Pathophysiologie ya diabete ezali koyekola makambo ya maladi oyo ememaka na bokono ya diabete.
Diabete mellitus ezali maladi ya métabolisme oyo emonanaka na sukali mingi na makila (glucose) oyo eutaka na mbeba ya kobimisa insulin, ya kosala insulin, to nyonso mibale.
Pathophysiologie ya diabète ezali na boyokani makasi ya ba facteurs génétiques, environnementaux, mpe ya mode de vie oyo esalaka ete maladi yango ekola.
Na diabɛti ya lolenge ya 1, pathophysiologie ezali kobebisa baselile beta oyo ebimisaka insuline na pancréas, oyo esalaka ete insulin ebima malamu te.
Yango esalaka ete likoki ya kobatela sukali na makila ezala te, mpe yango ememaka hyperglycémie (sukari mingi na makila).
Na diabete ya type 2, pathophysiologie ezali makasi mpe ezali na résistance ya insuline mpe na libumu ya insuline.
Insulin resistance esalemaka soki baselile ya nzoto ezali kosala malamu te na insulin, yango esalaka ete glucose esalelama malamu te mpo na kopesa nzoto makasi.
Yango esalaka ete pancréas ebimisa insulin mingi mpo na kolonga maladi yango, kasi nsima ya mwa ntango, pancréas ekoki kokoka lisusu te kosala ndenge oyo esengeli, mpe yango esalaka ete insulin ebima mingi te.
Diabɛti ya basi oyo bazali na zemi, oyo ebimaka na ntango ya zemi, eutaka na mbongwana ya ba hormone oyo esalaka ete moto aboya kosalela insulin.
Placenta ebimisaka ba hormone oyo ekoki kopekisa mosala ya insuline, mpe yango esalaka ete sukali emata na makila.
Pathophysiologie ya diabete ezali mpe na makambo mosusu oyo ekoki kosala ete maladi yango ezwa misisa, na ndakisa kobebisa misisa ya makila, misisa ya nzoto, mpe binama mosusu, oyo ekoki komema na maladi ya makasi lokola maladi ya motema, maladi ya bɔɔngɔ, maladi ya bangei, mpe kokufa miso.
Koyeba maladi ya diabète ezali na ntina mingi mpo na koyeba ndenge ya kosalisa yango mpe ndenge ya kopekisa yango.
Biochemistry and pathophysiology of diabetes. Proceedings of conference on pathophysiology and treatment of diabetes mellitus. 1990. Mol Cell Biochem. 1992, 109 (2): 97-204.
Surampudi PN, John-Kalarickal J, Fonseca VA: Emerging concepts in the pathophysiology of type 2 diabetes mellitus. Mt Sinai J Med. 2009, 76 (3): 216-26.
Johnson D: Selected pathophysiology of diabetes. Semin Perioper Nurs. 1998, 7 (3): 164-78.
Hirsch IB: The changing faces of diabetes. Prim Care. 2003, 30 (3): 499-510.
Guthrie RA, Guthrie DW: Pathophysiology of diabetes mellitus. Crit Care Nurs Q. , 27 (2): 113-25.
Felig P: Pathophysiology of diabetes mellitus. Med Clin North Am. 1971, 55 (4): 821-34.
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What is pathophysiology of diabetes?
Pathophysiology of diabetes refers to the study of the disordered physiological processes that lead to the development of diabetes mellitus.
Diabetes mellitus is a group of metabolic diseases characterized by high blood sugar (glucose) levels that result from defects in insulin secretion, insulin action, or both.
The pathophysiology of diabetes involves the complex interplay of genetic, environmental, and lifestyle factors that contribute to the development of the disease.
In type 1 diabetes, the pathophysiology involves an autoimmune destruction of the insulin-producing beta cells in the pancreas, leading to a deficiency in insulin production.
This results in an inability to regulate blood glucose levels, leading to hyperglycemia (high blood sugar).
In type 2 diabetes, the pathophysiology is more complex and involves both insulin resistance and impaired insulin secretion.
Insulin resistance occurs when the body's cells do not respond properly to insulin, leading to an inability to effectively use glucose for energy.
This causes the pancreas to produce more insulin to try to overcome the resistance, but over time, the pancreas may not be able to keep up with the demand, leading to a decrease in insulin production.
Gestational diabetes, which occurs during pregnancy, is caused by hormonal changes that lead to insulin resistance.
The placenta produces hormones that can block the action of insulin, leading to an increase in blood glucose levels.
The pathophysiology of diabetes also involves the development of complications, such as damage to blood vessels, nerves, and organs, which can lead to serious health problems like heart disease, stroke, kidney disease, and vision loss.
Understanding the pathophysiology of diabetes is crucial for developing effective treatments and prevention strategies for this chronic disease.
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