D'r zien versjèllende behandelingsopties besjikbaar veur prostaatkanker, aafhankelek vaan 't stadium en de agressiviteit vaan de kanker, zoewie de algemeine gezoondheid en de persoeneleke veurkeure vaan de patiënt.
Sommige algemeine behandelinge zien:
1. Aktieve surveillance: Deze benadering behels nauwlettend controlere vaan de kanker mèt regelmaoteg controle en teste, in plaots vaan direk mèt de behandeling te beginne.
't Kan gesjik zien veur manslui mèt prostata-kanker mèt 'n lieg risico.
2. Chirurgie: 'n Prostaatverwijdering is 'n chirurgische procedure um de prostaatklier te verwiere.
't Kan via ope chirurgie of laparoscopisch (mèt klein insnijdinge en gespecialiseerde gereidsjappe) weure gedoon.
3. Bestralingstherapie: Dees behandeling gebruuk hoegenergie bestraling um kankercelle te doed te make.
't Kin extern (vaan 'n machine boete 't lief) of intern (door middel vaan implantate in de buurt vaan de tumor) weure toegedeend.
4. Hormoontherapie: Dees behandeling verlaogt 't niveau vaan manneleke hormone (androgene) in 't lief, wat de greuj vaan prostaatkanker kin vertraoge of stoppe.
't Kan allein of in combinatie mèt aander behandelinge weure gebruuk.
5. Chemotherapie: Dees behandeling gebruuk mediciene um kankercelle te doed te make.
't Kan waere gebruuk veur gevorderde prostaatkanker die zich haet verspreid nao anger deile van 't lief.
6. Immunotherapie: Dees behandeling helpt 't immuunsysteem kanker te bestrieje.
't Kan waere gebruuk veur gevorderde prostaatkanker die neet gereageerd haet op anger behandelinge.
7. Gerichte therapie: Dees therapie richt ziech op specifieke gene of proteïne die kankercelle helpe greuje en euverleve.
't Kan waere gebruuk veur gevorderde prostaatkanker die neet gereageerd haet op anger behandelinge.
8. Cryotherapie: Dees behandeling gebroek extreem kou um kankercelle te vrieze en te doed te bringe.
't Kin weure gebruuk veur prostaatkanker in 't beginstadium of veur kanker die is teruggekeerd nao aander behandelinge.
9. Hoegintensief gefocusseerde ultrasone geluidssjtoet (HIFU): Dees behandeling gebruuk hoegfrequente geluidsgolve um kankercelle te verwerme en te vermaore.
't Kin weure gebruuk veur prostaatkanker in 't beginstadium of veur kanker die is teruggekeerd nao aander behandelinge.
10. Wachte: Deze benadering behels nauwlettend controlere vaan de kanker mèt regelmaoteg controle en teste, meh beginne neet mèt de behandeling tenzij de symptome versjijne of verandere.
't Kan gesjik zien veur awwere manslui mèt langzaam greujende prostaatkanker en aander serieuze gezondheidsstoestande.
't Is belangriek um alle behandelingsopties te bespreke mèt 'n medisch team um de bèste actie te bepaole veur eder geval.
Wang Y, Chen J, Wu Z, Ding W, Gao S, Gao Y, Xu C: Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it. Br J Pharmacol. 2021, 178 (2): 239-261.
Talkar SS, Patravale VB: Gene Therapy for Prostate Cancer: A Review. Endocr Metab Immune Disord Drug Targets. 2021, 21 (3): 385-396.
Šamija I, Fröbe A: CHALLENGES IN MANIPULATING IMMUNE SYSTEM TO TREAT PROSTATE CANCER. Acta Clin Croat. 2019, 58 (Suppl 2): 76-81.
Akaza H, Hinotsu S, Usami M, Ogawa O, Kagawa S, Kitamura T, Tsukamoto T, Naito S, Hirao Y, Murai M, Yamanaka H, Namiki M: The case for androgen deprivation as primary therapy for early stage disease: results from J-CaP and CaPSURE. J Urol. 2006, 176 (6 Pt 2): S47-9.
Abraham-Miranda J, Awasthi S, Yamoah K: Immunologic disparities in prostate cancer between American men of African and European descent. Crit Rev Oncol Hematol. 2021, 164 (): 103426.
de Vrij J, Willemsen RA, Lindholm L, Hoeben RC, Bangma CH, Barber C, Behr JP, Briggs S, Carlisle R, Cheng WS, Dautzenberg IJ, de Ridder C, Dzojic H, Erbacher P, Essand M, Fisher K, Frazier A, Georgopoulos LJ, Jennings I, Kochanek S, Koppers-Lalic D, Kraaij R, Kreppel F, Magnusson M, Maitland N, Neuberg P, Nugent R, Ogris M, Remy JS, Scaife M, Schenk-Braat E, Schooten E, Seymour L, Slade M, Szyjanowicz P, Totterman T, Uil TG, Ulbrich K, van der Weel L, van Weerden W, Wagner E, Zuber G: Adenovirus-derived vectors for prostate cancer gene therapy. Hum Gene Ther. 2010, 21 (7): 795-805.
Lee E, Ha S, Logan SK: Divergent Androgen Receptor and Beta-Catenin Signaling in Prostate Cancer Cells. PLoS One. 2015, 10 (10): e0141589.
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How to treat prostate cancer?
There are several treatment options available for prostate cancer, depending on the stage and aggressiveness of the cancer, as well as the patient's overall health and personal preferences.
Some common treatments include:
1. Active surveillance: This approach involves closely monitoring the cancer with regular checkups and tests, rather than immediately starting treatment.
It may be suitable for men with low-risk prostate cancer.
2. Surgery: A prostatectomy is a surgical procedure to remove the prostate gland.
It can be done through open surgery or laparoscopically (using small incisions and specialized tools).
3. Radiation therapy: This treatment uses high-energy radiation to kill cancer cells.
It can be delivered externally (from a machine outside the body) or internally (through implants placed near the tumor).
4. Hormone therapy: This treatment reduces the levels of male hormones (androgens) in the body, which can slow or stop the growth of prostate cancer.
It can be used alone or in combination with other treatments.
5. Chemotherapy: This treatment uses drugs to kill cancer cells.
It may be used for advanced prostate cancer that has spread to other parts of the body.
6. Immunotherapy: This treatment helps the immune system fight cancer.
It may be used for advanced prostate cancer that has not responded to other treatments.
7. Targeted therapy: This treatment targets specific genes or proteins that help cancer cells grow and survive.
It may be used for advanced prostate cancer that has not responded to other treatments.
8. Cryotherapy: This treatment uses extreme cold to freeze and kill cancer cells.
It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.
9. High-intensity focused ultrasound (HIFU): This treatment uses high-frequency sound waves to heat and destroy cancer cells.
It may be used for early-stage prostate cancer or for cancer that has come back after other treatments.
10. Watchful waiting: This approach involves closely monitoring the cancer with regular checkups and tests, but not starting treatment unless symptoms appear or change.
It may be suitable for older men with slow-growing prostate cancer and other serious health conditions.
It is important to discuss all treatment options with a healthcare team to determine the best course of action for each individual case.
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