What are the risk factors for Alzheimer?

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Chì sò i fattur de ris'c per l'Alzheimer?

Gh'è tanti fattur de ris'c per la malatia de Alzheimer, cumprend:

1. Età: El ris'c de sviluppà la malatia de Alzheimer aumenta cun l'età, e la magiur part di gent la vegn diagnosticada dopu i 65 agn.

2. Genetica: Avè una storia familiara de malattia de Alzheimer o portà certi geni, cume el gene APOE-e4, pœu aumentà el ris'c de sviluppà la malattia.

3. Lesiun de la testa: Una storia de trauma sever de la testa o de contusiun multiple pœden aumentà el ris'c de la malatia de Alzheimer.

4. La sanità cardiovascolar: I condizion qe i afecta el coeur e i vas sanguigni, come la pression alta, el colesterol alt, el diabete e l'obesità, pœden aumentar el ris'c de la malatia de Alzheimer.

5. I fattur del stil de vita: Fumà, el consum eccessiv de alcol e la mancanza de esercizi fisich pœden aumentà el ris'c de la malatia de Alzheimer.

6. L'inattività cognitiva: La mancanza de stimol mental e i bas livel de istruzion pœden aumentar el ris'c de la malatia de Alzheimer.

7. I disturbi del sonn: I disturbi del sonn, cuma l'apnea del sonn, pœden aumentar el ris'c de la malatia de Alzheimer.

8. Fattur psicologich: La depressión, el stress e l'isolament social pœden aumentà el ris'c de la malatia de Alzheimer.

L'è important notà che avegh vun o plu de'sti fattur de ris'c el vœl minga dì che una persona la svilupparà la malatia de Alzheimer, e un quai persun senza fattur de ris'c cognossuu pœden sviluppar la malatia.

Però, capì sti fattur de ris'c pœu aiutà i individui a fà dei pass per ridur el ris'c e promœv la salüte del cervel.

['Referenz']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

Borenstein AR, Copenhaver CI, Mortimer JA: Early-life risk factors for Alzheimer disease. Alzheimer Dis Assoc Disord. , 20 (1): 63-72.

Pansari K, Gupta A, Thomas P: Alzheimer's disease and vascular factors: facts and theories. Int J Clin Pract. 2002, 56 (3): 197-203.

Kivipelto M, Helkala EL, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Iivonen S, Mannermaa A, Tuomilehto J, Nissinen A, Soininen H: Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med. 2002, 137 (3): 149-55.

Skoog I, Kalaria RN, Breteler MM: Vascular factors and Alzheimer disease. Alzheimer Dis Assoc Disord. , 13 Suppl 3 (): S106-14.

Bidzan L: [Initial symptoms and risk factors in Alzheimer's dementia]. Psychiatr Pol. , 28 (2): 207-19.

Gorelick PB: Risk factors for vascular dementia and Alzheimer disease. Stroke. 2004, 35 (11 Suppl 1): 2620-2.

Kummer BR, Diaz I, Wu X, Aaroe AE, Chen ML, Iadecola C, Kamel H, Navi BB: Associations between cerebrovascular risk factors and parkinson disease. Ann Neurol. 2019, 86 (4): 572-581.

Luchsinger JA, Reitz C, Honig LS, Tang MX, Shea S, Mayeux R: Aggregation of vascular risk factors and risk of incident Alzheimer disease. Neurology. 2005, 65 (4): 545-51.

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What are the risk factors for alzheimer?

There are several risk factors for Alzheimer's disease, including:

1. Age: The risk of developing Alzheimer's disease increases with age, with most people being diagnosed after the age of 65.

2. Genetics: Having a family history of Alzheimer's disease or carrying certain genes, such as the APOE-e4 gene, can increase the risk of developing the disease.

3. Head injury: A history of severe head trauma or multiple concussions may increase the risk of Alzheimer's disease.

4. Cardiovascular health: Conditions that affect the heart and blood vessels, such as high blood pressure, high cholesterol, diabetes, and obesity, may increase the risk of Alzheimer's disease.

5. Lifestyle factors: Smoking, excessive alcohol consumption, and lack of physical exercise may increase the risk of Alzheimer's disease.

6. Cognitive inactivity: A lack of mental stimulation and low levels of education may increase the risk of Alzheimer's disease.

7. Sleep disorders: Sleep disorders, such as sleep apnea, may increase the risk of Alzheimer's disease.

8. Psychological factors: Depression, stress, and social isolation may increase the risk of Alzheimer's disease.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop Alzheimer's disease, and some people with no known risk factors may still develop the disease.

However, understanding these risk factors can help individuals take steps to reduce their risk and promote brain health.

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