Pathophysiologie ya diabete ke tendulaka kulonguka ya mambu ya ke salamaka na nitu ya muntu yina ke nataka na diabete.
Diabete mellitus kele kimvuka ya maladi yina ke salaka nde muntu kuvanda ti sukali mingi na menga.
Mambu ya ke salaka nde muntu kukuma ti maladi ya diabete ke vandaka mingi, mu mbandu mambu ya ke salamaka na nitu, na kisika yina muntu ke zingaka, mpi mutindu ya kuzinga.
Na diabete ya mutindu ya 1, maladi yango ke katukaka na mutindu baselile ya beta yina ke basisaka insuline ke fwaka na pankreas, mpi yo ke salaka nde baselile yina kubasisa ve insuline mingi.
Yo ke salaka nde menga kukuma ve ti sukadi mingi, mpi yo ke nataka maladi ya menga yina ke bingaka hyperglycémie.
Na diabete ya mutindu ya 2, maladi yango ke vandaka mpasi mpi yo ke vandaka ti bupusi na mutindu muntu ke salaka ve insuline mpi ke basisaka yo ve mbote.
Bantu ke kumaka ti maladi ya ke salaka nde baselile ya nitu kusala ve mbote ti insuline, yo yina bo ke kumaka ve ti ngolo ya kusadila glucose sambu na kubaka ngolo.
Yo ke salaka nde pankreas kubasisa insuline mingi sambu yo nunga maladi yina, kansi na nima ya ntangu, pankreas lenda kuka diaka ve kubasisa yo, mpi yo ke salaka nde yo basisa ve insuline mingi.
Diabete ya bankento yina ke bakaka divumu, yina ke basikaka na ntangu ya divumu, ke katukaka na bansoba ya ba hormone yina ke salaka nde muntu kukuma ti maladi ya ke salaka nde yandi kuka ve kusadila insuline.
Placenta kebasisaka ba hormone yina lenda kanga kisalu ya insuline, ebuna yo kenataka na kutombuka ya sukadi na menga.
Diabete ke salaka nde muntu kukuma ti maladi ya nkaka, mu mbandu kubeba ya misisa ya menga, ya nitu, mpi ya nitu ya nkaka, yina lenda sala nde muntu kukuma ti maladi ya ngolo bonso maladi ya ntima, ya ntu, ya bapiku, mpi kuvidisa meso.
Kubakisa mambu ya ke salaka nde muntu kubela diabete kele mfunu mingi sambu na kuzaba mutindu ya mbote ya kubelula maladi yai mpi mutindu ya kubuya yo.
Biochemistry and pathophysiology of diabetes. Proceedings of conference on pathophysiology and treatment of diabetes mellitus. 1990. Mol Cell Biochem. 1992, 109 (2): 97-204.
Surampudi PN, John-Kalarickal J, Fonseca VA: Emerging concepts in the pathophysiology of type 2 diabetes mellitus. Mt Sinai J Med. 2009, 76 (3): 216-26.
Johnson D: Selected pathophysiology of diabetes. Semin Perioper Nurs. 1998, 7 (3): 164-78.
Hirsch IB: The changing faces of diabetes. Prim Care. 2003, 30 (3): 499-510.
Guthrie RA, Guthrie DW: Pathophysiology of diabetes mellitus. Crit Care Nurs Q. , 27 (2): 113-25.
Felig P: Pathophysiology of diabetes mellitus. Med Clin North Am. 1971, 55 (4): 821-34.
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What is pathophysiology of diabetes?
Pathophysiology of diabetes refers to the study of the disordered physiological processes that lead to the development of diabetes mellitus.
Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels that result from defects in insulin secretion, insulin action, or both.
The pathophysiology of diabetes involves the complex interplay of genetic, environmental, and lifestyle factors that contribute to the development of the disease.
In type 1 diabetes, the pathophysiology involves an autoimmune destruction of the insulin-producing beta cells in the pancreas, leading to a deficiency in insulin production.
This results in an inability to regulate blood glucose levels, leading to hyperglycemia (high blood sugar).
In type 2 diabetes, the pathophysiology is more complex and involves both insulin resistance and impaired insulin secretion.
Insulin resistance occurs when the body's cells do not respond properly to insulin, leading to an inability to effectively use glucose for energy.
This causes the pancreas to produce more insulin to try to overcome the resistance, but over time, the pancreas may not be able to keep up with the demand, leading to a decrease in insulin production.
Gestational diabetes, which occurs during pregnancy, is caused by hormonal changes that lead to insulin resistance.
The placenta produces hormones that can block the action of insulin, leading to an increase in blood glucose levels.
The pathophysiology of diabetes also involves the development of complications, such as damage to blood vessels, nerves, and organs, which can lead to serious health problems like heart disease, stroke, kidney disease, and vision loss.
Understanding the pathophysiology of diabetes is crucial for developing effective treatments and prevention strategies for this chronic disease.
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