What causes Colon cancer?

['Kelg-y seb-kãngã']

Bõe n wat ne kãnsɛɛrã?

Yaa kõabgã bɩ rektumã pʋgẽ kõab-solgdsã sẽn pa bɩt tɩ zemsã n wat ne kãnsɛɛrã.

B pa mi kãnsɛɛrã sẽn wat ne bũmb ning takɩ ye, la yɛl wʋsg n tõe n kɩt tɩ bãagã paam- a.

Wala makre:

1. Kʋʋlem: Kɩɩs-kʋdgã tõe n paama ned yʋʋm sẽn vẽsg yĩnga.

2. Zak pʋgẽ bãaga: Ned sã n da zoe n bẽe kãnsɛɛr bɩ kõab bãaga, a tõe n wa bẽe bã-kãng n paase.

3. Zĩn-dãmb bãase: Zĩn-dãmb bãas kẽer b sẽn dog ne, wala makre bãag ning b sẽn boond tɩ polypose adénomateuse familiale (PAF) wã, la kãnsɛɛr sẽn tar yĩng bãaga.

4. Vɩɩmã manesem: Rɩ-tɩrsã, nemd nins b sẽn ningd masĩn dãmbẽ wã, b sẽn dɩt tɩ loogdẽ wã, rãamã yũub la f sã n yũud sɩgaar tɩ loogdẽ, tõe n kɩtame tɩ kãnsɛɛr paam-f n paase.

5. Sũyã bãase: Sũyã bãas sẽn kaoosde, wala makre kõs-kʋdgã bãag la Crohn bãagã tõe n kɩtame tɩ kãnsɛɛr paam neda.

6. Sũ-sãams sẽn tɩ loe ne bĩisim: Neb nins sẽn bĩis-b bãas sẽn tɩ loe ne bĩisimã tõe n wa bẽe kãnsɛɛr sẽn yaa kãsenga.

7. Vẽenem tɩbsg: Vẽenem tɩbsg b sẽn maand kãnsɛɛr dãmb a taab sẽn be pʋgã pʋgẽ tõe n kɩtame tɩ kãnsɛɛr sẽn be pʋg-kãsengã pʋgẽ paam pãnga.

8. Buudã: Afirikdisiid nebã tõe n wa paama kãnsɛɛr n yɩɩd buud a taabã.

Yaa tɩlae tɩ d bãng tɩ f sã n tar yell a ye bɩ yell a taab sẽn tõe n wa kɩt tɩ f lebg kãnsɛɛr soaba, pa rat n yeel tɩ f na n wa lebga kãnsɛɛr ye.

B sã n maand vaeesg wakat fãa n bãngd bãagã sã n sɩngame, tõe n sõngame tɩ b ra wa paam kãnsɛɛrã, wall b bãng-a a sɩngrẽ, tɩ b sã n wa yã-a bɩ b tõog n sãoog-a.

['Sõss sẽn tik Biiblã zugu']

PubMed/Medline https://www.nlm.nih.gov/databases/download/pubmed_medline.html

RefinedWeb https://arxiv.org/abs/2306.01116

McWhirter JE, Todd LE, Hoffman-Goetz L: Beliefs about causes of colon cancer by English-as-a-Second-Language Chinese immigrant women to Canada. J Cancer Educ. 2011, 26 (4): 734-9.

Gamble JF: Asbestos and colon cancer: a weight-of-the-evidence review. Environ Health Perspect. 1994, 102 (12): 1038-50.

Ashish S, Raj M: Importance of Early Next-Generation Sequencing in Microsatellite Unstable Colon Cancer With a High Tumor Mutation Burden. Cureus. 2022, 14 (3): e22894.

Xu W, Zhang Y, Chen L, Qiu F, Zhang B, Wu L, Peng Z, Tang H: Up-regulation of CIT promotes the growth of colon cancer cells. Oncotarget. 2017, 8 (42): 71954-71964.

Wang J, Wu HF, Shen W, Xu DY, Ruan TY, Tao GQ, Lu PH: SRPK2 promotes the growth and migration of the colon cancer cells. Gene. 2016, 586 (1): 41-7.

Taketo MM, Edelmann W: Mouse models of colon cancer. Gastroenterology. 2009, 136 (3): 780-98.

Slattery ML, Kerber RA: The impact of family history of colon cancer on survival after diagnosis with colon cancer. Int J Epidemiol. 1995, 24 (5): 888-96.

['Bãngr-gomde: logtoeemdã']

['Yaa zãmsg la kibay kũun yĩng bal la b yiisd sit kãngã, la pa logtoeemdã wɛɛngẽ sagls bɩ tʋʋm-sõng maaneg yĩng ye.']

['B pa segd n tũnug ne kɩbay nins b sẽn kõ wã n bao bãag bɩ zu-loɛɛg tɩɩm ye. Sẽn dat-b tɩbsg b toor segd n tɩ yãa logtor sẽn tar sor n tõe n tɩp-ba.']

['D tẽeg tɩ b sẽn maand to-to n leokd sogsgã to-to wã pa zems ye.']

['Y sã n wa karemd bũmb sẽn be sɩtã pʋgẽ, bɩ y ra tol n yĩm tɩ y segd n tɩ gesa logtor ye. Y sã n tagsdẽ tɩ y tara yĩn-wɩsgr yell bɩ y bool 911 wall y kẽng logtor yirã.']

['Bas-m-yam: sɛbã zãab wɛɛngẽ']

['Digital Millennium Copyright Act sẽn yaa yʋʋmd 1998 soabã, 17 U.S.C. § 512 (DMCA) kõta sor tɩ ned sã n tẽed tɩ bũmb sẽn be ẽntɛrnetã pʋgẽ kɩɩsda a sẽn tar sor n tõe n maan bũmb ninsã, a tõe n tɩ kos n paam n lebse.']

['Yãmb sã n tẽed ne pʋ-peelem tɩ bũmb sẽn be tõnd sɩt wɛɛbã pʋgẽ bɩ tõnd tʋʋm-noyã pʋsẽ n sãamd yãmb dʋrwa wã, yãmb (bɩ y tʋʋm-tʋmdã) tõe n toola tõnd koɛɛg n kos tɩ d yiis bũmbã wall d gɩdg tɩ y ra paam n kẽ ye.']

['B segd n tʋma koees ne ẽtɛrnetã (Ges-y ẽtɛrnetã adɛrs sẽn be babg ning sẽn yet tɩ "Tõnd sõsg zĩigã").']

['DMCA wã baoodame tɩ yãmb sẽn na n togs ned tɩ b maan-a-la bũmb sẽn kɩɩsd a sẽn tar sor n tõe n maan bũmb ningã, bɩ y wilg-a bũmb nins sẽn pʋgdã: 1) bũmb ning sẽn kɩt tɩ b maan-a bũmb ningã, 2) bũmb ning sẽn kɩt tɩ b maan-a bũmb ningã, la y wilg-d bũmb ning sẽn kɩt tɩ d tõe n bãng a sẽn be zĩig ninga. 3) y sẽn tõe n paam ned n gom ne-a to-to, n paas y adɛrsã, telefõnnã nimero, la y e-mailã. 4) y sã n yeel tɩ y kɩsa sɩd tɩ bũmb ning sẽn kɩt tɩ y maan bũmb ningã pa ned ning sẽn tar sor n tõe n maan bũmbã, bɩ a tʋm-tʋmdã, bɩ laloa wã sẽn kõ sor tɩ y maan ye.']

['5) Y sã n wa rat n wilg tɩ y pa tar sor n na n kɩɩs ned a to, bɩ y gʋls sebr n wilg tɩ y sẽn togsã yaa sɩda, la tɩ y tara sor n na n wilg tɩ nedã sẽn maan bũmb ning n kɩɩs yãmb dʋrwa rãmbã yaa sɩda.']

['La (6) sɛb nins sẽn tar-b sor n na n yiis sɛbã, bɩ ned sẽn tar sor n na n tʋm sɛbã yiisg yĩngã.']

['Y sã n pa gʋls kibay nins sẽn be yĩngrã, tõe n kɩtame tɩ y yẽgengã kaoos n pa sa ye.']

['Sõsg ne neda']

['Y sã n tar sokr bɩ y sẽn dat n bãnge, bɩ y gʋls-d lɛtr n tool-do.']

What causes colon cancer?

Colon cancer, also known as colorectal cancer, is caused by the uncontrolled growth of abnormal cells in the colon or rectum.

The exact cause of colon cancer is not known, but several factors can increase the risk of developing the disease.

These include:

1. Age: The risk of colon cancer increases with age, with most cases occurring in people over the age of 50.

2. Family history: A personal or family history of colon cancer or polyps increases the risk of developing the disease.

3. Inherited syndromes: Certain inherited genetic syndromes, such as familial adenomatous polyposis (FAP) and hereditary non-polyposis colorectal cancer (HNPCC), can increase the risk of colon cancer.

4. Lifestyle factors: A diet high in red and processed meats, obesity, smoking, and excessive alcohol consumption can increase the risk of colon cancer.

5. Inflammatory bowel disease: Long-term inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, can increase the risk of colon cancer.

6. Type 2 diabetes: People with type 2 diabetes have an increased risk of developing colon cancer.

7. Radiation therapy: Radiation therapy for other cancers in the abdomen can increase the risk of colon cancer.

8. Race: African Americans have a higher risk of developing colon cancer than other races.

It is important to note that having one or more of these risk factors does not necessarily mean that a person will develop colon cancer, and some people who develop colon cancer may not have any known risk factors.

Regular screening and early detection can help prevent colon cancer or detect it at an early stage when it is most treatable.

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