What causes Colon cancer?

['Welisi hɔɔlʋʋ kʋnɛ']

Ɛbɛ pɩzɩɣ piyele nɛ ɛyʋ kʋdɔŋ ŋgʋ kɩkpa-ɩ?

Pɩkɛ kʊdɔŋ ŋgʊ kɩlɩna calɩm hosi nzɩ sɩfɛyɩ ɖoŋ yɔ sɩ-tɛ.

Ɛlɛ, wɛtʋ ndɩ ndɩ pɩzɩɣ tiyele nɛ kʋdɔŋ ŋgʋ kɩkpa-ŋ ɖoŋ.

Pa-taa nabɛyɛ yɔ:

1. Akpadɩyɩtʋ: Ɛyaa mba pasʋtʋyaa yɔ, mba kɩlɩɣ-wɛ cɛyʋʋ se pɛwɛɛnɩ kʋdɔŋ ŋgʋ.

2. Ye hɔʋ nakʋyʋ taa ñɩma ɩkatɩ kʋdɔŋ ŋgʋ yɔ: Ye ɛyʋ nɔɔyʋ yaa hɔʋ nakʋyʋ taa ñɩma ɩkatɩ kʋdɔŋ ŋgʋ yɔ, pɩpɩzɩɣ nɛ pɩkpazɩ-ɩ ɖoŋ.

Kʋdɔmɩŋ weyi ɩɖɛɣnɩ ɛyaa yɔ: Kʋdɔmɩŋ nɩɩyɩ pɩzɩɣ nɛ ɩɖɛɛnɩ ɛyaa ɖɔɖɔ ɛzɩ calɩm taa kʋdɔŋ ŋgʋ payaɣ se polypose adénomateuse familiale (PAF) yɔ.

4. Wezuu caɣʋ: Ye ɛyʋ ɛkɩlɩɣ tɔɔʋ nandʋ, ɛkɩlɩɣ hɩlɩm tɔɔʋ, ɛñɔʋ sɩgaa nɛ ɛkpaŋɩɣ sʋlʋm yɔ, pɩpɩzɩɣ piyele nɛ ɛ-yɔɔ cɛ.

5. Calɩm hosi kʊdɔŋ: Calɩm hosi kʊdɔŋ ŋgʊ kɩɖɛʊ nɛ pɩɖɛɣ yɔ, ɛzɩ calɩm hosi kʊdɔŋ yɔ, kɩpɩzɩɣ nɛ kɩha ɛyʋ calɩm hosi nzɩ sɩɖɛʊ nɛ sɩɖɛɣ yɔ nɛ pɩkpaɖɩ.

6. Kʋdɔŋ kɩtɩŋgʋ: Mba pɛwɛnɩ kʋdɔŋ ŋgʋ yɔ, papɩzɩɣ nɛ pɛwɛɛnɩ ɖɔɖɔ lotu taa kʋdɔŋ ŋgʋ payaɣ se cancer yɔ.

7. (a) Calɩm mbʋ payaɣ se radiation yɔ: Calɩm mbʋ palakɩnɩ tʋmɩyɛ lotu taa kʋdɔmɩŋ lɛɛŋ yɔɔ yɔ, pɩpɩzɩɣ piyele nɛ ɛyʋ hiɣ tɔnʋʋ taa kʋdɔŋ.

8. (a) Ɛyaa mba pɛkɛ Afrɩka nɛ Amerika ñɩma yɔ, ɖoŋ ɖoŋ lɛ, kʋdɔŋ ŋgʋ kɩkpa-wɛ nɛ pɩkɩlɩ ɛyaa lalaa.

Pɩcɛyaa se ɖɩtɩlɩ se ye kʋdɔŋ piye nɖɩ ɖɩkpa nɔɔyʋ yɔ, pɩtɩwɩlɩ se ɛkaɣ kɛʋ kʋdɔndʋ.

Ye ɖɩlakɩ kʋdɔŋ ŋgʋ kɩ-tɛ kɔyɛ ɖoŋ ɖoŋ nɛ ɖɩnaɣ-kʋ lɔŋ yɔ, pɩsɩɣnɩ-ɖʋ nɛ ɖɩtaatɔlɩ kɩ-taa yaa ɖɩtɩlɩ kʋdɔŋ ŋgʋ kɩ-tɛ kajalaɣ ñɩŋgʋ alɩwaatʋ ndʋ kɩ-kʋdɔŋ cɛyaa yɔ.

['Takayɩhatʋ ndʋ tɩtamsɩna \\ yɔ']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.

Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.

Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.

Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.

Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.

Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.

Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.

['Tɔm ndʋ tɩ-yɔɔ ɖitisiɣ yɔ: ɖɔkɔtɔ']

['Ye ŋwobi intɛrnɛɛtɩ lone ɖɩnɛ ɖɩ-yɔɔ yɔ, ŋpɩzɩɣ nɛ ŋkpɛlɩkɩ tɔm sakɩyɛ ɖɩ-yɔɔ.']

['Pɩtɩpɔzɩ se patɩŋnɩ tɔm ndʋ pama takayaɣ kanɛ ka-taa yɔ tɩ-yɔɔ nɛ pañɩnɩ kʋdɔŋ nakʋyʋ yaa pawaa-kʋ.']

['Tɩlɩ camɩyɛ se ordinatɛɛrɩ yɔɔ tɔm ndʋ pɔpɔzʋʋ yɔ, tɩ-yɔɔ cosuu wɛ kaɖɛ, kɔzɩ kɔzɩ alɩwaatʋ ndʋ tɩ-taa pɔpɔzʋʋ tɔm natʋyʋ nɛ tɩ-taa tɔm pee tɩɖɔɔ yɔ.']

['Paa ɛzɩmtaa lɛ, pɔzɩ lɔŋ tasʋʋ fɛɖʋ weyi ɛsɩm ñɔ-yɔɔ tɔm sakɩyɛ yɔ nɛ ɛyɔɔdɩ-ŋ kʋdɔŋ ŋgʋ ŋwɛna yɔ kɩ-tɔm. Taayele nɛ lɔŋ tasʋʋ mbʋ fɛɖʋ ɛnʋ ɛha-ŋ yɔ, pɩɖɛɛ ñɔ-yɔɔ yaa ŋyele-pʋ ñɩnʋʋ mbʋ pʋyɔɔ yɔ ŋkalɩ tɔm natʋyʋ intɛrnɛɛtɩ lone ɖɩnɛ ɖɩ-yɔɔ. Ye ŋmaɣzɩɣ se pɩwɩɣ-ŋ yɔ, yaa ɛyaa 911 yaa ŋwolo ɖɔkɔtɔ ŋgʋ kɩñɔtɩnɩ-ŋ yɔ kɩ-taa kpaagbaa.']

['Takayɩhatʋ ndʋ tɩtamsɩna \\ Paɣtʋ \\ yɔ']

['Digital Millennium Copyright Act 1998 ñɩŋgʋ, 17 U.S.C. § 512 (DMCA) haɣ waɖɛ mba pɛwɛnɩ waɖɛ se pala tʋmɩyɛ intɛrnɛɛtɩ yɔɔ yɔ se pala mbʋ pɩkaɖɩɣnɩ waɖɛ nɖɩ pɛwɛna Etaazuunii ɛjaɖɛ taa yɔ.']

['Ye ŋmaɣzɩɣ se tɔm natʋyʋ yaa wonuu nakʋyʋ yɔɔ pama tɔm intɛrnɛɛtɩ lone ɖɩnɛ ɖɩ-yɔɔ yaa intɛrnɛɛtɩ lone ɖɩnɛ ɖɩ-yɔɔ nɛ pɩkaɖɩɣnɩ ña-paɣtʋ yɔ, ña-maɣmaɣ yaa weyi ɛsɩɣ-ŋ tʋmɩyɛ yɔ, ŋpɩzɩɣ nɛ ŋtiyini-ɖʋ takayaɣ nɛ ŋpɔzɩ se ɖɩlɩzɩ tɔm ndʋ yaa wonuu ŋgʋ yaa ɖitaayele nɛ nɔɔyʋ tɩlɩ-kʋ.']

['Pɩwɛɛ se pama takayaɣ nɛ petiyini ordinatɛɛrɩ yɔɔ.']

['DMCA paɣtʋ pɔzʋʋ se ye ŋnawa se nɔɔyʋ tɩma takayaɣ nakɛyɛ yɔ, ŋma tɔm tʋnɛ: (1) takayaɣ ŋga ŋnawa se nɔɔyʋ tɩma-kɛ yɔ kɔ-yɔɔ tɔm; (2) takayaɣ ŋga kɔ-yɔɔ pamawa se nɔɔyʋ tɩma takayaɣ nakɛyɛ yɔ kɔ-yɔɔ tɔm nɛ tɔm ndʋ tɩsɩɣnɩ-ɖʋ se ɖɩtɩlɩ ɖenɖe ŋnaɣ takayaɣ ŋga yɔ; (3) ña-hɩɖɛ, kaŋgalaafu mayaɣ nɛ intɛrnɛɛtɩ mayaɣ; (4) ŋyɔɔdɩ kpayɩ se ŋwɛnɩ tisuu se takayaɣ ŋga ŋnawa se nɔɔyʋ tɩma-kɛ yɔ, pɩtɩkɛ weyi ɛtɩnɩ takayaɣ ŋga yɔ ɛ-maɣmaɣ ɛlɩzɩnɩ-kɛ, yaa ɛ-tʋmlaɖʋ nɔɔyʋ lɩzɩnɩ-kɛ, yaa se paɣtʋ natʋyʋ ɛɛhaɣ nʋmɔʋ se palabɩnɩ-kɛ tʋmɩyɛ.']

['(5) Ye ŋlabɩ mbʋ yɔ, ŋpɩzɩɣ nɛ ŋcɛtɩnɩ ñɔ-tɔm yɔɔ nɛ ŋyɔɔdɩ se tɔm ndʋ pama takayaɣ ŋga ka-taa yɔ tɩkɛ toovenim nɛ ŋwɛnɩ waɖɛ se ŋlʋ nɛ ŋwa mba payʋsʋʋ se pɛwɛɛkɩ ña-takayaɣ yɔ.']

['Nɛ (6) ye nɔɔyʋ ɛtɩnɩ takayaɣ nakɛyɛ yɔɔ tɔm yɔ, pɩwɛɛ se ɛñɩɣ nesi takayaɣ ŋga kɔ-yɔɔ.']

['Ye patɩyɔɔdɩ tɔm ndʋ tɩ-tɩŋa yɔ, pɩpɩzɩɣ nɛ pɩkɔnɩ tɔm hʋʋ kaɖɛ.']

['Ɛyʋ weyi ŋkatɩɣ yɔ']

['Ye ŋwɛnɩ tɔm natʋyʋ yaa ŋñɩnɩɣ se ŋtasɩ tɔm natʋyʋ yɔ, ɖitendi-ŋ ma-ɖʋ takayaɣ.']

What causes colon cancer?

Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.

The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.

These include:

1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.

2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.

3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.

4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.

5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.

6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.

7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.

8. Race: African Americans have a higher risk of developing colon cancer than other races.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.

Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.

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