How is Prostate cancer diagnosed?

['Welisi hɔɔlʋʋ kʋnɛ']

Ɛzɩma patɩlɩɣ ɛyʋ weyi ɛwɛnɩ cancer kʋdɔŋ yɔ?

Palakɩ kʋdɔmɩŋ ɛnɩ nɛ nʋmɔŋ ndɩ ndɩ.

1. (a) Tɩŋgbaŋaɣ ŋga patɩŋɩɣnɩ kɔ-yɔɔ nɛ panaɣ ɛyʋ yɔ: Ðɔkɔtɔ nɔɔyʋ kpakɩɣ e-niye nɖɩ ɛpamnɩ ñɩɣyʋʋ kɩsɛɛmʋʋ yɔ nɛ ɛsʋʋ ɛ-hʋyʋʋ taa se ɛna se kʋdɔŋ nakʋyʋ fɛyɩ yaa we.

2. Calɩm taa hosi lɩzʋʋ tʊmɩyɛ (ADN): Calɩm taa hosi lɩzʋʋ tʊmɩyɛ nɖɩ ɖɩlɩzɩɣ calɩm taa hosi lɩzʋʋ tʊmɩyɛ nɖɩ payaɣ se ADN yɔ.

Ye ɛyʋ ɛwɛnɩ calɩm taa calɩm kiɖe nɖɩ payaɣ se PSA yɔ, pɩpɩzɩɣ nɛ pɩwɩlɩ se ɛwɛnɩ cancer.

3. (a) Transrectal ultrasound (TRUS): Palakɩ-kʋ nɛ ñɩɣyʋʋ cikpeluu nakʋyʋ nɛ pasʋʋ ɛyʋ lotu taa. (b) Palakɩ-kʋ nɛ ñɩɣyʋʋ cikpeluu nakʋyʋ nɛ pasʋʋ ɛyʋ lotu taa.

Pɩpɩzɩɣ pɩsɩnɩ-ɩ nɛ ɛna se kʋdɔŋ nakʋyʋ kpa-ɩ yaa kɩtɩkpa-ɩ.

4. (a) Tɩŋ hatʋ: Palakɩ-ɩ tʊmɩyɛ nɛ palɩzɩɣ tɔnʋʋ cikpeluu nakʋyʋ nɛ pana se kʋdɔŋ piye naɖɩyɛ fɛyɩ kɩ-taa yaa we? (b) Nɛ ɛzɩma palakɩ-ɖɩ?

Nʋmɔʋ ŋgʋ kɩ-yɔɔ ɖeke patɩŋɩɣna nɛ panaɣ ɛyʋ weyi ɛwɛnɩ cancer kʋdɔŋ yɔ.

5. (a) Tɩŋnɩ menziini ŋgʋ payaɣ se IRM yɔ kɩ-yɔɔ nɛ ŋtɩlɩ kʋdɔŋ piye nɖɩ ɖɩ-yɔɔ ŋwɛɛ yɔ: (b) Tɩŋnɩ menziini ŋgʋ payaɣ se IRM yɔ kɩ-yɔɔ nɛ ŋtɩlɩ kʋdɔŋ piye nɖɩ ɖɩ-yɔɔ ŋwɛɛ yɔ.

6. (a) Tɩŋ pee wena calɩm hɔɔlɩŋ cikpeŋ kpɛndɩɣ nɛ pɩlakɩ yɔ: Fɛɖʋ nɔɔyʋ pɩzɩɣ nɛ ɛtɩŋnɩ calɩm hɔɔlɩŋ cikpeŋ kpɛndʋʋ yɔɔ nɛ ɛna se kʋdɔŋ ŋgʋ kɩkɩlɩɣ cɛyʋʋ yaa kɩtɩkɩlɩɣ cɛyʋʋ nɛ pɩsa nɛ ɛpɩzɩ nɛ ɛwaa-kʋ.

7. (a) Tɩŋ hatʋ: Papɩzɩɣ nɛ patɩŋnɩ hatʋ yɔɔ nɛ pana se kʋdɔŋ ŋgʋ kɩtalɩ ɛyʋ mɔɔ na.

8. (a) Tomografi (tomographie): Papɩzɩɣ nɛ patɩŋnɩ kʋdɔŋ ŋgʋ kɩ-yɔɔ nɛ pana se kɩtalɩ tomnaɣ hɔɔlɩŋ lɛɛŋ taa na.

Pɩcɛyaa se ɖɩtɩlɩ se pɩtɩkɛ abalaa mba pa-taa PSA kʋdɔŋ kpawa yɔ yaa mba DRE ɛɛlɩzɩɣ-wɛ camɩyɛ yɔ, pa-tɩŋa pɛwɛnɩ calɩm taa kʋdɔŋ ŋgʋ.

Pʋ-yɔɔ lɛ, pɩcɛyaa se pañɩnɩ tomnaɣ hɔɔlɩŋ nɩɩyɩ nɛ pana se kʋdɔŋ piye nɖɩ ɖɩkɛ toovenim na.

Pɩtasɩ lɛ, pʋcɔ nɛ pakpaɣ lɩmaɣza se palakɩ-ɩ kɔyɛ nɖɩ lɛ, pɩwɛɛ se pamaɣzɩ ɖɔɖɔ mbʋ pɩlɩɣ kɔyɛ nɖɩ ɖɩ-taa yɔ pɩ-yɔɔ, nɛ pana ɖɔɖɔ mbʋ pɩpɩzɩɣ nɛ pɩkɔnɩ-ɩ kʋdɔŋ ŋgʋ yɔ.

['Takayɩhatʋ ndʋ tɩtamsɩna \\ yɔ']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

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Marenco J, Kasivisvanathan V, Emberton M: New standards in prostate biopsy. Arch Esp Urol. 2019, 72 (2): 142-149.

Moradi M, Mousavi P, Abolmaesumi P: Computer-aided diagnosis of prostate cancer with emphasis on ultrasound-based approaches: a review. Ultrasound Med Biol. 2007, 33 (7): 1010-28.

Cuperlovic-Culf M, Belacel N, Davey M, Ouellette RJ: Multi-gene biomarker panel for reference free prostate cancer diagnosis: determination and independent validation. Biomarkers. 2010, 15 (8): 693-706.

McGrath SE, Michael A, Morgan R, Pandha H: EN2: a novel prostate cancer biomarker. Biomark Med. 2013, 7 (6): 893-901.

An Y, Chang W, Wang W, Wu H, Pu K, Wu A, Qin Z, Tao Y, Yue Z, Wang P, Wang Z: A novel tetrapeptide fluorescence sensor for early diagnosis of prostate cancer based on imaging Zn2+ in healthy versus cancerous cells. J Adv Res. 2020, 24 (): 363-370.

[Consensus of Chinese experts on the application of molecular imaging targeting prostate specific membrane antigen in prostate cancer patients]. Zhonghua Wai Ke Za Zhi. 2018, 56 (2): 91-94.

Zhong WD, He HC, Bi XC, Ou RB, Jiang SA, Liu LS: cDNA macroarray for analysis of gene expression profiles in prostate cancer. Chin Med J (Engl). 2006, 119 (7): 570-3.

['Tɔm ndʋ tɩ-yɔɔ ɖitisiɣ yɔ: ɖɔkɔtɔ']

['Ye ŋwobi intɛrnɛɛtɩ lone ɖɩnɛ ɖɩ-yɔɔ yɔ, ŋpɩzɩɣ nɛ ŋkpɛlɩkɩ tɔm sakɩyɛ ɖɩ-yɔɔ.']

['Pɩtɩpɔzɩ se patɩŋnɩ tɔm ndʋ pama takayaɣ kanɛ ka-taa yɔ tɩ-yɔɔ nɛ pañɩnɩ kʋdɔŋ nakʋyʋ yaa pawaa-kʋ.']

['Tɩlɩ camɩyɛ se ordinatɛɛrɩ yɔɔ tɔm ndʋ pɔpɔzʋʋ yɔ, tɩ-yɔɔ cosuu wɛ kaɖɛ, kɔzɩ kɔzɩ alɩwaatʋ ndʋ tɩ-taa pɔpɔzʋʋ tɔm natʋyʋ nɛ tɩ-taa tɔm pee tɩɖɔɔ yɔ.']

['Paa ɛzɩmtaa lɛ, pɔzɩ lɔŋ tasʋʋ fɛɖʋ weyi ɛsɩm ñɔ-yɔɔ tɔm sakɩyɛ yɔ nɛ ɛyɔɔdɩ-ŋ kʋdɔŋ ŋgʋ ŋwɛna yɔ kɩ-tɔm. Taayele nɛ lɔŋ tasʋʋ mbʋ fɛɖʋ ɛnʋ ɛha-ŋ yɔ, pɩɖɛɛ ñɔ-yɔɔ yaa ŋyele-pʋ ñɩnʋʋ mbʋ pʋyɔɔ yɔ ŋkalɩ tɔm natʋyʋ intɛrnɛɛtɩ lone ɖɩnɛ ɖɩ-yɔɔ. Ye ŋmaɣzɩɣ se pɩwɩɣ-ŋ yɔ, yaa ɛyaa 911 yaa ŋwolo ɖɔkɔtɔ ŋgʋ kɩñɔtɩnɩ-ŋ yɔ kɩ-taa kpaagbaa.']

['Takayɩhatʋ ndʋ tɩtamsɩna \\ Paɣtʋ \\ yɔ']

['Digital Millennium Copyright Act 1998 ñɩŋgʋ, 17 U.S.C. § 512 (DMCA) haɣ waɖɛ mba pɛwɛnɩ waɖɛ se pala tʋmɩyɛ intɛrnɛɛtɩ yɔɔ yɔ se pala mbʋ pɩkaɖɩɣnɩ waɖɛ nɖɩ pɛwɛna Etaazuunii ɛjaɖɛ taa yɔ.']

['Ye ŋmaɣzɩɣ se tɔm natʋyʋ yaa wonuu nakʋyʋ yɔɔ pama tɔm intɛrnɛɛtɩ lone ɖɩnɛ ɖɩ-yɔɔ yaa intɛrnɛɛtɩ lone ɖɩnɛ ɖɩ-yɔɔ nɛ pɩkaɖɩɣnɩ ña-paɣtʋ yɔ, ña-maɣmaɣ yaa weyi ɛsɩɣ-ŋ tʋmɩyɛ yɔ, ŋpɩzɩɣ nɛ ŋtiyini-ɖʋ takayaɣ nɛ ŋpɔzɩ se ɖɩlɩzɩ tɔm ndʋ yaa wonuu ŋgʋ yaa ɖitaayele nɛ nɔɔyʋ tɩlɩ-kʋ.']

['Pɩwɛɛ se pama takayaɣ nɛ petiyini ordinatɛɛrɩ yɔɔ.']

['DMCA paɣtʋ pɔzʋʋ se ye ŋnawa se nɔɔyʋ tɩma takayaɣ nakɛyɛ yɔ, ŋma tɔm tʋnɛ: (1) takayaɣ ŋga ŋnawa se nɔɔyʋ tɩma-kɛ yɔ kɔ-yɔɔ tɔm; (2) takayaɣ ŋga kɔ-yɔɔ pamawa se nɔɔyʋ tɩma takayaɣ nakɛyɛ yɔ kɔ-yɔɔ tɔm nɛ tɔm ndʋ tɩsɩɣnɩ-ɖʋ se ɖɩtɩlɩ ɖenɖe ŋnaɣ takayaɣ ŋga yɔ; (3) ña-hɩɖɛ, kaŋgalaafu mayaɣ nɛ intɛrnɛɛtɩ mayaɣ; (4) ŋyɔɔdɩ kpayɩ se ŋwɛnɩ tisuu se takayaɣ ŋga ŋnawa se nɔɔyʋ tɩma-kɛ yɔ, pɩtɩkɛ weyi ɛtɩnɩ takayaɣ ŋga yɔ ɛ-maɣmaɣ ɛlɩzɩnɩ-kɛ, yaa ɛ-tʋmlaɖʋ nɔɔyʋ lɩzɩnɩ-kɛ, yaa se paɣtʋ natʋyʋ ɛɛhaɣ nʋmɔʋ se palabɩnɩ-kɛ tʋmɩyɛ.']

['(5) Ye ŋlabɩ mbʋ yɔ, ŋpɩzɩɣ nɛ ŋcɛtɩnɩ ñɔ-tɔm yɔɔ nɛ ŋyɔɔdɩ se tɔm ndʋ pama takayaɣ ŋga ka-taa yɔ tɩkɛ toovenim nɛ ŋwɛnɩ waɖɛ se ŋlʋ nɛ ŋwa mba payʋsʋʋ se pɛwɛɛkɩ ña-takayaɣ yɔ.']

['Nɛ (6) ye nɔɔyʋ ɛtɩnɩ takayaɣ nakɛyɛ yɔɔ tɔm yɔ, pɩwɛɛ se ɛñɩɣ nesi takayaɣ ŋga kɔ-yɔɔ.']

['Ye patɩyɔɔdɩ tɔm ndʋ tɩ-tɩŋa yɔ, pɩpɩzɩɣ nɛ pɩkɔnɩ tɔm hʋʋ kaɖɛ.']

['Ɛyʋ weyi ŋkatɩɣ yɔ']

['Ye ŋwɛnɩ tɔm natʋyʋ yaa ŋñɩnɩɣ se ŋtasɩ tɔm natʋyʋ yɔ, ɖitendi-ŋ ma-ɖʋ takayaɣ.']

How is prostate cancer diagnosed?

Prostate cancer is diagnosed through a combination of tests and procedures, which may include:

1. Digital Rectal Exam (DRE): A doctor inserts a gloved, lubricated finger into the rectum to feel the prostate for any abnormalities.

2. Prostate-Specific Antigen (PSA) Test: This is a blood test that measures the level of PSA, a protein produced by the prostate gland.

Elevated PSA levels may indicate the presence of prostate cancer.

3. Transrectal Ultrasound (TRUS): A small probe is inserted into the rectum to create an image of the prostate using sound waves.

This can help identify any abnormalities in the prostate gland.

4. Biopsy: A small sample of prostate tissue is removed and examined under a microscope for the presence of cancer cells.

This is the only definitive way to diagnose prostate cancer.

5. Magnetic Resonance Imaging (MRI): An MRI scan of the prostate can help identify any abnormalities and guide the biopsy procedure.

6. Genomic Testing: Some doctors may use genomic tests to help determine the aggressiveness of the cancer and guide treatment decisions.

7. Bone Scan: A bone scan may be performed to check if the cancer has spread to the bones.

8. Computed Tomography (CT) Scan: A CT scan may be used to check if the cancer has spread to other organs or tissues.

It is important to note that not all men with elevated PSA levels or abnormal DRE results will have prostate cancer, and not all prostate cancers will cause elevated PSA levels.

Therefore, a biopsy is necessary to confirm the diagnosis.

Additionally, the decision to undergo a biopsy is made after considering the results of these tests and the individual's risk factors and preferences.

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