imega ahụ́, pụkwara ime ka ihe ize ndụ ahụ dịkwuo elu.
Ozugbo ọrịa cancer nke afọ buru ibu bilitere, ọ pụrụ ịga n'ihu n'ọtụtụ ọkwa, site n'ọrịa cancer nke dị n'oge na-ejedebe n'afọ buru ibu ruo n'ọkwa ndị ka elu ebe ọrịa cancer agbasawo n'akụkụ ndị ọzọ nke ahụ.
Mkpụrụ ndụ kansa pụrụ ịwakpo akwara na akụkụ ahụ ndị dị nso, ọ pụkwara ịgbasa site n'usoro lymphatic ma ọ bụ ọbara gaa n'ebe ndị dị anya, dị ka imeju ma ọ bụ akpa ume.
Ọgwụgwọ maka ọrịa cancer colon na-agụnyekarị ịwa ahụ, ọgwụgwọ kemotherapy, na ọgwụgwọ ụzarị ọkụ, na-adabere n'ọkwa na ebe ọrịa cancer dị.
Nchọpụta na ọgwụgwọ n'oge bụ isi ihe na-eme ka nsonaazụ dịkwuo mma, ebe ọ bụ na a na-agwọkarị ọrịa kansa afọ ma ọ bụrụ na a chọpụta ya n'oge.
Nnyocha a na-eme mgbe nile, dị ka colonoscopy, pụrụ inye aka ịchọpụta ọrịa cancer nke eriri afọ n'oge mbụ ya, mgbe a pụrụ ịgwọ ya nke ọma.
Vidal-Vanaclocha F: The liver prometastatic reaction of cancer patients: implications for microenvironment-dependent colon cancer gene regulation. Cancer Microenviron. 2011, 4 (2): 163-80.
Yagi T, Kubota E, Koyama H, Tanaka T, Kataoka H, Imaeda K, Joh T: Glucagon promotes colon cancer cell growth via regulating AMPK and MAPK pathways. Oncotarget. 2018, 9 (12): 10650-10664.
Sharma SH, Thulasingam S, Nagarajan S: Terpenoids as anti-colon cancer agents - A comprehensive review on its mechanistic perspectives. Eur J Pharmacol. 2017, 795 (): 169-178.
Keshk WA, Zineldeen DH, Wasfy RE, El-Khadrawy OH: Fatty acid synthase/oxidized low-density lipoprotein as metabolic oncogenes linking obesity to colon cancer via NF-kappa B in Egyptians. Med Oncol. 2014, 31 (10): 192.
Dongfeng D, An C, Shujia P, Jikai Y, Tao Y, Rui D, Kai T, Yafeng C, Jianguo L, Xilin D: Explanation of colon cancer pathophysiology through analyzing the disrupted homeostasis of bile acids. Afr Health Sci. 2014, 14 (4): 925-8.
Tammali R, Ramana KV, Srivastava SK: Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells. Cancer Lett. 2007, 252 (2): 299-306.
Nkwupụta: ọgwụgwọ
A na-enye weebụsaịtị a maka ebumnuche agụmakwụkwọ na ozi naanị ma ọ bụghị inye ndụmọdụ ahụike ma ọ bụ ọrụ ọkachamara.
E kwesịghị iji ihe ọmụma e nyere mee ihe maka ịchọpụta ma ọ bụ ịgwọ nsogbu ahụ ike ma ọ bụ ọrịa, ndị na-achọ ndụmọdụ ahụike onwe ha kwesịrị ịgakwuru dọkịta nwere ikike.
Biko rịba ama na netwọkụ akwara nke na-emepụta azịza nye ajụjụ ndị ahụ, bụ ihe na-ezighi ezi mgbe ọ na-abịa na ọnụọgụ ọnụọgụ. Dịka ọmụmaatụ, ọnụọgụ ndị mmadụ chọpụtara na ọrịa akọwapụtara.
Na-achọkarị ndụmọdụ nke dọkịta gị ma ọ bụ onye na-ahụ maka ahụike ọzọ ruru eru banyere ọnọdụ ahụike. Elegharala ndụmọdụ ahụike ọkachamara anya ma ọ bụ na-egbu oge n'ịchọ ya n'ihi ihe ị gụrụ na weebụsaịtị a. Ọ bụrụ na i chere na ị nwere ike ịnweta mberede ahụike, kpọọ 911 ma ọ bụ gaa n'ọnụ ụlọ mberede kacha nso ozugbo. Enweghị mmekọrịta dọkịta na onye ọrịa na-emepụta site na weebụsaịtị a ma ọ bụ ojiji ya. Ma BioMedLib ma ndị ọrụ ya, ma onye ọ bụla na-enye aka na weebụsaịtị a, anaghị eme nkwupụta ọ bụla, kwupụta ma ọ bụ kwupụta, gbasara ozi enyere ebe a ma ọ bụ ojiji ya.
Nkwupụta: ikike nwebisiinka
Digital Millennium Copyright Act nke 1998, 17 U.S.C. § 512 (DMCA) na-enye ohere maka ndị nwe ikike nwebisiinka nke kwenyere na ihe na-apụta na ịntanetị na-emebi ikike ha n'okpuru iwu ikike nwebisiinka US.
Ọ bụrụ na ị kwenyere n'ezi okwukwe na ọdịnaya ma ọ bụ ihe ọ bụla enyere na njikọ nke weebụsaịtị anyị ma ọ bụ ọrụ na-emebi ikike nwebisiinka gị, gị (ma ọ bụ onye nnọchi anya gị) nwere ike iziga anyị ọkwa na-arịọ ka ewepụ ọdịnaya ma ọ bụ ihe, ma ọ bụ gbochie ịnweta ya.
A ghaghị izipu ọkwa n'akwụkwọ site na email (lee ngalaba "Kọntaktị" maka adreesị email) .
DMCA na-achọ ka ọkwa gị banyere mmebi iwu nwebisiinka na-ekwu na ọ gụnyere ozi ndị a: (1) nkọwa nke ọrụ nwebisiinka nke bụ isiokwu nke mmebi iwu a na-ekwu; (2) nkọwa nke ihe a na-ekwu na ọ na-emebi iwu na ozi zuru ezu iji mee ka anyị chọta ọdịnaya ahụ; (3) ozi kọntaktị maka gị, gụnyere adreesị gị, nọmba ekwentị na adreesị email; (4) nkwupụta site n'aka gị na ị nwere ezi okwukwe na ọdịnaya n'ụzọ a na-eme mkpesa na ọ bụghị ikike site n'aka onye nwe ikike, ma ọ bụ onye nnọchi anya ya, ma ọ bụ site na ọrụ iwu ọ bụla;
(5) nkwupụta site n'aka gị, nke ị bịanyere aka na ya n'okpuru ntaramahụhụ nke ịgba akaebe ụgha, na ozi dị na ọkwa ahụ ziri ezi na na ị nwere ikike iji mezuo ikike nwebisiinka nke a na-ekwu na emebi;
na (6) mbinye aka nkịtị ma ọ bụ nke elektrọnik nke onye nwe ikike ma ọ bụ onye e nyere ikike ime ihe n'aha onye nwe ikike.
Ọ bụrụ na i tinyeghị ozi niile dị n'elu, ọ nwere ike ime ka a na-egbu oge n'ịhazi mkpesa gị.
Mkparịta ụka
Biko zitere anyị email na ajụjụ ọ bụla / aro.
What is pathophysiology of colon cancer?
The pathophysiology of colon cancer refers to the underlying mechanisms and processes that lead to the development and progression of colon cancer.
Colon cancer, also known as colorectal cancer, is a type of cancer that begins in the colon or rectum, which are parts of the large intestine.
It typically starts as a growth called a polyp, which can develop into cancer over time.
The pathophysiology of colon cancer involves several factors, including genetic mutations, inflammation, and environmental factors.
Genetic mutations can occur in the DNA of colon cells, leading to uncontrolled cell growth and division.
These mutations can be inherited or acquired, and they can affect various genes involved in cell growth, division, and repair.
Inflammation in the colon, which can be caused by conditions such as inflammatory bowel disease, can also increase the risk of colon cancer.
Chronic inflammation can lead to the release of chemicals that promote cell growth and division, potentially leading to the development of cancer.
Environmental factors, such as diet, lifestyle, and exposure to certain chemicals, can also contribute to the development of colon cancer.
A diet high in red and processed meats, for example, has been linked to an increased risk of colon cancer.
Other factors, such as obesity, smoking, and lack of physical activity, can also increase the risk.
Once colon cancer develops, it can progress through several stages, from early-stage cancer that is confined to the colon to more advanced stages where the cancer has spread to other parts of the body.
The cancer cells can invade nearby tissues and organs, and may also spread through the lymphatic system or bloodstream to distant sites, such as the liver or lungs.
Treatment for colon cancer typically involves a combination of surgery, chemotherapy, and radiation therapy, depending on the stage and location of the cancer.
Early detection and treatment are key to improving outcomes, as colon cancer is often curable when caught in its early stages.
Regular screening, such as colonoscopy, can help detect colon cancer at its earliest stages, when it is most treatable.
Disclaimer: medical
This web site is provided for educational and informational purposes only and does not constitute providing medical advice or professional services.
The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician.
Please note the neural net that generates answers to the questions, is specially inaccurate when it comes to numeric content. For example, the number of people diagnosed with a specific disease.
Always seek the advice of your doctor or other qualified health provider regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. If you think you may have a medical emergency, call 911 or go to the nearest emergency room immediately. No physician-patient relationship is created by this web site or its use. Neither BioMedLib nor its employees, nor any contributor to this web site, makes any representations, express or implied, with respect to the information provided herein or to its use.
Disclaimer: copyright
The Digital Millennium Copyright Act of 1998, 17 U.S.C. § 512 (the “DMCA”) provides recourse for copyright owners who believe that material appearing on the Internet infringes their rights under U.S. copyright law. If you believe in good faith that any content or material made available in connection with our website or services infringes your copyright, you (or your agent) may send us a notice requesting that the content or material be removed, or access to it blocked. Notices must be sent in writing by email (see 'Contact' section for email address) . The DMCA requires that your notice of alleged copyright infringement include the following information: (1) description of the copyrighted work that is the subject of claimed infringement; (2) description of the alleged infringing content and information sufficient to permit us to locate the content; (3) contact information for you, including your address, telephone number and email address; (4) a statement by you that you have a good faith belief that the content in the manner complained of is not authorized by the copyright owner, or its agent, or by the operation of any law; (5) a statement by you, signed under penalty of perjury, that the information in the notification is accurate and that you have the authority to enforce the copyrights that are claimed to be infringed; and (6) a physical or electronic signature of the copyright owner or a person authorized to act on the copyright owner’s behalf. Failure to include all of the above information may result in the delay of the processing of your complaint.
